Abstract:
:The effects of ICV administration of CGRP antiserum on active avoidance behavior were studied in rats. CGRP antiserum dilutions of 1:5, 1:10, 1:20, and 1:40 facilitated the extinction of active avoidance responses in a platform-jumping situation in the 3- and 6-h tests. In the 24-h test, only the CGRP antiserum dilution of 1:5 was effective. The present findings suggest that the endogenous CGRP of the brain may be a physiological modulator in extinction processes of active avoidance behavior.
journal_name
Peptidesjournal_title
Peptidesauthors
Kovcs A,Telegdy Gdoi
10.1016/0196-9781(94)90047-7subject
Has Abstractpub_date
1994-01-01 00:00:00pages
893-5issue
5eissn
0196-9781issn
1873-5169pii
0196-9781(94)90047-7journal_volume
15pub_type
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