Abstract：
OBJECTIVE:To determine whether early-gestation vaginal bleeding and elevated maternal serum alpha-fetoprotein (MSAFP) are independent risk factors for adverse infant outcomes. METHODS:We conducted a cohort study of 201 women with an elevated MSAFP (at least 2.0 multiples of the median [MOM]) and a second-trimester ultrasound evaluation at Swedish Hospital Medical Center between January 1989 and March 1991, and 211 women with MSAFP levels below 2.0 MOM who had also undergone ultrasound evaluations during the same period. RESULTS:Stratified analyses demonstrated that early-gestation bleeding and elevated MSAFP were independent risk factors for the delivery of both preterm and low birth weight infants. Compared with women with no history of early-gestation bleeding or elevated MSAFP, women with early-gestation bleeding alone had a relative risk (RR) of preterm delivery of 4.3 (95% confidence interval [CI] 1.5-12.1); non-bleeders with elevated MSAFP had an RR of 4.6 (95% CI 1.9-10.9). A combined history of early-gestation bleeding and elevated MSAFP was associated with an almost sixfold increased risk of preterm delivery (RR 5.8; 95% CI 2.2-15.6). Analyses restricted to women with normal-appearing appearing placentas by second-trimester ultrasound evaluations yielded similar results. CONCLUSIONS:These findings support an earlier report documenting the independence of early-gestation bleeding and elevated MSAFP as predictors of adverse infant outcomes.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Williams MA,Hickok DE,Zingheim RW,Mittendorf R,Kimelman J,Mahony BSsubject
Has Abstractpub_date
1992-11-01 00:00:00pages
745-9issue
5eissn
0029-7844issn
1873-233Xjournal_volume
80pub_type
杂志文章abstract：OBJECTIVE:To estimate the association between state Medicaid coverage of medically necessary abortion and severe maternal morbidity and in-hospital maternal mortality in the United States. METHODS:We used data on pregnancy-related hospitalizations from the Nationwide Inpatient Sample from 2000 to 2011 (weighted n=38,0...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001982
更新日期：2017-05-01 00:00:00
abstract：:Before the discovery of insulin in 1921, pregnancies in women with diabetes mellitus were a rarity because most reproductive-age patients died soon after diagnosis of this illness. In the limited number of pregnancies reported in the pre-insulin era, both perinatal and maternal mortality were approximately 50%, with s...
journal_title：Obstetrics and gynecology
pub_type： 历史文章,杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVE:To examine the association between the mode of delivery and the risk of offspring obesity by age 21 years using a large community-based birth cohort study in Australia. METHODS:We followed-up a subsample of 2,625 offspring for whom we had measured physical assessments, including height and weight at 21 years...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000016
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:To describe episiotomy usage at vaginal delivery in the United States from 1979-1997. METHODS:We used the National Hospital Discharge Survey, a federal database of a national sample of inpatient hospitals. Data from 1979 to 1997 were analyzed using International Classification of Diseases, Ninth Revision, Cl...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(02)02449-3
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVE:To examine current levels, current correlates of, and changes in long-acting reversible contraceptive (LARC) use, including intrauterine devices and implants, among females aged 15-44 years using contraception between 2008-2010 and 2011-2013 with specific attention to associations between race, income, and ag...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001094
更新日期：2015-11-01 00:00:00
abstract：:Levels of five antibiotics used in treating chorioamnionitis were measured in maternal and cord blood and placenta. Ampicillin provided the highest ratio of cord to maternal blood (0.71). Gentamicin was also relatively high in this respect and also had the highest placenta to maternal blood ratio (3.97). Based on thes...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：BACKGROUND:The single-incision midurethral sling has been introduced as an alternative to the traditional midurethral sling. Complications have been reported rarely. CASE:A 57-year-old multiparous woman with history of osteogenesis imperfecta type I underwent single-incision midurethral sling placement for stress urin...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3182431951
更新日期：2012-02-01 00:00:00
abstract：:Torulopsis glabrata is a yeast of low virulence and commensal within the female genitourinary tract. The first case of congenital infection with Torulopsis glabrata was reported in 1980. An additional example of perinatal Torulopsis infection which is associated with maternal sickle cell anemia is reported. The most c...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:Relaxin is a peptide hormone produced solely by the corpus luteum of pregnant women. Extracts of human pregnancy corpora lutea have relaxin activity in bioassay systems. This activity can be measured in a heterologous porcine radioimmunoassay (RIA). Immunoreactive relaxin was undetectable in the RIA in 51 nonpregnant ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：OBJECTIVE:Over-the-counter vaginal lubricants have been shown to negatively affect in vitro sperm motility. The objective of this study was to estimate the effect of vaginal lubricant use during procreative intercourse on natural fertility. METHODS:Women aged 30-44 years with no history of infertility who had been try...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31825b87ae
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:Takotsubo cardiomyopathy is a cardiac condition associated with the acute onset of chest pain, abnormalities in cardiac enzymes and electrocardiogram, and a distinct pattern of left ventricular dysfunction on echocardiography. This case evaluates an obstetric patient diagnosed with Takotsubo cardiomyopathy d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181662cfe
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the feasibility of examining the fetal ear with three-dimensional ultrasound. METHODS:In 125 pregnancies between 19 and 38 weeks of gestation, fetal ears were evaluated by three-dimensional ultrasound. The volume images with surface rendering were analyzed to depict the morphology, lying axis, or...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00021-0
更新日期：1998-04-01 00:00:00
abstract：:A prospective ultrasound study was conducted in 289 uncomplicated pregnancies with gestational ages ranging from 16-40 weeks. Biometric measurements obtained included biparietal diameter (BPD), head and abdominal circumferences, measurements of long bones, and maximal transverse colon diameter. The pattern of small in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of an advanced-practice nurse-obstetrician collaborative prenatal practice. METHODS:A group of 194 consecutively enrolled medically low-risk obstetric patients was identified between January 1, 1994 and December 31, 1994 at Neighborhood Pregnancy Care, a collaborative-practice s...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00649-2
更新日期：1998-02-01 00:00:00
abstract：:Variations of urethral pressure were registered with microtransducers in 427 gynecologic patients with lower urinary tract symptoms during urethrocystometry. Urethral instability (variation of urethral pressure greater than 15 cm of water) was found in 16.4% of patients. The comparison of the urinary symptoms and the ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：OBJECTIVE:To estimate the relationship between hormonal parameters of diminished ovarian reserve and the incidence of aneuploid blastocysts. METHODS:This prospective cohort trial was performed in a private in vitro fertilization clinic. Three hundred seventy-two patients underwent in vitro fertilization with blastocys...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/aog.0b013e318278eeda
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To compare composite maternal and neonatal adverse outcomes among women with at least a bachelor's degree by racial and ethnic groups. METHODS:This was a retrospective cohort study using the U.S. vital statistics data sets. We included women with at least a bachelor's degree who delivered a nonanomalous live...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003887
更新日期：2020-07-01 00:00:00
abstract：:Two hundred ten rats were randomized into one of five study groups to compare standard absorbable sutures with a new synthetic absorbable suture. We evaluated Maxon (polyglyconate), Vicryl (polyglactin), chromic catgut (catgut), and PDS (polydioxanone) with respect to tissue inflammatory reaction, knot security, sutur...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:The current literature suggests that atypical (benign atypia or class II) Papanicolaou smears occur at a frequency of 1.6-5.4% and are associated with a substantial rate of underlying cervical dysplasia. However, we noted that our rate of atypia exceeded these figures, particularly in our clinic population. To quantif...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the role of cerebral velocimetry as a predictor of perinatal outcome in high-risk pregnancies. METHODS:Middle cerebral artery pulsatility index was measured in 576 high-risk pregnancies undergoing umbilical velocimetry. The results of both tests were evaluated with respect to the birth of small f...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00482-1
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVE:To assess the risks of congenital varicella syndrome and other birth defects in offspring of women who inadvertently received varicella vaccine during pregnancy or within 3 months of conception. METHODS:Pregnant women inadvertently exposed to varicella vaccine, reported voluntarily, were enrolled in the Preg...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01384-9
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:To estimate the effect of hormone therapy on risk of stress and urge urinary incontinence. METHODS:The Heart Estrogen/progestin Replacement Study was a randomized, placebo-controlled, double-blinded trial to evaluate daily oral conjugated estrogen (0.625 mg) plus medroxyprogesterone acetate (2.5 mg) therapy ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/01.AOG.0000180394.08406.15
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:Patient-prosthesis mismatch is a known and severe complication after aortic valve repair in the general population. There is a paucity of literature regarding this condition in pregnancy. CASE:We present the clinical course of a pregnant woman with severe patient-prosthesis mismatch after aortic valve repla...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000074
更新日期：2014-02-01 00:00:00
abstract：:Tubal pregnancy specimens from a patient with undetectable serum beta-hCG levels and a control case with a low beta-hCG titer by radioimmunoassay were analyzed using peroxidase-antiperoxidase immunocytochemical localization of placental proteins. The results indicated that deficient production of beta-hCG by ectopic t...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：:We evaluated the effect of birth order on the incidence and severity of intraventricular hemorrhage in 29 sets of very low birth weight twins (1500 g or less). Intraventricular hemorrhage occurred in 55% of first-presenting twins and 62% of second-presenting twins. The incidence of minor intraventricular hemorrhage (g...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:This study was designed to compare the effects of two low-dose triphasic oral contraceptives (OCs) on glucose tolerance and insulin secretion. Fifty-seven women were randomized to receive OCs containing ethinyl estradiol and either levonorgestrel or norethindrone. Ten subjects using nonhormonal contraception served as...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:To evaluate a quality improvement protocol for venous thromboembolism prevention in postoperative gynecologic cancer patients. METHODS:On January 1, 2006, we initiated a universal protocol of dual prophylaxis with sequential compression devices and three times daily heparin (or daily low molecular weight hep...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1097/AOG.0b013e31818b1486
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To compare the outcome of triplet pregnancies reduced to twins who reached 24 weeks' gestation with the outcome of twin pregnancies managed in the same perinatal department. METHODS:The study group included 43 triplet pregnancies reduced to twins who reached 24 weeks' gestation and were delivered between Jan...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(95)00469-6
更新日期：1996-04-01 00:00:00
abstract：:This report describes an innovative use of videography in teaching retropubic space anatomy and surgery. After the standard abdominal incision has been made, the second surgical assistant places a gynecologic laparoscope, fitted with an endoscopic camera, into the retropubic space and guides the laparoscope documentin...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:One hundred fifty-eight cases are reported of fetal cardiocentesis during the second trimester for the prenatal diagnosis of hemoglobinopathies. In all cases, fetal blood sampling by funipuncture was technically impossible or unsuccessful. There were nine fetal deaths possibly related to the procedure, for a total fet...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
