Effect of vaginal lubricants on natural fertility.

Abstract:

OBJECTIVE:Over-the-counter vaginal lubricants have been shown to negatively affect in vitro sperm motility. The objective of this study was to estimate the effect of vaginal lubricant use during procreative intercourse on natural fertility. METHODS:Women aged 30-44 years with no history of infertility who had been trying to conceive for less than 3 months completed a baseline questionnaire on vaginal lubricant use. Subsequently, women kept a diary to record menstrual bleeding, intercourse, and vaginal lubricant use and conducted standardized pregnancy testing for up to 6 months. Diary data were used to determine the fertile window and delineate lubricant use during the fertile window. A proportional hazards model was used to estimate fecundability ratios with any lubricant use in the fertile window considered as a time-varying exposure. RESULTS:Of the 296 participants, 75 (25%) stated in their baseline questionnaire that they use vaginal lubricants while attempting to conceive. Based on daily diary data, 57% of women never used a lubricant, 29% occasionally used a lubricant, and 14% used a lubricant frequently. Women who used lubricants during the fertile window had similar fecundability to those women who did not use lubricants (fecundability ratio 1.05, 95% confidence interval 0.59-1.85) after adjusting for age, partner race, and intercourse frequency in the fertile window. CONCLUSION:Lubricants are commonly used by couples during procreative intercourse. Lubricant use during procreative intercourse does not appear to reduce the probability of conceiving.

journal_name

Obstet Gynecol

authors

Steiner AZ,Long DL,Tanner C,Herring AH

doi

10.1097/AOG.0b013e31825b87ae

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

44-51

issue

1

eissn

0029-7844

issn

1873-233X

pii

00006250-201207000-00010

journal_volume

120

pub_type

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