Cardiocentesis: an alternative method of fetal blood sampling for the prenatal diagnosis of hemoglobinopathies.

Abstract:

:One hundred fifty-eight cases are reported of fetal cardiocentesis during the second trimester for the prenatal diagnosis of hemoglobinopathies. In all cases, fetal blood sampling by funipuncture was technically impossible or unsuccessful. There were nine fetal deaths possibly related to the procedure, for a total fetal loss rate of 6.5%. If one fetal loss that occurred 46 days after the procedure is excluded, the total procedure-related fetal loss rate is 5.6%. No cases of maternal chorioamnionitis, fetal cardiac trauma, or hemopericardium were encountered among the living infants. We conclude that cardiocentesis should be offered in highly selective cases when funipuncture is not technically feasible. In experienced hands, the procedure has a fetal loss rate of 6.5% with no morbidity among the survivors.

journal_name

Obstet Gynecol

authors

Antsaklis AI,Papantoniou NE,Mesogitis SA,Koutra PT,Vintzileos AM,Aravantinos DI

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

630-3

issue

4

eissn

0029-7844

issn

1873-233X

journal_volume

79

pub_type

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