Fluctuation of lipid peroxides and related enzyme activities at time of stroke in stroke-prone spontaneously hypertensive rats.

abstract：BACKGROUND AND PURPOSE:Multiple brain infarcts are often seen on diffusion-weighted images in cardioembolic stroke patients. Recently, mobile aortic plaques (MAPs) have been proposed as embolic sources. However, the clinical characteristics of patients with MAPs are unclear. METHODS:We prospectively studied patients w...

journal_title：Stroke

authors： Ueno Y,Kimura K,Iguchi Y,Shibazaki K,Inoue T,Hattori N,Urabe T

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted MRI (DWI) and perfusion-weighted MRI (PWI) are new techniques that can be used for the evaluation of acute ischemic stroke. However, their potential role in the management of patients treated with recombinant tissue plasminogen activator (rtPA) has yet to be determined. CASE DESCRIPTION:T...

journal_title：Stroke

authors： Lansberg MG,Tong DC,Norbash AM,Yenari MA,Moseley ME

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The collagen alpha2(I) gene (COL1A2) on chromosome 7q22.1, a positional and functional candidate for intracranial aneurysm (IA), was extensively screened for susceptibility in Japanese IA patients. METHODS:Twenty-one single nucleotide polymorphisms (SNPs) of COL1A2 were genotyped in genomic DNA ...

journal_title：Stroke

authors： Yoneyama T,Kasuya H,Onda H,Akagawa H,Hashiguchi K,Nakajima T,Hori T,Inoue I

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spontaneous echo contrast (SEC) is thought to represent a risk factor for cardioembolic stroke. In vitro studies suggest that SEC results from interaction between red cells and fibrinogen. To better understand the relation between SEC and stroke and to investigate the in vivo genesis of SEC, we e...

journal_title：Stroke

authors： Briley DP,Giraud GD,Beamer NB,Spear EM,Grauer SE,Edwards JM,Clark WM,Sexton GJ,Coull BM

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...

journal_title：Stroke

authors： Thorén M,Azevedo E,Dawson J,Egido JA,Falcou A,Ford GA,Holmin S,Mikulik R,Ollikainen J,Wahlgren N,Ahmed N

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perihematomal edema (PHE) is associated with poor outcomes after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a therapeutic target and window for intervention. We studied the effect of PHE volume expansion in the first 72 hours (iPHE) and its relationship w...

journal_title：Stroke

authors： Murthy SB,Moradiya Y,Dawson J,Lees KR,Hanley DF,Ziai WC,VISTA-ICH Collaborators.

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fever after aneurysmal subarachnoid hemorrhage is associated with poor outcome. Because hydrocephalus and extravasated blood may influence thermoregulation, we determined whether these factors increase the risk for fever after subarachnoid hemorrhage. METHODS:Fever within 14 days (subdivided int...

journal_title：Stroke

authors： Dorhout Mees SM,Luitse MJ,van den Bergh WM,Rinkel GJ

更新日期：2008-07-01 00:00:00

abstract：:A patient with diffuse and focal cerebral dysfunction was found to have absent peripheral pulses. Cerbral angiography revealed evidence of an arteritis with bilateral high grade carotid stenosis. When there was no laboratory confirmation of the arteritis, an iatrogenic etiology (ergotism) was suspected. This was later...

journal_title：Stroke

authors： Senter HJ,Lieverman AN,Pinto R

更新日期：1976-01-01 00:00:00

abstract：:Continuous-wave Doppler sonography is a reliable method for detecting severe subclavian stenosis and occlusion as well as subclavian steal. Intermediate stages leading to subclavian steal can also be detected. These are characterized by a cardiac-phase-dependent alternating flow direction in the vertebral artery. Some...

journal_title：Stroke

authors： von Reutern GM,Pourcelot L

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with intracerebral hemorrhage and intraventricular hemorrhage have a reported mortality of 50% to 80%. We evaluated a clot lytic treatment strategy for these patients in terms of mortality, ventricular infection, and bleeding safety events, and for its effect on the rate of intraventricu...

journal_title：Stroke

authors： Naff N,Williams MA,Keyl PM,Tuhrim S,Bullock MR,Mayer SA,Coplin W,Narayan R,Haines S,Cruz-Flores S,Zuccarello M,Brock D,Awad I,Ziai WC,Marmarou A,Rhoney D,McBee N,Lane K,Hanley DF Jr

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...

journal_title：Stroke

authors： Achrol AS,Pawlikowska L,McCulloch CE,Poon KY,Ha C,Zaroff JG,Johnston SC,Lee C,Lawton MT,Sidney S,Marchuk DA,Kwok PY,Young WL,UCSF BAVM Study Project.

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purposes of this study were to assess the relationships between anatomic and technical factors and the 30-day risk of stroke or death after carotid angioplasty and stenting in the Endarterectomy versus Stenting in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial and to perform...

journal_title：Stroke

authors： Naggara O,Touzé E,Beyssen B,Trinquart L,Chatellier G,Meder JF,Mas JL,EVA-3S Investigators.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

journal_title：Stroke

authors： Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether and how the arterial pathology underlying lacunar ischemic stroke differs from the atherothrombotic processes causing most other ischemic strokes is still debated. Different risks of recurrent stroke and MI after lacunar versus nonlacunar ischemic stroke may support a distinct lacunar art...

journal_title：Stroke

authors： Jackson CA,Hutchison A,Dennis MS,Wardlaw JM,Lewis SC,Sudlow CL

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to assess whether the PHASES score allows to (1) match decisions taken by multidisciplinary team whether to observe or intervene, (2) classify patients being diagnosed with a ruptured versus unruptured intracranial aneurysm (UIA), and (3) discriminate patients at low risk...

journal_title：Stroke

authors： Bijlenga P,Gondar R,Schilling S,Morel S,Hirsch S,Cuony J,Corniola MV,Perren F,Rüfenacht D,Schaller K

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to cl...

journal_title：Stroke

authors： Saini M,Ikram K,Hilal S,Qiu A,Venketasubramanian N,Chen C

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that intravenous administration of basic fibroblast growth factor (bFGF) during 4 hours of permanent focal ischemia would affect acute brain injury. METHODS:Halothane-anesthetized cats underwent left middle cerebral artery (MCA) occlusion for 4 hours. Control cats receiv...

journal_title：Stroke

authors： Bethel A,Kirsch JR,Koehler RC,Finklestein SP,Traystman RJ

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS:In vitro studies involved serum deprivation of rat embryonic cortical neurons and ...

journal_title：Stroke

authors： Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...

journal_title：Stroke

authors： Roy D,Soucy JP,Hartman NG,Janicki C,Weill A,Guilbert F,Papineau K,Raymond J

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate the mechanisms for oxidative injury caused by subarachnoid hemolysate, a pro-oxidant. METHODS:Injection of 50 microL of subarachnoid hemolysate or saline was performed in CD1 mice (n=75), mutant mice deficient in Mn-superoxide dismutase (Sod2+/-; n=23), and their wild-ty...

journal_title：Stroke

authors： Matz PG,Fujimura M,Lewen A,Morita-Fujimura Y,Chan PH

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute basilar artery occlusion, intra-arterial thrombolysis or endovascular mechanical recanalization may result in higher recanalization rates than intravenous thrombolysis. However, many patients are admitted to community hospitals, where endovascular therapy is usually not readily available...

journal_title：Stroke

authors： Pfefferkorn T,Holtmannspötter M,Schmidt C,Bender A,Pfister HW,Straube A,Mayer TE,Brückmann H,Dichgans M,Fesl G

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intraventricular thrombolysis (IVT) is a promising treatment in facilitating intraventricular clot resolution after intraventricular hemorrhage. We examined in-hospital outcomes and resource utilization after thrombolysis in patients with intraventricular hemorrhage requiring ventriculostomy in a...

journal_title：Stroke

authors： Moradiya Y,Murthy SB,Newman-Toker DE,Hanley DF,Ziai WC

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis. METHODS:We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Web of Science. Twenty-two studies comprisi...

journal_title：Stroke

authors： Gouya G,Arrich J,Wolzt M,Huber K,Verheugt FW,Gurbel PA,Pirker-Kees A,Siller-Matula JM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of these experiments was to examine mechanisms by which hypercapnia produces vasodilatation in brain. We examined the hypothesis that dilatation of cerebral arterioles during hypercapnia is dependent on activation of ATP-sensitive potassium channels and formation of nitric oxide. MET...

journal_title：Stroke

authors： Faraci FM,Breese KR,Heistad DD

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI trials evaluated the safety and efficacy of thrombectomy in the treatment of intracranial arterial occlusions within 8 hours of symptom onset. We sought to determine the predictors of clinical and angiographic outcomes in...

journal_title：Stroke

authors： Nogueira RG,Liebeskind DS,Sung G,Duckwiler G,Smith WS,MERCI.,Multi MERCI Writing Committee.

更新日期：2009-12-01 00:00:00

abstract：:Background and Purpose- Despite evidence to support the prescription of antihypertensive medications before hospital discharge to promote medication adherence and prevent recurrent events, many patients with stroke miss out on these medications at discharge. We aimed to examine patient, clinical, and system-level diff...

journal_title：Stroke

authors： Dalli LL,Kim J,Thrift AG,Andrew NE,Lannin NA,Anderson CS,Grimley R,Katzenellenbogen JM,Boyd J,Lindley RI,Pollack M,Jude M,Durairaj R,Shah D,Cadilhac DA,Kilkenny MF

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from epidemiological and case-control studies suggest that increased total homocysteine (tHcy) levels are associated with increased risk for thromboembolic disease. The mechanisms by which hyperhomocysteinemia contributes to thrombogenesis are incompletely understood. The main objectives of ...

journal_title：Stroke

authors： Kristensen B,Malm J,Nilsson TK,Hultdin J,Carlberg B,Dahlén G,Olsson T

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...

journal_title：Stroke

authors： Larsson SC,Orsini N

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An association between high lipoprotein(a) [Lp(a)] levels and positive Chlamydia pneumoniae IgG titers in coronary artery disease has been described. The possibility of predicting ischemic stroke by measurements of plasma Lp(a) and C pneumoniae antibodies was investigated. METHODS:This incident ...

journal_title：Stroke

authors： Glader CA,Stegmayr B,Boman J,Stenlund H,Weinehall L,Hallmans G,Dahlén GH

更新日期：1999-10-01 00:00:00