Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study.

abstract：BACKGROUND AND PURPOSE:Angiographic vasospasm frequently complicates subarachnoid hemorrhage and has been implicated in the development of delayed cerebral ischemia. Whether large-vessel narrowing adequately accounts for the critical reductions in regional cerebral blood flow underlying ischemia is unclear. We sought t...

journal_title：Stroke

authors： Dhar R,Scalfani MT,Blackburn S,Zazulia AR,Videen T,Diringer M

更新日期：2012-07-01 00:00:00

abstract：:Background and Purpose- Prehospital routing algorithms for patients with suspected stroke because of large vessel occlusions should account for likelihood of benefit from endovascular therapy (EVT), risk of alteplase delays, and transport times. We built a mathematical model to give a real-time, location-based optimal...

journal_title：Stroke

authors： Ali A,Zachrison KS,Eschenfeldt PC,Schwamm LH,Hur C

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care...

journal_title：Stroke

authors： Hsiao J,Sayles E,Antzoulatos E,Stanton RJ,Sucharew H,Broderick JP,Demel SL,Flaherty ML,Grossman AW,Kircher C,Kreitzer N,Peariso K,Prestigiacomo CJ,Shirani P,Walsh KB,Lampton H,Adeoye O,Khatri P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Nimodipine, a calcium antagonist, has been reported to have beneficial effects in acute ischemic infarction. Some calcium channel antagonists have antiplatelet effects. We investigated the effect of oral nimodipine on platelet function in healthy volunteers. METHODS:Twelve healthy volunteers (6 ...

journal_title：Stroke

authors： Feinberg WM,Bruck DC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular reserve (CVR) by both transcranial Doppler ultrasonography (TCD) and quantitative cerebral blood flow (CBF) can identify subgroups of patients at increased risk for stroke. A direct comparison of CVR measurements obtained with both technologies in patients with cerebrovascular occ...

journal_title：Stroke

authors： Pindzola RR,Balzer JR,Nemoto EM,Goldstein S,Yonas H

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aim was to explore whether the mismatch in lesion visibility between b1000 and b0 images is an alternative to mismatch between diffusion-weighted imaging and fluid-attenuated inversion recovery imaging as a surrogate marker of stroke age. METHODS:We analyzed patients from the European multic...

journal_title：Stroke

authors： Geraldo AF,Berner LP,Haesebaert J,Chabrol A,Cho TH,Derex L,Hermier M,Louis-Tisserand G,Chamard L,Klaerke Mikkelsen I,Ribe L,Østergaard L,Hjort N,Pedraza S,Thomalla G,Baron JC,Nighoghossian N,Berthèzene Y

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported poor outcomes in patients too good to treat with intravenous thrombolysis because of mild or rapidly improving symptoms. We sought to determine baseline clinical and imaging predictors of poor outcome in these patients. METHODS:Among 3950 consecutive stroke admissio...

journal_title：Stroke

authors： Ali SF,Siddiqui K,Ay H,Silverman S,Singhal A,Viswanathan A,Rost N,Lev M,Schwamm LH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of patients with spontaneous cerebral artery dissection show ultrastructural alterations in dermal collagen and elastic fibers. METHODS:We studied the gene encoding tropoelastin (ELN) by reverse transcription-polymerase chain reaction and subsequent sequence analysis in 10 patients ...

journal_title：Stroke

authors： Grond-Ginsbach C,Thomas-Feles C,Werner I,Weber R,Wigger F,Hausser I,Brandt T

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased amount of therapy seems to be beneficial for motor recovery after stroke. The primary aim of the present study was to evaluate the effect of a 4-week community-based intensive motor training program combined with early supported discharge after initial treatment in a comprehensive strok...

journal_title：Stroke

authors： Askim T,Mørkved S,Engen A,Roos K,Aas T,Indredavik B

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after mechanical thrombectomy for ischemic stroke may be influenced by blood pressure (BP). This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy. METHODS:SIESTA (Sedation vs Intub...

journal_title：Stroke

authors： Schönenberger S,Uhlmann L,Ungerer M,Pfaff J,Nagel S,Klose C,Bendszus M,Wick W,Ringleb PA,Kieser M,Möhlenbruch MA,Bösel J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some strokes of unknown etiology may be the result of a paradoxical embolism traversing through a nonfused foramen ovale (patent foramen ovale [PFO]). The utility of percutaneously placed devices for treatment of patients with cryptogenic stroke or transient ischemic attack (TIA) and PFO is unkno...

journal_title：Stroke

authors： Furlan AJ,Reisman M,Massaro J,Mauri L,Adams H,Albers GW,Felberg R,Herrmann H,Kar S,Landzberg M,Raizner A,Wechsler L,CLOSURE I Investigators.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00

abstract：:The levels of lipid peroxides, determined as thiobarbituric acid reactive substances (TBARS), and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), were examined in the blood from stroke-prone spontaneously hypertensive rats (SHRSP), with and without cerebral lesions, and normotensive W...

journal_title：Stroke

authors： Tomita I,Sano M,Serizawa S,Ohta K,Katou M

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:cerebral small vessel disease (SVD) is the most common cause of vascular dementia. Interest in the use of surrogate markers is increasing. The aims of this study were to determine if brain volume was different between patients with SVD and control subjects, whether it correlated with cognition in...

journal_title：Stroke

authors： Nitkunan A,Lanfranconi S,Charlton RA,Barrick TR,Markus HS

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prompt recognition of stroke symptoms is critical to timely treatment and women have increased delay to treatment. Women may be more likely to present with atypical symptoms, but this hypothesis has not been extensively evaluated. METHODS:We examined gender differences in the prevalence of prese...

journal_title：Stroke

authors： Stuart-Shor EM,Wellenius GA,DelloIacono DM,Mittleman MA

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The trends in stroke incidence reported so far have not been entirely consistent, although declining trends in mortality from stroke have been reported from a number of studies around the world. This study aims to evaluate the 10-year trends (from 1983 through 1992) in incidence, attack rate, and...

journal_title：Stroke

authors： Tuomilehto J,Rastenyte D,Sivenius J,Sarti C,Immonen-Räihä P,Kaarsalo E,Kuulasmaa K,Narva EV,Salomaa V,Salmi K,Torppa J

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from recent multicenter carotid endarterectomy trials have questioned the validity and reliability of Doppler ultrasound in the assessment of carotid stenosis. METHODS:We prospectively analyzed 45 patients undergoing carotid angiography to compare the North American Symptomatic Carotid Enda...

journal_title：Stroke

authors： Alexandrov AV,Bladin CF,Maggisano R,Norris JW

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was to evaluate the accuracy of each parameter o...

journal_title：Stroke

authors： Espinosa de Rueda M,Parrilla G,Manzano-Fernández S,García-Villalba B,Zamarro J,Hernández-Fernández F,Sánchez-Vizcaino C,Carreón E,Morales A,Moreno A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke and systemic embolic events are known to occur as complications of hypertrophic cardiomyopathy (HCM), and these complications are more common in patients with accompanying atrial fibrillation (AF). The diagnosis of AF is sometimes difficult, however, and it is possible that subclinical asy...

journal_title：Stroke

authors： Haruki S,Minami Y,Hagiwara N

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of this study was to validate the comparability of CTP and MRP me...

journal_title：Stroke

authors： Lin L,Bivard A,Levi CR,Parsons MW

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...

journal_title：Stroke

authors： Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

更新日期：1999-12-01 00:00:00

abstract：:Two hundred fifteen consecutive patients with cerebrovascular events were evaluated prospectively for the incidence and characteristics of headache. Of 163 patients able to communicate, headache occurred in 29% with bland infarcts, 57% with parenchymal hemorrhage, 36% with transient ischemic attacks and 17% with lacun...

journal_title：Stroke

authors： Portenoy RK,Abissi CJ,Lipton RB,Berger AR,Mebler MF,Baglivo J,Solomon S

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is little reported of the safety and efficacy of high-dose intravenous recombinant tissue plasminogen activator (alteplase) in combination with heparin anticoagulation in patients presenting with acute ischemic stroke. METHODS:Thirty-two patients with severe hemispheric stroke syndrome cau...

journal_title：Stroke

authors： von Kummer R,Hacke W

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Less than half of acute ischemic stroke patients treated with mechanical thrombectomy obtain permanent clinical benefits. Consequently, there is an urgent need to identify mechanisms implicated in the limited efficacy of early reperfusion. We evaluated the predictors and prognostic significance o...

journal_title：Stroke

authors： Renú A,Laredo C,Lopez-Rueda A,Llull L,Tudela R,San-Roman L,Urra X,Blasco J,Macho J,Oleaga L,Chamorro A,Amaro S

更新日期：2017-03-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies indicate that mild hypothermia provides substantial neuroprotection. However, current systems transfer insufficient heat to rapidly vary core temperature. We thus evaluated the safety and efficacy of endovascular cooling and rewarming for the induction and reversal of hypothermia...

journal_title：Stroke

authors： Dae MW,Gao DW,Ursell PC,Stillson CA,Sessler DI

更新日期：2003-03-01 00:00:00

abstract：:The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrova...

journal_title：Stroke

authors： Boysen G,Sørensen PS,Juhler M,Andersen AR,Boas J,Olsen JS,Joensen P

更新日期：1988-10-01 00:00:00

abstract：:The relationship between central conduction time (CCT) and levels of regional blood flow were studied in 9 primates. Flows were recorded in both hemispheres using the method of hydrogen (2 min) clearance. The somatosensory evoked potentials were recorded over the contralateral cortex and the dorsal columns, following ...

journal_title：Stroke

authors： Hargadine JR,Branston NM,Symon L

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...

journal_title：Stroke

authors： Sirén AL,Liu Y,Feuerstein G,Hallenbeck JM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether diff...

journal_title：Stroke

authors： Peruzzotti-Jametti L,Cambiaghi M,Bacigaluppi M,Gallizioli M,Gaude E,Mari S,Sandrone S,Cursi M,Teneud L,Comi G,Musco G,Martino G,Leocani L

更新日期：2013-11-01 00:00:00