Abstract：
:We measured soleus H-reflex in the Sprague-Dawley rat as a function of time of day. H-reflex amplitude displayed a marked diurnal variation, even though background EMG and M-response amplitude were stable through the day. The H-reflex was largest in the late morning and smallest around midnight. Thus, its rhythm was opposite in phase to the circadian rhythm found in the primate H-reflex. This rhythm is a potentially confounding factor in studies of motor function. Furthermore, its existence implies that the CNS activity underlying a specific motor performance varies with time of day.
journal_name
Brain Resjournal_title
Brain researchauthors
Chen XY,Wolpaw JRsubject
Has Abstractpub_date
1994-06-13 00:00:00pages
167-70issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(94)91918-6journal_volume
648pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.07.051
更新日期：2015-10-22 00:00:00
abstract：:The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91622-7
更新日期：1986-03-05 00:00:00
abstract：:A group of neurons in the caudal nucleus of the solitary tract (NTS) processes preproglucagon to glucagon-like peptide 1 (GLP-1), GLP-2 and oxyntomodulin. Whereas the anorectic capacity of all three neuropeptides has been demonstrated, only relatively little is known of preproglucagon mRNA regulation in the brain stem...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.10.026
更新日期：2008-01-02 00:00:00
abstract：:(1) The possibility that water intake elicited by the administration of angiotensin-II to the preoptic region (POA), subfornical organ and anterior third ventricle is mediated by separate neural systems was investigated in 58 male Wistar rats using electrolytic lesion techniques. (2) Lesions of the midlateral hypothal...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90189-x
更新日期：1976-05-28 00:00:00
abstract：:The patterns of expression of the Bcl-2, Bax, and Bcl-xL proteins were examined immunocytochemically in rat hippocampus and neocortex after severe hypobaric hypoxia (180 Torr for 3 h) and severe hypoxia preconditioned by intermittent mild hypoxia (360 Torr for 2 h daily, for 3 consecutive days, 24 h prior to severe hy...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.03.053
更新日期：2006-05-17 00:00:00
abstract：:Cerebral blood flow (CBF) and blood flow (BF) in extracerebral head structures were measured during the sleep-wake cycle in rats using radioactive microspheres. While no statistically significant changes occurred in the transition from Waking to quiet sleep (also referred to as synchronized or non-REM Sleep), CBF incr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91813-9
更新日期：1994-03-28 00:00:00
abstract：:30-Day-old male Wistar rats were tested for acquisition and retention of operant conditioned behavior after bilateral subicular lesions made either electrolytically or chemically (ibotenic acid). The acquisition of operant learning was carried out in lesioned rats by assessing the number of sessions required to learn ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01135-3
更新日期：1997-01-16 00:00:00
abstract：:Following acute intracerebroventricular injections of 1 ng of apamin and chronic apamin infusion (0.4 ng/microl, 0.5 microl/h, 14 days), the rat brains exhibited bilateral damage only in the cerebellum. The argyrophilic cells were Purkinje cells in copula pyramis, flocculus, paraflocculus, and paramedian lobules. Thes...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01165-7
更新日期：1997-12-19 00:00:00
abstract：:The responses of spinocervical neurons to sinusoidal hair displacements were studied during and in the absence of radiant heating of parts of the hindpaw to noxious levels (45-65 degrees C). Noxious heat usually increased background discharge and lowered the signal-to-noise ratio at low frequencies of hair displacemen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90949-5
更新日期：1981-10-05 00:00:00
abstract：:Central nervous system (CNS) disorders are important targets for gene therapy; however, delivery of therapeutic proteins and/or genes to the brain remains a major challenge due to the difficulty of efficiently delivering viral vectors across the blood-brain barrier (BBB). In the present work, we tested the ability of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.03.014
更新日期：2011-05-10 00:00:00
abstract：:The biosynthetic activity of extra-hypothalamic vasopressin (VP) neurons in the bed nucleus of the stria terminalis (BNST) is regulated by gonadal steroids. These neurons have also been implicated in a number of behaviors that are impaired in aging. We previously reported that VP mRNA labelling in the BNST is decrease...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(10)80030-7
更新日期：1992-06-26 00:00:00
abstract：:Immunocytochemical and morphometric analyses were combined to demonstrate the presence of neuron subpopulations in the rat vestibular ganglion. Monoclonal antibodies reacting with neurofilament proteins (NF), calbindin-D 28K (CaBP) and calretinin (CaR) were used. Three subpopulations were identified: (1) CaBP- and CaR...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90334-6
更新日期：1992-06-05 00:00:00
abstract：:Clinically, treatment options where fetal distress is anticipated or identified are limited. Allopregnanolone is an endogenous steroid, that positively modulates the GABA(A) receptor, and that has anti-apoptotic and anti-excitotoxic actions, reducing brain damage in adult animal models of brain injury. We sought to de...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.11.035
更新日期：2012-01-18 00:00:00
abstract：:In this study intracellular recording techniques were used to study the synaptic events related to phase-locking of cochlear nucleus cells to low frequency stimuli. A variable degree of phase-locking was noted even with units of the same low characteristic frequency. With low frequency phase-locking units an excitator...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90286-9
更新日期：1976-08-13 00:00:00
abstract：:Superfusion of rat hypothalamic slices with 10(-4) M N-methyl-D-aspartic acid (NMDA) resulted in increased release of alpha-melanocyte-stimulating hormone (alpha-MSH). Peptide release was blocked by 10(-6) M NG-nitro-L-arginine methyl ester (L-NAME) a specific competitive inhibitor of nitric oxide synthase but not by ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90773-0
更新日期：1994-12-15 00:00:00
abstract：:Histochemical and immunochemical techniques are used to locate 2',3'-cyclic nucleotide-3'-phosphohydrolase (2',3'-cNMP-3'ase) within cells of the vertebrate retina. A new histochemical method is described which links the hydrolysis of 2',3'-cNADP to the formation of a reduced, insoluble tetrazolium formazan. Photorece...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90335-9
更新日期：1983-04-18 00:00:00
abstract：:Rat hippocampal slices were perfused with epidermal growth factor (EGF) at a concentration of 10(-8) M. EGF is a well known mitogen which exhibits neurotrophic action on neurons of the CNS. During extra- and intracellular recordings in the pyramidal cell body layer of the CA1-region no influence of EGF on evoked poten...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90380-6
更新日期：1989-04-10 00:00:00
abstract：:Prostaglandin E2 (PGE2) and proton are typical inflammatory mediators. They play a major role in pain processing and hypersensitivity through activating their cognate receptors expressed in terminals of nociceptive sensory neurons. However, it remains unclear whether there is an interaction between PGE2 receptors and ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.146442
更新日期：2019-12-01 00:00:00
abstract：:Protease-activated receptors (PARs), G-protein-coupled receptors, are widely expressed in various tissues, where they participate in physiological and pathological processes, such as hemostasis, proliferation, tissue repair, and inflammation. Recently, we found that PARs were upregulated in the rat retina following op...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.04.040
更新日期：2005-06-21 00:00:00
abstract：:Rats selectively bred for high or low levels of emotionality represent an important and powerful tool to investigate the role of genetic variables in the occurrence of different anxiety disorders. In the present study, albino rats were selectively bred for differences in defensive freezing behavior in response to cont...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.07.044
更新日期：2008-10-03 00:00:00
abstract：:In this report, using a push-pull perfusion technique, we examined in vivo the effects of exogenous dopamine (DA) on the output of neurochemical substances from the caudate nucleus (CN) of freely behaving rats. Exogenous DA, at concentrations of 10(-5) M, 5 x 10(-5) M and 10(-4) M, in modified Krebs-Ringer phosphate m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90803-2
更新日期：1989-03-06 00:00:00
abstract：:Neurons are distinctive in that they are generally considered to be permanently post-mitotic cells. The oncoprotein p53 is a key regulator in neuronal development, notably in cell proliferation and neuronal death. We hypothesize that p53 maintains the post-mitotic characteristic of differentiated neurons. New lines of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04119-7
更新日期：2003-03-07 00:00:00
abstract：:Results of the preceding paper32 suggest that bulbo-pontine respiration related units (RRU) could be classed into 4 populations according to the relation of their peak firing frequency to the respiratory cycle: one inspiratory (I) and 3 expiratory (E) (early, mid and late). A further study of their spatial distributio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90668-5
更新日期：1976-09-17 00:00:00
abstract：:Following transection of a peripheral nerve in mice, a newly synthesized neurotropic pyrimidine compound, MS-818 was administered intraperitoneally at a dose of 1 mg kg-1 b.wt. day-1. The film model experiments for analyzing the early growth of axonal regeneration suggested that MS-818 activated Schwann cells which mi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01491-1
更新日期：1998-03-23 00:00:00
abstract：:Lesions of the anterior hypothalamus-medial preoptic area (AH-MPOA) impair courtship and copulatory behavior in male Cnemidophorus inornatus, a sexually reproducing species of whiptail lizard, and male-like pseudosexual behaviors in C. uniparens, an all-female species. These results suggest that, since C. inornatus is...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90046-9
更新日期：1994-04-18 00:00:00
abstract：:We investigated the effect of beta-estradiol (E2) on synaptogenesis in the hippocampus using organotypic hippocampal slice cultures and subregional hippocampal neuron cultures. E2 increased the expression of PSD95, a postsynaptic marker, specifically in stratum lucidum of Cornu Ammonis 3 (CA3SL) in cultured hippocampa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.02.093
更新日期：2007-05-30 00:00:00
abstract：:The concentrations of GABA, glutamate, aspartate, glycine, taurine, glutamine, asparagine and alanine were determined in the CSF of 10 Senegalese baboons (Papio papio) following initial ketamine anaesthesia and subsequent administration (4 h later) of different compounds known to alter either inhibitory or excitatory ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90370-b
更新日期：1991-01-04 00:00:00
abstract：:Brevetoxins (PbTx) are potent allosteric enhancers of voltage-gated sodium channel (VGSC) function and are associated with periodic "red tide" blooms. These neurotoxins produce neuronal injury and death in cerebellar granule cells (CGC) following acute exposure. In murine neocortical neurons, brevetoxin induces Ca(2+)...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.10.018
更新日期：2005-01-07 00:00:00
abstract：:The accumulation of acid-labile CO2 was measured in the rat brain at early times after exposure to 30% CO2 in oxygen. In particular, the effect on CO2 accumulation of inhibiting brain carbonic anhydrase with acetazolamide was studied. For 57 rats, a rat head perfusion technique was used which permits control and rapid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90443-6
更新日期：1980-09-15 00:00:00
abstract：:There is a strong link between cognitive impairment and depression, but up to date it is not clear whether cognitive impairment is 'cause' or 'consequence' of depression. Therefore, we here examined the effect of cognitive impairment induced by permanent occlusion of common carotid arteries, a model known as two-vesse...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.09.056
更新日期：2015-01-30 00:00:00
