Severity of health effects associated with building-related illness.

abstract：:The additives and contaminants which occur in textile fibers vary widely, depending on the type of fiber and the pretreatment which it has received. Synthetic fibers such as nylon and polyester contain trace amounts of contaminants such as catalysts and catalyst deactivators which remain after the synthesis of the bas...

journal_title：Environmental health perspectives

authors： Barker RH

更新日期：1975-06-01 00:00:00

abstract：:The X-ray crystallographic structural determinations of synthetic estrogens and antiestrogens provide reliable information on the global minimum energy conformation of these molecules or a local minimum energy conformation that is within 1 or 2 kcal/mole of the global minimum. In favorable cases, state-of-the-art mole...

journal_title：Environmental health perspectives

authors： Duax WL,Griffin JF,Weeks CM,Korach KS

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Radon is the second-leading cause of lung cancer worldwide. Most indoor exposure occurs by diffusion of soil gas. Radon is also found in well water, natural gas, and ambient air. Pennsylvania has high indoor radon concentrations; buildings are often tested during real estate transactions, with results report...

journal_title：Environmental health perspectives

authors： Casey JA,Ogburn EL,Rasmussen SG,Irving JK,Pollak J,Locke PA,Schwartz BS

更新日期：2015-11-01 00:00:00

abstract：:The Thomsen-Friedenreich antigen (Gal-GalNAc) represents a tumor-associated molecule, which is assumed to be one of the few chemically well-defined antigens with a proven association with malignancy. In order to analyze the role of the carbohydrate structure Gal-GalNAc for gastrointestinal tumors, we immunized Balb/c ...

journal_title：Environmental health perspectives

authors： Dippold W,Steinborn A,Meyer zum Büschenfelde KH

更新日期：1990-08-01 00:00:00

abstract：:The remarkable frequency of uterine leiomyoma in the human population calls into question the potential for the participation of environmental factors in tumor etiology. Having been implicated in the dramatic rise in hormone-related cancers in recent years, endocrine disruptors are salient suspects in this pathogenesi...

journal_title：Environmental health perspectives

authors： Hunter DS,Hodges LC,Eagon PK,Vonier PM,Fuchs-Young R,Bergerson JS,Walker CL

更新日期：2000-10-01 00:00:00

abstract：:Cofactors involved in respiratory tract carcinogenesis were studied in Syrian golden hamsters or in rats using benzo(a)pyrene as the carcinogenic agent. These factors included severe tissue damage induced by electro-coagulation, glass fibers administered by intratracheal instillation, acetaldehyde as irritant vapor, f...

journal_title：Environmental health perspectives

authors： Reuzel PG,Feron VJ,Spit BJ,Beems RB,Kroes R

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVES:The U.S. Environmental Protection Agency is working toward gaining a better understanding of the human health impacts of exposure to complex air pollutant mixtures and the key features that drive the toxicity of these mixtures, which can then be used for future scientific and risk assessments. DATA SOURCES:...

journal_title：Environmental health perspectives

authors： Johns DO,Stanek LW,Walker K,Benromdhane S,Hubbell B,Ross M,Devlin RB,Costa DL,Greenbaum DS

更新日期：2012-09-01 00:00:00

abstract：:Male rats were treated with various model compounds or the appropriate vehicle controls. Most substances were either well-known hepatotoxicants or showed hepatotoxicity during preclinical testing. The aim of the present study was to determine if biological samples from rats treated with various compounds can be classi...

journal_title：Environmental health perspectives

authors： Steiner G,Suter L,Boess F,Gasser R,de Vera MC,Albertini S,Ruepp S

更新日期：2004-08-01 00:00:00

abstract：:We conducted a 1-year epidemiologic study in Boston, Massachusetts, beginning May 1997, to examine the associations between environmental factors and office workers' health. We recruited 98 subjects (81 females and 17 males) in 21 offices in four office buildings. We conducted environmental sampling every 6 weeks and ...

journal_title：Environmental health perspectives

authors： Chao HJ,Schwartz J,Milton DK,Burge HA

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Environmental exposures to phthalates, particularly high-molecular-weight (HMW) phthalates, are suspected to contribute to allergy. OBJECTIVE:We assessed whether phthalate metabolites are associated with allergic symptoms and sensitization in a large nationally representative sample. METHODS:We used data o...

journal_title：Environmental health perspectives

authors： Hoppin JA,Jaramillo R,London SJ,Bertelsen RJ,Salo PM,Sandler DP,Zeldin DC

更新日期：2013-10-01 00:00:00

abstract：:Lead encephalopathy was induced in developing Long-Evans rats by adding lead carbonate (4% w/w) to the diet of nursing mother immediately after delivery. The morphological and biochemical features of cerebral ontogenesis were studied in 30-day-old rats. By the 30th postnatal day, the overall effect of lead intoxicatio...

journal_title：Environmental health perspectives

authors： Krigman MR,Hogan EL

更新日期：1974-05-01 00:00:00

abstract：BACKGROUND:The damaging effects of exposure to environmental toxicants differentially affect genetically distinct individuals, but the mechanisms contributing to these differences are poorly understood. Genetic variation affects the establishment of the gene regulatory landscape and thus gene expression, and we hypothe...

journal_title：Environmental health perspectives

authors： Chappell GA,Israel JW,Simon JM,Pott S,Safi A,Eklund K,Sexton KG,Bodnar W,Lieb JD,Crawford GE,Rusyn I,Furey TS

更新日期：2017-10-16 00:00:00

abstract：:The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was i...

journal_title：Environmental health perspectives

authors： Mazzullo M,Bartoli S,Bonora B,Colacci A,Grilli S,Lattanzi G,Niero A,Turina MP,Parodi S

更新日期：1989-07-01 00:00:00

abstract：:This cross-sectional study examined the association between environmental lead measurements surrounding a Los Angeles County battery recycling facility and the blood lead levels of the children living nearby. Environmental lead measurements and blood lead levels of young children living in a community adjacent to a st...

journal_title：Environmental health perspectives

authors： Wohl AR,Dominguez A,Flessel P

更新日期：1996-03-01 00:00:00

abstract：:Relative potencies for 30 compounds scheduled for carcinogenic testing in the 2-year rodent bioassays were estimated based on comparisons with a wide variety of bioassay data for benzo[a]pyrene, nicotine, cisplatin, aflatoxin B1, and cyclophosphamide. Potential for oncogenic transformation of each of the compounds was...

journal_title：Environmental health perspectives

authors： Jones TD,Easterly CE

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Air pollution data in Bangkok, Thailand, indicate that levels of particulate matter with aerodynamic diameter < or = 10 microm (PM(10)) are significantly higher than in most cities in North America and Western Europe, where the health effects of PM(10) are well documented. However, the pollution mix, seasona...

journal_title：Environmental health perspectives

authors： Vichit-Vadakan N,Vajanapoom N,Ostro B

更新日期：2008-09-01 00:00:00

abstract：:While the rat pancreas is susceptible to experimental cancer induction, the spontaneous incidence of pancreatic cancer in this species is reported to be very low. However, we observed unusually high incidences of focal acinar hyperplasia and acinar adenoma in vehicle control male F344/N rats of some NCI/NTP 2-year tox...

journal_title：Environmental health perspectives

authors： Boorman GA,Eustis SL

更新日期：1984-06-01 00:00:00

abstract：:Many naturally occurring and man-made chemicals present in the environment possess estrogenic activity. Examples include plant and fungal products, pesticides, plasticizers, and other agricultural and industrial chemicals. These environmental estrogens as well as endogenous ovarian estrogens are thought to initiate th...

journal_title：Environmental health perspectives

authors： Stancel GM,Boettger-Tong HL,Chiappetta C,Hyder SM,Kirkland JL,Murthy L,Loose-Mitchell DS

更新日期：1995-10-01 00:00:00

abstract：:This study assessed whether exposure of male rats to two estrogenic, environmental chemicals, 4-octylphenol (OP) and butyl benzyl phthalate (BBP) during gestation or during the first 21 days of postnatal life, affected testicular size or spermatogenesis in adulthood (90-95 days of age). Chemicals were administered via...

journal_title：Environmental health perspectives

authors： Sharpe RM,Fisher JS,Millar MM,Jobling S,Sumpter JP

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. OBJECTIVES:This study was designed to evaluate whether pren...

journal_title：Environmental health perspectives

authors： Xia W,Du X,Zheng T,Zhang B,Li Y,Bassig BA,Zhou A,Wang Y,Xiong C,Li Z,Yao Y,Hu J,Zhou Y,Liu J,Xue W,Ma Y,Pan X,Peng Y,Xu S

更新日期：2016-01-01 00:00:00

abstract：:The lead exposure of children and their mothers has been studied in two towns with mean soil lead contents of 900 and 400 ppm. No significant difference in blood or fecal lead contents was demonstrated between the two populations, but a small difference in hair lead content was shown. The blood lead content of childre...

journal_title：Environmental health perspectives

authors： Barltrop D,Strehlow CD,Thorton I,Webb JS

更新日期：1974-05-01 00:00:00

abstract：:Methyl parathion (MP), an organophosphate pesticide licensed only for agricultural uses, was sprayed illegally for pest control in Mississippi and Ohio residences. To evaluate the association between MP exposure and neurobehavioral development, we assessed children 6 years or younger at the time of the spraying and lo...

journal_title：Environmental health perspectives

authors： Ruckart PZ,Kakolewski K,Bove FJ,Kaye WE

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region. OBJECTIVES:We aimed to elucidate the association between environmental and infectious exposures and cirrhosis in...

journal_title：Environmental health perspectives

authors： Kuniholm MH,Lesi OA,Mendy M,Akano AO,Sam O,Hall AJ,Whittle H,Bah E,Goedert JJ,Hainaut P,Kirk GD

更新日期：2008-11-01 00:00:00

abstract：:The in vivo effects of xenoestrogens are of interest in relation to their potential health risks and/or beneficial effects on humans and animals. However, the apparent in vivo potency of the examined response can be confounded by a short half-life, and the metabolism of estrogens is very dependent on the nature of con...

journal_title：Environmental health perspectives

authors： Milligan SR,Balasubramanian AV,Kalita JC

更新日期：1998-01-01 00:00:00

abstract：:Recent increases have been reported in industrial countries for several sites of cancer. The causes of these increases remain unknown. Efforts should proceed to identify those occupational groups with increases in the same sites, as these may indicate relevant exposures. Two analyses were undertaken: trends in cancer ...

journal_title：Environmental health perspectives

authors： Davis DL,Blair A,Hoel DG

更新日期：1993-04-01 00:00:00

abstract：:Differences in genetic susceptibility to hazardous chemicals affect individuals of both human and nonhuman populations. In both cases, differences in response to chemicals or general ill health result as a function of these differences in genetic susceptibility. However, ecological systems are a compilation of hundred...

journal_title：Environmental health perspectives

authors： Burger J

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Cadmium (Cd) is a human toxicant and carcinogen. Genetic variation might affect long-term accumulation. Cd is absorbed via iron transporters. OBJECTIVES:We evaluated the impact of iron homeostasis genes [divalent metal transporter 1 (SLC11A2), transferrin (TF), transferrin receptors (TFR2 and TFRC), and fer...

journal_title：Environmental health perspectives

authors： Rentschler G,Kippler M,Axmon A,Raqib R,Ekström EC,Skerfving S,Vahter M,Broberg K

更新日期：2013-04-01 00:00:00

abstract：:Ambient monitoring of acid aerosols in four U.S. cities and in a rural region of southern Ontario clearly show distinct periods of strong acidity. Measurements made in Kingston, TN, and Steubenville, OH, resulted in 24-hr H+ ion concentrations exceeding 100 nmole/m3 more than 10 times during summer months. Periods of ...

journal_title：Environmental health perspectives

authors： Spengler JD,Keeler GJ,Koutrakis P,Ryan PB,Raizenne M,Franklin CA

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Genetics may partially explain observed heterogeneity in associations between traffic-related air pollution and incident asthma. OBJECTIVE:Our aim was to investigate the impact of gene variants associated with oxidative stress and inflammation on associations between air pollution and incident childhood ast...

journal_title：Environmental health perspectives

authors： MacIntyre EA,Brauer M,Melén E,Bauer CP,Bauer M,Berdel D,Bergström A,Brunekreef B,Chan-Yeung M,Klümper C,Fuertes E,Gehring U,Gref A,Heinrich J,Herbarth O,Kerkhof M,Koppelman GH,Kozyrskyj AL,Pershagen G,Postma DS,Th

更新日期：2014-04-01 00:00:00

abstract：:The discovery of the potent mutagenicity of AF-2, which was once used in Japan as a food preservative, has exerted a great influence not only on screening procedures for carcinogenic compounds but also on legislative approaches to mutagenic substances. It promoted the synthesis of exceedingly sensitive and reliable te...

journal_title：Environmental health perspectives

authors： Tazima Y

更新日期：1979-04-01 00:00:00