ACOG Committee Opinion No. 771 Summary: Umbilical Cord Blood Banking.


:Since the first successful umbilical cord blood transplant in 1988, it has been estimated that more than 35,000 transplants have been performed in children and adults for the correction of inborn errors of metabolism, hematopoietic malignancies, and genetic disorders of the blood and immune system. Two types of banks have emerged for the collection and storage of umbilical cord blood: 1) public banks and 2) private banks. The benefits and limitations of public versus private umbilical cord blood banking should be reviewed with the patient because they serve different purposes. This patient discussion also should include the concept of autologous and allogeneic use of umbilical cord blood. Umbilical cord blood collected from a neonate cannot be used to treat a genetic disease or malignancy in that same individual (autologous transplant) because stored cord blood contains the same genetic variant or premalignant cells that led to the condition being treated. There is no current evidence to support the use of an autologous umbilical cord blood sample in regenerative medicine. Patients should be made aware of the quality control and regulatory organizations that provide oversight for the process of umbilical cord collection and storage. Umbilical cord blood collection should not compromise obstetric or neonatal care or alter routine practice of delayed umbilical cord clamping with the rare exception of medical indications for directed donation. Therefore, it is important to inform patients that the medical condition of the woman or neonate may prevent adequate umbilical cord blood collection. This document is updated with a statement that the routine use of private cord blood banking is not supported by available evidence and that public banking is the recommended method of obtaining cord blood. In addition, the importance of contribution from all ethnicities and races to public banks is highlighted.


Obstet Gynecol





Has Abstract


2019-03-01 00:00:00














  • Short-acting sulfonamides near term and neonatal jaundice.

    abstract:OBJECTIVE:To investigate the association between maternal use of sulfamethizole near term and the risk of neonatal jaundice. METHODS:We conducted a nationwide population-based retrospective cohort study using Danish registers. All Danish women giving birth between 1995 and 2007 were included from the Danish Fertility ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Klarskov P,Andersen JT,Jimenez-Solem E,Torp-Pedersen C,Poulsen HE

    更新日期:2013-07-01 00:00:00

  • Cost-effectiveness of preoperative imaging for appendicitis after indeterminate ultrasonography in the second or third trimester of pregnancy.

    abstract:OBJECTIVE:To assess the cost-effectiveness of diagnostic laparoscopy, computed tomography (CT), and magnetic resonance imaging (MRI) after indeterminate ultrasonography in pregnant women with suspected appendicitis. METHODS:A decision-analytic model was developed to simulate appendicitis during pregnancy taking into c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Kastenberg ZJ,Hurley MP,Luan A,Vasu-Devan V,Spain DA,Owens DK,Goldhaber-Fiebert JD

    更新日期:2013-10-01 00:00:00

  • Efficacy of telephone counseling for pregnant smokers: a randomized controlled trial.

    abstract:OBJECTIVE:Reducing tobacco use in pregnancy is a public health priority. Brief smoking counseling during prenatal care is effective but generates modest cessation rates. Telephone counseling is an effective smoking cessation method that could offer pregnant women convenient access to more intensive smoking cessation co...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验


    authors: Rigotti NA,Park ER,Regan S,Chang Y,Perry K,Loudin B,Quinn V

    更新日期:2006-07-01 00:00:00

  • Assisted reproductive technology and placenta-mediated adverse pregnancy outcomes.

    abstract:OBJECTIVE:To estimate whether the use of specific types of assisted reproductive technology (ART) is associated with an increased risk of placenta-mediated pregnancy complications, which include preeclampsia, stillbirth, small for gestational age at birth, and placental abruption. METHODS:A population-based retrospect...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Sun LM,Walker MC,Cao HL,Yang Q,Duan T,Kingdom JCP

    更新日期:2009-10-01 00:00:00

  • Improved survival of Asians with corpus cancer compared with whites: an analysis of underlying factors.

    abstract:OBJECTIVE:To compare the clinicopathologic prognosticators and survival of Asians and whites with corpus cancer. METHODS:Demographic, clinicopathologic, and survival data were obtained from the 1992-2001 Surveillance, Epidemiology, and End Results Program. Statistical analyses were performed by Kaplan-Meier methods an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Zhang MM,Cheung MK,Osann K,Lee MM,Gomez SS,Whittemore AS,Husain A,Teng NN,Chan JK

    更新日期:2006-02-01 00:00:00

  • Maternal blood C-reactive protein, white blood cell count, and temperature in preterm labor: a comparison with amniotic fluid white blood cell count.

    abstract:OBJECTIVE:To compare the diagnostic and prognostic performance of maternal blood C-reactive protein, white blood cell count (WBC), and temperature with that of amniotic fluid (AF) WBC in preterm labor. METHODS:One hundred two women with preterm labor and intact membranes were studied. Maternal blood was collected to m...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Yoon BH,Yang SH,Jun JK,Park KH,Kim CJ,Romero R

    更新日期:1996-02-01 00:00:00

  • Abnormalities of lymphocyte transformations in women with intraepithelial carcinoma of the vulva.

    abstract::Cellular immunity of the delayed type in women with intraepithelial carcinoma (carcinoma is situ) of the vulva was investigated by an in vitro assay of mitogen-induced lymphocyte transformations. Test results from 9 patients were compared to those of 23 age-matched control subjects. Lymphocyte transformation responses...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Seski JC,Reinhalter ER,Silva J Jr

    更新日期:1978-09-01 00:00:00

  • Urinary calcium as an early marker for preeclampsia.

    abstract::Women who develop preeclampsia during pregnancy excrete less calcium than healthy pregnant women. Whether this reduction in calcium excretion precedes or follows hypertension is unknown. We prospectively measured urinary calcium excretion in 103 consecutive nulliparous women at risk for preeclampsia and presenting for...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Sanchez-Ramos L,Jones DC,Cullen MT

    更新日期:1991-05-01 00:00:00

  • Vascular endothelial growth factor serum concentrations in ovarian cancer.

    abstract:OBJECTIVE:To determine whether serum vascular endothelial growth factor is an independent prognostic factor in ovarian cancer patients. METHODS:We measured vascular endothelial growth factor in pretreatment serum samples of 60 women with International Federation of Gynecology and Obstetrics stages I to IV epithelial o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Tempfer C,Obermair A,Hefler L,Haeusler G,Gitsch G,Kainz C

    更新日期:1998-09-01 00:00:00

  • Combination of pessary and periurethral collagen injections for nonsurgical treatment of uterovaginal prolapse and genuine stress urinary incontinence.

    abstract:BACKGROUND:The combination of severe uterovaginal prolapse and stress urinary incontinence in medically compromised patients in whom surgery is contraindicated is a difficult treatment dilemma. CASE:A 75-year-old woman with severe cardiac compromise and a history of pulmonary embolus presented with severe uterovaginal...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Walters MD,Iannetta LT

    更新日期:1997-10-01 00:00:00

  • Predicting fetal acidemia using umbilical venous cord gas parameters.

    abstract:OBJECTIVE:To assess the utility of umbilical cord venous blood gas measures for prediction of umbilical artery pH and base deficit acidemia. METHODS:A retrospective cohort study was conducted of all singletons with valid paired arterial and venous cord gas samples delivered at our institution from January 2006 to Marc...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Cantu J,Szychowski JM,Li X,Biggio J,Edwards RK,Andrews W,Tita ATN

    更新日期:2014-11-01 00:00:00

  • Association of isolated polyhydramnios at or beyond 34 weeks of gestation and pregnancy outcome.

    abstract:OBJECTIVE:To evaluate pregnancy outcome among women with isolated polyhydramnios at admission for labor at or beyond 34 weeks of gestation. METHODS:Retrospective cohort study at a tertiary medical center between 2007 and 2012. Isolated polyhydramnios was defined as amniotic fluid index (AFI) greater than 25 cm at admi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Aviram A,Salzer L,Hiersch L,Ashwal E,Golan G,Pardo J,Wiznitzer A,Yogev Y

    更新日期:2015-04-01 00:00:00

  • Cervical intraepithelial neoplasia III: long-term outcome after cold-knife conization with clear margins.

    abstract:OBJECTIVE:To evaluate the long-term outcome of patients with severe cervical intraepithelial neoplasia or squamous cell carcinoma in situ (CIN III) after cold-knife conization with clear margins. METHODS:A total of 4417 women (mean age 36, range 18-72 years) with histologically confirmed CIN III had cold-knife conizat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Reich O,Pickel H,Lahousen M,Tamussino K,Winter R

    更新日期:2001-03-01 00:00:00

  • ACOG Practice Bulletin No. 111: Inherited thrombophilias in pregnancy.

    abstract::Inherited thrombophilias are associated with an increased risk of venous thromboembolism and also have been linked to adverse outcomes in pregnancy. However, there is limited evidence to guide screening for and management of these conditions in pregnancy. The purpose of this document is to review common thrombophilias...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章



    更新日期:2010-04-01 00:00:00

  • Prevention of neonatal group B streptococcal disease: intrapartum detection and chemoprophylaxis of heavily colonized parturients.

    abstract::Parturients with heavy vaginal colonization of group B streptococci were selected randomly to receive either penicillin or no antibiotic. A simple and fast latex agglutination test, applied in 8977 consecutive parturients, detected 412 women with heavy colonization with group B streptococcus, 199 of whom were eligible...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Tuppurainen N,Hallman M

    更新日期:1989-04-01 00:00:00

  • Relative frequency of primary ovarian neoplasms: a 10-year review.

    abstract::The relative frequency of ovarian neoplasms varies according to information in different texts. In an attempt to clarify the distribution of primary ovarian neoplasms by decades of life, a 10-year retrospective review of 861 women with a postoperative diagnosis of an ovarian neoplasm was undertaken. Benign cystic tera...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Koonings PP,Campbell K,Mishell DR Jr,Grimes DA

    更新日期:1989-12-01 00:00:00

  • Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To estimate the overall reduction in ovarian cancer risk associated with the use of oral contraceptive pills (OCPs) and whether reduction in risk is affected by specifics of OCP use, such as formulation or duration of use. DATA SOURCES:We searched PubMed, Embase, the Cochrane Database of Systematic Reviews, ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审


    authors: Havrilesky LJ,Moorman PG,Lowery WJ,Gierisch JM,Coeytaux RR,Urrutia RP,Dinan M,McBroom AJ,Hasselblad V,Sanders GD,Myers ER

    更新日期:2013-07-01 00:00:00

  • Clinical evaluation of a new herpes simplex virus ELISA: a rapid diagnostic test for herpes simplex virus.

    abstract::A new sensitive and rapid enzyme-linked immunosorbent assay (ELISA) test (Du Pont HERPCHEK) for the detection of herpes simplex virus (HSV) antigen was evaluated. A total of 563 clinical samples collected from patients attending obstetrics and gynecology and sexually transmitted disease clinics in two geographic locat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Baker DA,Gonik B,Milch PO,Berkowitz A,Lipson S,Verma U

    更新日期:1989-03-01 00:00:00

  • Performance of a new DNA probe for the detection of group B streptococcal colonization of the genital tract.

    abstract:OBJECTIVE:To test the performance characteristics of a new DNA probe designed for the rapid identification of heavy colonization of the genital tract with group B streptococci. METHODS:Vaginal and combined vaginal-perianal samples were collected from 193 pregnant women and cultured on colistin-nalidixic acid agar plat...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章


    authors: Rosa C,Clark P,Duff P

    更新日期:1995-10-01 00:00:00

  • Vaginal Cuff Dehiscence and Evisceration: A Review.

    abstract::Vaginal cuff dehiscence is an infrequent complication of hysterectomy, with the potential for evisceration and additional morbidity. This review aims to describe the incidence, risk factors, preventative measures, and management. Identification of specific risk factors is problematic because many studies either lack c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Nezhat C,Kennedy Burns M,Wood M,Nezhat C,Nezhat A,Nezhat F

    更新日期:2018-10-01 00:00:00

  • Porcine subintestinal submucosal graft augmentation for rectocele repair: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate the effect of porcine subintestinal submucosal graft augmentation on improving anatomic and subjective rectocele repair outcomes compared with native tissue repair. METHODS:We conducted a randomized controlled trial at two sites, including women with at least stage 2 symptomatic rectocele. Anatom...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Sung VW,Rardin CR,Raker CA,Lasala CA,Myers DL

    更新日期:2012-01-01 00:00:00

  • Use of a high-frequency aspiration-biopsy transducer for direct ultrasound-guided amniocentesis.

    abstract::The techniques and applications of amniocentesis performed with a new high-frequency aspiration-biopsy transducer are described in detail. The advantages of this technique are greatest in third-trimester patients where active fetal motion and diminished amniotic fluid volumes make unguided punctures difficult or impos...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Bree RL

    更新日期:1979-04-01 00:00:00

  • Differences in cervical cancer mortality among black and white women.

    abstract:OBJECTIVE:To determine whether stage of disease and treatment patterns account for mortality differences between black and white women with cervical cancer. METHODS:Using data obtained from the Surveillance, Epidemiology, and End Results (SEER) Program for 1988-1994, we determined the associations between race and sta...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Howell EA,Chen YT,Concato J

    更新日期:1999-10-01 00:00:00

  • Foley Bulb Insertion by Blind Placement Compared With Direct Visualization: A Randomized Controlled Trial.

    abstract:OBJECTIVE:To test the hypothesis that digital placement of a balloon catheter is not inferior to the speculum method in terms of rate of maternal infection. METHODS:In an open-label noninferiority randomized trial, pregnant women who were undergoing induction of labor with unfavorable cervix (less than 3 cm dilated an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Kuhlmann MJ,Spencer N,Garcia-Jasso C,Singh P,Abdelwahab M,Vaughn M,Marshall K,Prasad N,Soulsby-Monroy R,Saade GR,Saad AF

    更新日期:2021-01-01 00:00:00

  • Surgical cytoreduction for disseminated benign disease after open power uterine morcellation.

    abstract:BACKGROUND:Uterine morcellation is a technique used in gynecologic surgery to facilitate a laparoscopic approach to the removal of an enlarged uterus. The safety of this technique has been a source of recent debate, as uterine morcellation can result in the intraperitoneal dissemination of undiagnosed uterine malignanc...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Ramos A,Fader AN,Long Roche K

    更新日期:2015-01-01 00:00:00

  • What Is New in Validation and Simulation Training?: Best Articles From the Past Year.

    abstract::This month we focus on current research in validation and simulation training. Dr. Buek discusses four recent publications, which are concluded with a "bottom line" that is the take-home message. A complete reference for each can be found on on this page along with direct links to the abstracts. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Buek J

    更新日期:2019-12-01 00:00:00

  • Cervical papillomavirus infection and intraepithelial neoplasia: a study of male sexual partners.

    abstract::The male sexual partners of 34 women with cervical condyloma or cervical intraepithelial neoplasia (CIN) were examined for penile condylomata and/or urinary tract lesions. External lesions were detected in 18 (53%) of the male consorts of women with cervical lesions including 14 of 22 whose consorts had cervical condy...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Levine RU,Crum CP,Herman E,Silvers D,Ferenczy A,Richart RM

    更新日期:1984-07-01 00:00:00

  • Filled Prescriptions for Opioids After Vaginal Delivery.

    abstract:OBJECTIVE:To estimate the prevalence of filled opioid prescriptions after vaginal delivery. METHODS:We conducted a retrospective cohort study of 164,720 Medicaid-enrolled women in Pennsylvania who delivered a liveborn neonate vaginally from 2008 to 2013, excluding women who used opioids during pregnancy or who had an ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Jarlenski M,Bodnar LM,Kim JY,Donohue J,Krans EE,Bogen DL

    更新日期:2017-03-01 00:00:00

  • Metabolic parameters and steroid levels in postmenopausal women receiving lower doses of natural estrogen replacement.

    abstract::This study was carried out to determine whether some of the lowest doses of natural estrogens currently prescribed for postmenopausal women result in significant changes in plasma lipids, urinary calcium, urinary free cortisol, or level of androgens. Twenty-four postmenopausal women were studied and the estrogens inge...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Lobo RA,Brenner P,Mishell DR Jr

    更新日期:1983-07-01 00:00:00

  • The impact of National Health Service Corps physicians in the lowering perinatal mortality rate in Dade County, Florida.

    abstract::In some parts of Dade County, Florida, perinatal mortality rates have revealed serious problems in the delivery of health care to poor pregnant women. From 1982-1985, the reported perinatal mortality rates varied from 32-36 per 1000 live births, more than double the national average. Under the leadership of the Primar...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,收录出版


    authors: Nguyen HN,O'Sullivan MJ,Fournier AM

    更新日期:1991-09-01 00:00:00