Dornase alpha and exhaled NO in cystic fibrosis.

abstract：OBJECTIVES:High incidence of genetic alterations at the microsatellite (MS) DNA level has been reported in asthmatic adults. WORKING HYPOTHESIS:The aim of this study was to investigate whether microsatellite instability (MSI) and loss of heterozygosity (LOH) were detectable phenomena in children with asthma. METHODOL...

journal_title：Pediatric pulmonology

authors： Thomou C,Paraskakis E,Neofytou E,Kalmanti M,Siafakas NM,Tzortzaki EG

更新日期：2009-10-01 00:00:00

abstract：:Pseudomonas aeruginosa is often cultured from the airways of children with tracheostomies. P. aeruginosa produces exotoxin A (ETA) and type III cytotoxins. This study tested the hypothesis that children with tracheostomies are colonized by P. aeruginosa that express these virulence factors and will have antibodies dir...

journal_title：Pediatric pulmonology

authors： Rao AR,Splaingard MS,Gershan WM,Havens PL,Thill A,Barbieri JT

更新日期：2005-05-01 00:00:00

abstract：:The pediatric pneumogram is a frequently used tool in the diagnosis and management of apnea during infancy. We analyzed 287 pneumographic recordings from 123 full-term infants (63 males) obtained during the first 12 months of life to establish normative values for apnea, periodic breathing, and bradycardia. The result...

journal_title：Pediatric pulmonology

authors： Kelly DH,Stellwagen LM,Kaitz E,Shannon DC

更新日期：1985-07-01 00:00:00

abstract：:Follow-up studies have demonstrated that bronchiolitis caused by respiratory syncytial virus (RSV) is strongly associated with wheezing in the ensuing years. During the acute infection the immune response may induce long-lasting detrimental effects, thereby contributing to post-bronchiolitis wheezing (PBW). Therefore,...

journal_title：Pediatric pulmonology

authors： van Woensel JB,Kimpen JL,Sprikkelman AB,Ouwehand A,van Aalderen WM

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To carry out a cost-effectiveness analysis of omitting chest radiography in the diagnosis of infant bronchiolitis. HYPOTHESIS:Omitting chest radiographs in the diagnosis of typical bronchiolitis was expected to reduce costs without adversely affecting the detection rate of alternate diseases. STUDY DESIGN:A...

journal_title：Pediatric pulmonology

authors： Yong JH,Schuh S,Rashidi R,Vanderby S,Lau R,Laporte A,Nauenberg E,Ungar WJ

更新日期：2009-02-01 00:00:00

abstract：:Previous research has demonstrated a significant reciprocal relationship between psychosocial factors and asthma morbidity in children. The National Cooperative Inner-City Asthma Study investigated both asthma-specific and non-specific psychosocial variables, including asthma knowledge beliefs and management behavior,...

journal_title：Pediatric pulmonology

authors： Wade S,Weil C,Holden G,Mitchell H,Evans R 3rd,Kruszon-Moran D,Bauman L,Crain E,Eggleston P,Kattan M,Kercsmar C,Leickly F,Malveaux F,Wedner HJ

更新日期：1997-10-01 00:00:00

abstract：:Pulmonary function and exercise tolerance were evaluated in late childhood in two groups of prematurely born children: one group with bronchopulmonary dysplasia (BPD) [n = 15; gestational age at birth (GA): 29.6 +/- 2.8 weeks; birth weight (BW): 1,367 +/- 548 g; age at test: 7.9 +/- 0.6 years], and a second group with...

journal_title：Pediatric pulmonology

authors： Parat S,Moriette G,Delaperche MF,Escourrou P,Denjean A,Gaultier C

更新日期：1995-11-01 00:00:00

abstract：:Malacoplakia is an unusual inflammatory condition with distinctive histologic features. Involvement of the lung is quite uncommon and is rarely described in paediatrics. We report on a case of pulmonary malacoplakia in a teenage girl. ...

journal_title：Pediatric pulmonology

authors： Kumar P,Rassl DM,Hamilton JR,Spencer DA

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

journal_title：Pediatric pulmonology

authors： Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

更新日期：2015-06-01 00:00:00

abstract：:To determine whether doses of ipratropium bromide (IB) greater than those usually administered by aerosol (75-250 micrograms) give a greater degree of protection from exercise-induced asthma (EIA) in children, 12 patients with chronic asthma, ages 7-13 yr, were challenged with methacholine and exercise after inhalatio...

journal_title：Pediatric pulmonology

authors： Boner AL,Vallone G,De Stefano G

更新日期：1989-01-01 00:00:00

abstract：INTRODUCTION:Induced sputum sampling holds promise as a method for obtaining samples representative of the lower airways in young children. Collection of induced sputum samples in young children differs from older children and adults' as pharyngeal suctioning is often required. Our aim was to determine the sensitivity ...

journal_title：Pediatric pulmonology

authors： D'Sylva P,Caudri D,Shaw N,Turkovic L,Douglas T,Bew J,Keil AD,Stick S,Schultz A

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Asthma is the most common chronic disease of childhood. Although asthma admissions to the pediatric intensive care unit (PICU) are increasing, there are no evidence-based guidelines on preferred escalation of therapies for patients with status asthmaticus who fail to respond to inhaled bronchodilators and sys...

journal_title：Pediatric pulmonology

authors： Stulce C,Gouda S,Said SJ,Kane JM

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:To date, no consensus has been reached on the optimal management of congenital lung abnormalities, and factors predicting postnatal outcome have not been identified. We developed an objective quantitative computed tomography (CT) scoring method, and assessed its value for clinical decision-making. METHODS...

journal_title：Pediatric pulmonology

authors： Hermelijn SM,Dragt OV,Bosch JJ,Hijkoop A,Riera L,Ciet P,Wijnen RMH,Schnater JM,Tiddens HAWM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Accelerated lung function decline in cystic fibrosis (CF) is associated with mucoid Pseudomonas aeruginosa infection. Recent data suggest that mucoid P. aeruginosa may amenable to elimination from the airway. We aim to determine whether the initiation of an aggressive antibiotic eradication regimen upon init...

journal_title：Pediatric pulmonology

authors： Troxler RB,Hoover WC,Britton LJ,Gerwin AM,Rowe SM

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:The prognosis of postinfectious bronchiolitis obliterans (PIBO) has many implications, ranging between reduced quality of life and life-threatening complications. We evaluated the prognostic factors for PIBO using the baseline clinical characteristics of patients and built a prediction model for determinin...

journal_title：Pediatric pulmonology

authors： Jung JH,Kim GE,Min IK,Jang H,Kim SY,Kim MJ,Kim YH,Shin HJ,Yoon H,Sohn MH,Lee MJ,Kim KW

更新日期：2020-12-11 00:00:00

abstract：:Prenatal cigarette smoke (CS) exposure, in combination with hypoxia and/or hyperthermia can lead to gasping and attenuated recovery from hypoxia in 7 days old rat pups. We studied 95 unanesthetized spontaneously breathing 14 days old rat pups to investigate if the destabilizing effects of increased ambient temperature...

journal_title：Pediatric pulmonology

authors： Pendlebury JD,Yusuf K,Bano S,Lumb KJ,Schneider JM,Hasan SU

更新日期：2012-05-01 00:00:00

abstract：:The incidence of empyema complicating community-acquired pneumonia is increasing and causes significant childhood morbidity. Pneumococcal infection remains the most common isolated cause in developed countries, with Staphylococcus aureus the predominant pathogen in the developing world. Newer molecular techniques util...

journal_title：Pediatric pulmonology

authors： Jaffé A,Balfour-Lynn IM

更新日期：2005-08-01 00:00:00

abstract：:Changes in the relative contribution of ribcage and abdomen during augmented breaths were assessed in two groups of infants (less than 2 weeks and 4-12 weeks old). In both groups ribcage and abdominal movements increased during augmented breaths in quiet sleep. In the older infants the relative increase was greater fo...

journal_title：Pediatric pulmonology

authors： Mathew OP,Pronske ML,Clark ML

更新日期：1988-01-01 00:00:00

abstract：AIMS:To explore whether gender differences in the Scandinavian Cystic Fibrosis (CF) patients exist in the areas of key clinical parameters, complications, and medication. METHODS:Cross-sectional data on 890 (416 female) pancreatic insufficient CF patients were evaluated regarding chronic infection, body mass index, lu...

journal_title：Pediatric pulmonology

authors： Olesen HV,Pressler T,Hjelte L,Mared L,Lindblad A,Knudsen PK,Laerum BN,Johannesson M,Scandinavian Cystic Fibrosis Study Consortium.

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:The 2017-2018 National Survey of Children's Health estimates that 30 million (42%) US children have experienced at least one adverse childhood experience (ACE), including abuse, neglect, and household dysfunction. ACEs negatively impact long-term health, and there has been no study of ACEs in cystic fibros...

journal_title：Pediatric pulmonology

authors： Williams WA 2nd,Jain M,Laguna TA,McColley SA

更新日期：2020-12-26 00:00:00

abstract：BACKGROUND:Consolidation on chest radiography is widely used as the reference standard for defining pneumonia and variability in interpretation is well known but not well explored or explained. METHODS:Three pediatric sub-specialists (infectious diseases, radiology and respiratory medicine) viewed 3,033 chest radiogra...

journal_title：Pediatric pulmonology

authors： Williams GJ,Macaskill P,Kerr M,Fitzgerald DA,Isaacs D,Codarini M,McCaskill M,Prelog K,Craig JC

更新日期：2013-12-01 00:00:00

abstract：:The term "atypical" pneumonia has been used to differentiate infections caused by Chlamydia pneumoniae, Mycoplasma pneumoniae, Legionella, and other related organisms from pneumonia caused by classic bacteria, the prototype being Streptococcus pneumoniae. However, recent studies demonstrated that the clinical presenta...

journal_title：Pediatric pulmonology

authors： Hammerschlag MR

更新日期：2003-11-01 00:00:00

abstract：:A new method that permits the measurement of adult-type maximal expiratory flow-volume curves and fractional lung volumes in sedated infants was recently described. The purpose of this study was to define the normal range for these new measures of pulmonary function in infants and young children. Measurements of force...

journal_title：Pediatric pulmonology

authors： Castile R,Filbrun D,Flucke R,Franklin W,McCoy K

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To describe the clinical course and treatment of an infant with acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation. DESIGN:Case report. SETTING:A tertiary care University-affiliated hospital. PATIENT, INTERVENTION, AND RESULTS:An 8-month-old girl de...

journal_title：Pediatric pulmonology

authors： Atwa K,Abuhasna S,Shihab Z,Hashaykeh N,Hasan R

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Respiratory illnesses compose the most common diagnoses of patients admitted to pediatric intensive care units. In pediatrics, high-flow nasal cannula (HFNC) therapy is an intermediate level of respiratory support with variability in practice. We conducted a pre-post intervention study of patients placed on H...

journal_title：Pediatric pulmonology

authors： Wiser RK,Smith AC,Khallouq BB,Chen JG

更新日期：2020-12-09 00:00:00

abstract：:The efficacy and tolerability of high-dose salmeterol (100 mcg, BID) and albuterol (2.5 mg, BID) were compared with those of albuterol (2.5 mg, BID) in outpatients with cystic fibrosis in a randomized, double-blind, double-dummy, placebo-controlled, crossover study with both short- (4 weeks of each) and long-term (24 ...

journal_title：Pediatric pulmonology

authors： Hordvik NL,Sammut PH,Judy CG,Colombo JL

更新日期：2002-10-01 00:00:00

abstract：:The purpose of this report is to describe the College of American Pathologists sweat testing (SW) proficiency testing program for cystic fibrosis, to evaluate its impact on test performance, and to describe the current practice of sweat testing in North America. The study analyzed participant summary reports of the SW...

journal_title：Pediatric pulmonology

authors： LeGrys VA

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Methicillin-resistant Staphylococcus aureus (MRSA) infections in cystic fibrosis (CF) patients have greatly increased in prevalence in the past two decades and may lead to a more rapid rate of lung function decline. The objective of this study was to determine the impact of a MRSA eradication protocol on long...

journal_title：Pediatric pulmonology

authors： Belarski E,Pettit R

更新日期：2020-03-01 00:00:00

abstract：:Exposure to chronic constant or intermittent hypoxia (CCH or CIH) may have different effects on growth and development in early life. In this work, we exposed postnatal day 2 (P2) CD1 mice to CCH or CIH (11% O2) for 4 weeks and examined the effect of hypoxia on body and organ growth until P30. Regression analysis show...

journal_title：Pediatric pulmonology

authors： Farahani R,Kanaan A,Gavrialov O,Brunnert S,Douglas RM,Morcillo P,Haddad GG

更新日期：2008-01-01 00:00:00