Enhancing effect of the endocrine disruptor para-nonylphenol on the generation of reactive oxygen species in human blood neutrophils.

abstract：:Impairment of any of the major components of the immune system (T-cells, B-cells phagocytes, complement) may result in clinical immunodeficiency. Immune defects can arise from intrinsic or heritable defects of lymphoid elements, failure of normal cellular differentiation, viral infection or other acquired causes. Clin...

journal_title：Environmental health perspectives

authors： Heise ER

更新日期：1982-02-01 00:00:00

abstract：:Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1...

journal_title：Environmental health perspectives

authors： Meeker JD,Ryan L,Barr DB,Herrick RF,Bennett DH,Bravo R,Hauser R

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Climate influences dengue ecology by affecting vector dynamics, agent development, and mosquito/human interactions. Although these relationships are known, the impact climate change will have on transmission is unclear. Climate-driven statistical and process-based models are being used to refine our knowledg...

journal_title：Environmental health perspectives

authors： Morin CW,Comrie AC,Ernst K

更新日期：2013-11-01 00:00:00

abstract：:The normal mucociliary epithelium of the respiratory tract in chronic cigarette smokers often is replaced focally by a metaplastic squamous epithelium. Because asbestos workers who smoke have a substantially greater risk of bronchogenic carcinoma than nonsmokers, we hypothesized that interaction of asbestos with squam...

journal_title：Environmental health perspectives

authors： Woodworth CD,Mossman BT,Craighead JE

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these mechanisms could be important effect modifiers. OBJECTIVE:Our goal was to assess interactions between exposure to air pollution and single nucleotide polymorphisms (S...

journal_title：Environmental health perspectives

authors： Melén E,Nyberg F,Lindgren CM,Berglind N,Zucchelli M,Nordling E,Hallberg J,Svartengren M,Morgenstern R,Kere J,Bellander T,Wickman M,Pershagen G

更新日期：2008-08-01 00:00:00

abstract：:The National Urban Air Toxics Research Center (NUATRC) hosted its first scientific workshop in 1994 that focused on possible relationships between air toxics and asthma. From that meeting came recommendations for future research including a need for more complete individual personal exposure assessments so that determ...

journal_title：Environmental health perspectives

authors： Larsen GL,Beskid C,Shirnamé-Moré L

更新日期：2002-08-01 00:00:00

abstract：:Pyrethroids are important insecticides used in agriculture, forestry, horticulture, and in the home. In humans, they are rapidly metabolized and renally eliminated. In numerous studies, pyrethroid metabolites have been detected in urine after occupational exposure to insecticides. In this study, we used a new, reliabl...

journal_title：Environmental health perspectives

authors： Heudorf U,Angerer J

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Tens of millions of Americans suffer from a range of adverse health outcomes due to noise exposure, including heart disease and hearing loss. Reducing environmental noise pollution is achievable and consistent with national prevention goals, yet there is no national plan to reduce environmental noise polluti...

journal_title：Environmental health perspectives

authors： Hammer MS,Swinburn TK,Neitzel RL

更新日期：2014-02-01 00:00:00

abstract：:Methylcobalamin (methyl-B12) has been implicated in the biomethylation of the heavy metals (mercury, tin, platinum, gold, and thallium) as well as the metalloids (arsenic, selenium, tellurium and sulfur). In addition, methylcobalamin has been shown to react with lead, but the lead-alkyl product is unstable in water. D...

journal_title：Environmental health perspectives

authors： Ridley WP,Dizikes L,Cheh A,Wood JM

更新日期：1977-08-01 00:00:00

abstract：:It has been estimated that 4 of 1,000 live births and 35% of spontaneous abortions are aneuploid and that an important proportion of embryo and newborn aneuploidy is of paternal origin. Exposure to organophosphorous pesticides (OP) has been associated with sperm hyperploidy/polyploidy. Therefore, we aimed to assess th...

journal_title：Environmental health perspectives

authors： Recio R,Robbins WA,Borja-Aburto V,Morán-Martínez J,Froines JR,Hernández RM,Cebrián ME

更新日期：2001-12-01 00:00:00

abstract：:Because of rampant concern that estrogenic chemicals in the environment may be adversely affecting the health of humans and wildlife, reliable methods for detecting and characterizing estrogenic chemicals are needed. It is important that general agreement be reached on which tests to use and that these tests then be a...

journal_title：Environmental health perspectives

authors： Shelby MD,Newbold RR,Tully DB,Chae K,Davis VL

更新日期：1996-12-01 00:00:00

abstract：:Elemental boron was isolated in 1808. It typically occurs in nature as borates hydrated with varying amounts of water. Important compounds are boric acid and borax. Boron compounds are also used in the production of metals, enamels, and glasses. In trace amounts, boron is essential for the growth of many plants, and i...

journal_title：Environmental health perspectives

authors： Moseman RF

更新日期：1994-11-01 00:00:00

abstract：:Free-radical metabolites can be generated metabolically by a one-electron reductase-catalyzed reaction or a "peroxidase" catalyzed oxidation or by photoactivation of a wide variety of aromatic xenobiotics. Radicals may also be generated during lipid peroxidation. Some radicals can react with DNA or bind covalently or ...

journal_title：Environmental health perspectives

authors： O'Brien PJ

更新日期：1985-12-01 00:00:00

abstract：:This paper reports on the prevalence of lead poisoning in children between 1 and 5 years of age living in a marginal area to the north of Mexico City and also includes an evaluation of sources of exposure to this metal in the same area. The results show that 67.5% of the children studied have blood lead (PbB) levels >...

journal_title：Environmental health perspectives

authors： López-Carrillo L,Torres-Sánchez L,Garrido F,Papaqui-Hernández J,Palazuelos-Rendón E,López-Cervantes M

更新日期：1996-11-01 00:00:00

abstract：:In this study we investigated the risk of hearing loss among workers exposed to both toluene and noise. We recruited 58 workers at an adhesive materials manufacturing plant who were exposured to both toluene and noise [78.6-87.1 A-weighted decibels; dB(A)], 58 workers exposed to noise only [83.5-90.1 dB(A)], and 58 ad...

journal_title：Environmental health perspectives

authors： Chang SJ,Chen CJ,Lien CH,Sung FC

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Despite experimental evidence, most epidemiologic studies to date have not supported an association between exposure to persistent organic pollutants (POP) and breast cancer incidence in humans. This may be attributable to difficulties in estimating blood/tissue POP concentration at critical time periods of ...

journal_title：Environmental health perspectives

authors： Verner MA,Charbonneau M,López-Carrillo L,Haddad S

更新日期：2008-07-01 00:00:00

abstract：:The industrial accident that occurred in the town of Seveso, Italy, in 1976 exposed a large population to substantial amounts of relatively pure 2,3,7,8-tetrachlorodibenzo-p-dioxin. Extensive monitoring of soil levels and measurements of a limited number of human blood samples allowed classification of the exposed pop...

journal_title：Environmental health perspectives

authors： Bertazzi PA,Bernucci I,Brambilla G,Consonni D,Pesatori AC

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:THE APHENA (AIR POLLUTION AND HEALTH: A Combined European and North American Approach) study is a collaborative analysis of multicity time-series data on the effect of air pollution on population health, bringing together data from the European APHEA (Air Pollution and Health: A European Approach) and U.S. N...

journal_title：Environmental health perspectives

authors： Samoli E,Peng R,Ramsay T,Pipikou M,Touloumi G,Dominici F,Burnett R,Cohen A,Krewski D,Samet J,Katsouyanni K

更新日期：2008-11-01 00:00:00

abstract：:The types of reactive intermediates generated upon reduction of chromium(VI) by glutathione or hydrogen peroxide and the resulting DNA damage have been determined. In vitro, reaction of chromium(VI) with glutathione led to formation of two chromium(V) complexes and the glutathione thiyl radical. When chromium(VI) was ...

journal_title：Environmental health perspectives

authors： Aiyar J,Berkovits HJ,Floyd RA,Wetterhahn KE

更新日期：1991-05-01 00:00:00

abstract：:Studies conducted by the National Toxicology Program on the chronic toxicity of benzene indicated that B6C3F1 mice were more sensitive to the carcinogenic effects of benzene than were F344 rats. A physiological model was developed to describe the uptake and metabolism of benzene in rats and mice. Our objective was to ...

journal_title：Environmental health perspectives

authors： Medinsky MA,Sabourin PJ,Henderson RF,Lucier G,Birnbaum LS

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Urbanization has been correlated with hypertension (HTN) in developing countries undergoing rapid economic and environmental transitions. OBJECTIVES:We examined the relationships among living environment (urban, suburban, and rural), day/night land surface temperatures (LST), and blood pressure in selected ...

journal_title：Environmental health perspectives

authors： Estes MG Jr,Al-Hamdan MZ,Crosson W,Estes SM,Quattrochi D,Kent S,McClure LA

更新日期：2009-12-01 00:00:00

abstract：:Droplets of toluene and three chlorinated organics, ortho-dichlorobenzene, 1,2-dichloroethane, and trichloroethylene, were pyrolyzed in pure nitrogen. The composition and bacterial mutagenicity of the product tars were measured. The presence of organic chlorine was found to affect both pyrolysis product tar compositio...

journal_title：Environmental health perspectives

authors： Mulholland JA,Sarofim AF,Longwell JP,Lafleur AL,Thilly WG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The widespread use of organophosphorus (OP) pesticides has led to frequent exposure in adults and children. Because such exposure may cause adverse health effects, particularly in children, the sources and patterns of exposure need to be studied further. OBJECTIVES:We assessed young urban/suburban children'...

journal_title：Environmental health perspectives

authors： Lu C,Barr DB,Pearson MA,Waller LA

更新日期：2008-04-01 00:00:00

abstract：:Although most people are thought to receive their highest acute exposures to gasoline while refueling, relatively little is actually known about personal, nonoccupational exposures to gasoline during refueling activities. This study was designed to measure exposures associated with the use of an oxygenated fuel under ...

journal_title：Environmental health perspectives

authors： Backer LC,Egeland GM,Ashley DL,Lawryk NJ,Weisel CP,White MC,Bundy T,Shortt E,Middaugh JP

更新日期：1997-08-01 00:00:00

abstract：:Short-term increases in ambient air pollution have been associated with an increased incidence of acute cardiac events. We assessed the effect of inhalation exposure to concentrated ambient particles (CAPs) on myocardial ischemia in a canine model of coronary artery occlusion. Six mongrel dogs underwent thoracotomy fo...

journal_title：Environmental health perspectives

authors： Wellenius GA,Coull BA,Godleski JJ,Koutrakis P,Okabe K,Savage ST,Lawrence JE,Murthy GG,Verrier RL

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Inorganic arsenic (iAs) causes cancer and possibly other adverse health outcomes. Arsenic-based drugs are permitted in poultry production; however, the contribution of chicken consumption to iAs intake is unknown. OBJECTIVES:We sought to characterize the arsenic species profile in chicken meat and estimate ...

journal_title：Environmental health perspectives

authors： Nachman KE,Baron PA,Raber G,Francesconi KA,Navas-Acien A,Love DC

更新日期：2013-07-01 00:00:00

abstract：:An intercomparison exercise was conducted for the quantification of arsenic species in spiked human urine. The primary objective of the exercise was to determine the variance among laboratories in the analysis of arsenic species such as inorganic As (As+3 and As+5), monomethylarsonic acid (MMA), and dimethylarsinic ac...

journal_title：Environmental health perspectives

authors： Crecelius E,Yager J

更新日期：1997-06-01 00:00:00

abstract：:Building-related illness ranges from mild rhinitis to potentially life-threatening hypersensitivity pneumonitis and legionellosis. Sick-building syndrome, consisting of headache, mucous membrane irritation, and fatigue, may be present in 30% of all office workers. Hypersensitivity pneumonitis, asthma, and legionellosi...

journal_title：Environmental health perspectives

authors： Welch LS

更新日期：1991-11-01 00:00:00

abstract：:To analyze the implications for human health, the toxicologist requires four sets of data: the results of toxicity and other studies in animals; quantitative data on actual or potential human exposure; whatever information is available on effects of exposure in man; and the statistical extrapolations from the dose-res...

journal_title：Environmental health perspectives

authors： Golberg L

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure in utero and during early postnatal development increases the incidence of asthma and airway hyperresponsiveness (AHR) later in life, suggesting that a possible critical period of developmental sensitivity exists in the prenatal and early postnatal periods. OBJECTIVE:We investigated...

journal_title：Environmental health perspectives

authors： Wu ZX,Hunter DD,Kish VL,Benders KM,Batchelor TP,Dey RD

更新日期：2009-09-01 00:00:00