Monoamine oxidase inhibitors from Gentiana lutea.

Abstract:

:Three monoamine oxidase (MAO) inhibitors were isolated from Gentiana lutea. Their structures were elucidated to be 3-3''linked-(2'-hydroxy-4-O-isoprenylchalcone)-(2'''-hydroxy-4''-O-isoprenyldihydrochalcone) (1), 2-methoxy-3-(1,1'-dimethylallyl)-6a,10a-dihydrobenzo(1,2-c)chroman-6-one and 5-hydroxyflavanone. These compounds, and the hydrolysis product of 1, displayed competitive inhibitory properties against MAO-B which was more effective than MAO-A.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Haraguchi H,Tanaka Y,Kabbash A,Fujioka T,Ishizu T,Yagi A

doi

10.1016/j.phytochem.2004.06.025

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

2255-60

issue

15

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(04)00286-9

journal_volume

65

pub_type

杂志文章
  • Odd-numbered very-long-chain polyunsaturated fatty acids from the dinoflagellate Amphidinium carterae identified by atmospheric pressure chemical ionization liquid chromatography-mass spectrometry.

    abstract::A method is described for the enrichment of odd very-long-chain polyunsaturated fatty acids (VLCPUFAs) by means of RP-HPLC and argentation TLC from total fatty acids of the dinoflagellate A. carterae and their identification as picolinyl esters by means of microbore liquid chromatography-mass spectrometry with atmosph...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.08.021

    authors: Rezanka T,Nedbalová L,Sigler K

    更新日期:2008-11-01 00:00:00

  • Gibberellin oxidase activities in Bradyrhizobium japonicum bacteroids.

    abstract::Bradyrhizobium japonicum bacteroids isolated from root nodules of soybean (Glycine max.) plants converted the gibberellin (GA) precursor [(14)C1]GA12 into several products identified by combined gas chromatography-mass spectrometry as [(14)C1]GA24, [(14)C1]GA9, [(14)C1]GA15, GA9 17-nor-16-one and unidentified products...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.11.013

    authors: Méndez C,Baginsky C,Hedden P,Gong F,Carú M,Rojas MC

    更新日期:2014-02-01 00:00:00

  • Highly glycosylated flavonols with an O-linked branched pentasaccharide from Iberis saxatilis (Brassicaceae).

    abstract::Four flavonol glycosides isolated from non-flowering leafy shoots of Iberis saxatilis (Brassicaceae) were characterised by spectroscopic and chemical methods as saxatilisins A-D, the 3-O-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)[β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside, 3-O-β-D-...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.12.009

    authors: Prescott TA,Kite GC,Porter EA,Veitch NC

    更新日期:2013-04-01 00:00:00

  • Purification, sequencing and characterization of phospholipase D from Indian mustard seeds.

    abstract::Phospholipase D (PLD; E.C. 3.1.4.4) is widespread in plants where it fulfills diverse functions in growth and in the response to stresses. The enzyme occurs in multiple forms that differ in their biochemical properties. In the present paper PLD from medicinally relevant Indian mustard seeds was purified by Ca(2+)-medi...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.05.022

    authors: Khatoon H,Mansfeld J,Schierhorn A,Ulbrich-Hofmann R

    更新日期:2015-09-01 00:00:00

  • Steroidal saponins from the bulbs of Camassia cusickii.

    abstract::Six new steroidal saponins have been isolated from the fresh bulbs of Camassia cusickii. Their structures were determined by spectroscopic analysis and some chemical transformations to be (25R)-5 alpha-spirostan-3 beta,6 alpha-diol (chlorogenin) 6-O-beta-D-glucopyranoside, chlorogenin 6-O-beta-D-glucopyranosyl-(1----2...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(91)80098-l

    authors: Mimaki Y,Sashida Y,Kawashima K

    更新日期:1991-01-01 00:00:00

  • Vacuolar uptake of the phytoalexin medicarpin by the glutathione conjugate pump.

    abstract::We have studied the uptake of [3H]-medicarpin and its glutathione conjugate(s) into vacuolar membrane vesicles from etiolated hypocotyls of mung bean (Vigna radiata). Unconjugated medicarpin is taken up at a low rate in the presence or absence of MgATP. However, [3H]-medicarpin-glutathione conjugate(s), prepared by in...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(97)00031-9

    authors: Li ZS,Alfenito M,Rea PA,Walbot V,Dixon RA

    更新日期:1997-06-01 00:00:00

  • Bisamides from Aglaia edulis.

    abstract::The leaves of Aglaia edulis afforded a new bisamide, aglaiduline, and two new sulfur-containing bisamides, aglaithioduline and aglaidithioduline. Their structures were established from spectroscopic studies. The sulfur-containing amides exhibited slight antiviral activity against herpes simplex virus types 1 and 2. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(99)00378-7

    authors: Saifah E,Suttisri R,Shamsub S,Pengsuparp T,Lipipun V

    更新日期:1999-11-01 00:00:00

  • Sesquiterpenoid glycosides from glandular trichomes of the wild tomato relative Solanum habrochaites.

    abstract::Profiles of terpenoid glycoside metabolites in glandular trichomes of Solanum habrochaites LA1777 leaves were generated using ultrahigh performance liquid chromatography/time-of-flight mass spectrometry with multiplexing of non-selective collision-induced dissociation (CID). Profiling data suggested a diverse group of...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.11.011

    authors: Ekanayaka EA,Li C,Jones AD

    更新日期:2014-02-01 00:00:00

  • Applicability of ISSR and DAMD markers for phyto-molecular characterization and association with some important biochemical traits of Dendrobium nobile, an endangered medicinal orchid.

    abstract::Dendrobium nobile is an important medicinal orchid having profound importance in traditional herbal drug preparations and pharmacopeias worldwide. Due to various anthropogenic pressures the natural populations of this important orchid species are presently facing threats of extinction. In the present study, genetic an...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.06.022

    authors: Bhattacharyya P,Kumaria S,Tandon P

    更新日期:2015-09-01 00:00:00

  • Coumaronochromones and flavanones from Euchresta formosana roots.

    abstract::Four coumaronochromones, formosanatins A-D (-4), and a flavanone, euchrenone a(16), along with four known compounds, euchretins E and G, euchrestaflavanone A, and daidzein, were isolated from the roots of Euchresta formosana. The structures of - were established by spectroscopic analyses. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00017-1

    authors: Lo WL,Chang FR,Hsieh TJ,Wu YC

    更新日期:2002-08-01 00:00:00

  • Vanillin.

    abstract::Vanillin (4-hydroxy-3-methoxybenzaldehyde) is an important flavour and aroma molecule, but is also of interest because of its biogenetic relationship to the phenylpropanoid pathway and to other molecules of physiological significance, notably salicylate. Recent progress towards characterisation of the biosynthesis of ...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9422(03)00149-3

    authors: Walton NJ,Mayer MJ,Narbad A

    更新日期:2003-07-01 00:00:00

  • Cardenolide glycosides from root of Streptocaulon juventas.

    abstract::Six cardenolides were isolated from the anti-tumor active fraction of the 75% ethanol extract of Streptocaulon juventas (Asclepiadaceae), mainly found in southwest of China. These were named 1α, 14β-dihydroxy-5β-card-20 (22)-enolide 3-O-[O-β-D-glucopyranosyl-(1→2)-β-D-digitalopyranoside] (1), acovenosigenin A 3-O-[O-β...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.12.004

    authors: Xue R,Han N,Ye C,Wang HB,Yin J

    更新日期:2013-04-01 00:00:00

  • Ambiguanine A-G, hexahydrobenzophenanthridine alkaloids from Corydalis ambigua var. amurensis.

    abstract::Seven hexahydrobenzophenanthridine-type alkaloids, Ambiguanine A-G, along with eight known alkaloids, were isolated from tubers of Corydalis ambigua var. amurensis. Their structures were elucidated based on extensive spectroscopic analyses, with absolute configurations determined by CD experiments. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.05.013

    authors: Yang ZY,Jiang BH,Teng FK,Han N,Liu ZH,Zhou JJ,Wang Y,Guo DA,Yin J

    更新日期:2014-09-01 00:00:00

  • Secoiridoids from Gentiana siphonantha.

    abstract::Repeated fractionations of the methanol extract of the subterranean parts (rhizomes and roots) of Gentiana siphonantha afforded two new and five known secoiridoids, in addition to the widespread plant constituents beta-sitiosterol, daucosterol and oleanolic acid. The structures of the new acyl secoiridoid glycosides w...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(97)00225-2

    authors: Tan RX,Kong LD

    更新日期:1997-11-01 00:00:00

  • Iridoid glycosides and cucurbitacin glycoside from Neopicrorhiza scrophulariiflora.

    abstract::Three iridoid glycosides, picrorosides A (1), B (2) and C (3), and a cucurbitacin glycoside, scrophoside A (4), were isolated from the rhizomes of Neopicrorhiza scrophulariiflora (Scrophulariaceae), along with two known iridoid glycosides, picrosides I (5) and II (6), and three known cucurbitacin glycosides (7-9). The...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.09.015

    authors: Kim IH,Uchiyama N,Kawahara N,Goda Y

    更新日期:2006-12-01 00:00:00

  • Pyranonaphthoquinone and anthraquinone derivatives from Ventilago harmandiana and their potent anti-inflammatory activity.

    abstract::The chemical study on the heartwoods extract of Ventilago harmandiana (Rhamnaceae) resulted in the isolation of ten previously undescribed pyranonaphthoquinones (ventilanones A-J), an undescribed anthraquinone (ventilanone K), together with eight known anthraquinone derivatives. Their structures were elucidated by ext...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.112182

    authors: Panthong K,Hongthong S,Kuhakarn C,Piyachaturawat P,Suksen K,Panthong A,Chiranthanut N,Kongsaeree P,Prabpai S,Nuntasaen N,Reutrakul V

    更新日期:2020-01-01 00:00:00

  • Cuticular waxes from potato (Solanum tuberosum) leaves.

    abstract::The qualitative and quantitative compositions of leaf cuticular waxes from potato (Solanum tuberosum) varieties were studied. The principal components of the waxes were very long chain n-alkanes, 2-methylalkanes and 3-methylalkanes (3.1-4.6 microg cm(-2)), primary alcohols (0.3-0.7 microg cm(-2)), fatty acids (0.3-0.6...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.10.012

    authors: Szafranek BM,Synak EE

    更新日期:2006-01-01 00:00:00

  • Chemical and genetic diversity of Ligularia vellerea in Yunnan, China.

    abstract::Intra-specific diversity in Liularia vellerea growing in the northwestern to central Yunnan province of China was studied by chemical and genetic approaches. Samples collected in the Jianchuan, Lijiang, and Zhongdian areas contained 6,15-dioxygenated furanoeremophilanes as their major components (type A); whereas samp...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2007.12.001

    authors: Tori M,Nakamizo H,Mihara K,Sato M,Okamoto Y,Nakashima K,Tanaka M,Saito Y,Sono M,Gong X,Shen Y,Hanai R,Kuroda C

    更新日期:2008-03-01 00:00:00

  • A role for a Hevea latex lectin-like protein in mediating rubber particle aggregation and latex coagulation.

    abstract::An in vitro aggregation of washed lutoid membrane and rubber particles, respectively, prepared from the bottom (lutoid) fraction and rubber layer of centrifuged fresh latex, leading to the formation of rubber coagulum necessary for a latex coagulation was demonstrated. A Triton X-100 extract of washed lutoid membrane ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2007.08.019

    authors: Wititsuwannakul R,Pasitkul P,Kanokwiroon K,Wititsuwannakul D

    更新日期:2008-01-01 00:00:00

  • Xanthones from a microfungus of the genus Xylaria.

    abstract::Chemical investigations of a microfungus Xylaria sp. isolated from the Australian rainforest tree Glochidion ferdinandi have afforded two new natural products, 2-hydroxy-6-methyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (1) and 2-hydroxy-6-hydroxymethyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (2). Compound ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2004.07.019

    authors: Healy PC,Hocking A,Tran-Dinh N,Pitt JI,Shivas RG,Mitchell JK,Kotiw M,Davis RA

    更新日期:2004-08-01 00:00:00

  • Enantioselective accumulation of (--)-pinoresinol through O-demethylation of (+/-)-eudesmin by Aspergillus niger.

    abstract::Microbial transformation of (+/-)-eudesmin by Aspergillus niger was investigated. Enantioselective accumulation of (--)-pinoresinol was shown through O-demethylation of (+/-)-eudesmin. This fungus O- demethylated both enantiomers of eudesmin, but the conversion rates for each enantiomer were clearly different. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(96)00754-6

    authors: Kasahara H,Miyazawa M,Kameoka H

    更新日期:1997-04-01 00:00:00

  • A potent bidirectional promoter from the monocot cereal Eleusine coracana.

    abstract::Ragi bifunctional α-amylase-trypsin inhibitor (RBI) of Eleusine coracana (L.) Gaertn. (finger millet) simultaneously inhibits α-amylase and trypsin. In continuation of previous work on the cloning, expression and characterization of RBI, a bidirectional promoter from finger millet was explored on the basis of experime...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2016.07.009

    authors: Sen S,Dutta SK

    更新日期:2016-09-01 00:00:00

  • Glycolipid composition of Hevea brasiliensis latex.

    abstract::Glycolipids of fresh latex from three clones of Hevea brasiliensis were characterized and quantified by HPLC/ESI-MS. Their fatty acyl and sterol components were further confirmed by GC/MS after saponification. The four detected glycolipid classes were steryl glucosides (SG), esterified steryl glucosides (ESG), monogal...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.04.023

    authors: Liengprayoon S,Sriroth K,Dubreucq E,Vaysse L

    更新日期:2011-10-01 00:00:00

  • Characterization and oxidative in vitro cross-linking of an extensin-like protein and a proline-rich protein purified from chickpea cell walls.

    abstract::Two cell wall proteins from chickpea, known to be rapidly insolubilised by an elicitor-stimulated oxidative burst in-vivo, were purified from suspension cells. N-terminal protein sequencing revealed them as a proline-rich protein and an extensin-like protein. Oxidative cross-linking could be modelled in an in vitro sy...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(99)00463-x

    authors: Otte O,Barz W

    更新日期:2000-01-01 00:00:00

  • A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark.

    abstract::Along with three known drimanes, polygodial. 1-beta-(p-methoxycinnamoyl) polygodial and mukaadial, the sesquiterpene drimane named drimanial was isolated from the bark of Drimys winteri (Winteraceae). Its structure was elucidated based on spectroscopic evidence. Drimanial exhibited antinociceptive action against aceti...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00515-x

    authors: Malheiros A,Filho VC,Schmitt CB,Santos ARS,Scheidt C,Calixto JB,Monache FD,Yunes RA

    更新日期:2001-05-01 00:00:00

  • Cytochrome P450 enzymes: A driving force of plant diterpene diversity.

    abstract::In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The modifications introduced by CYPs include hydroxylations, sequential oxidations at one position and ring rearrangements and closures. These reactions sign...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2018.12.003

    authors: Bathe U,Tissier A

    更新日期:2019-05-01 00:00:00

  • Purification and partial sequences of Aralia cordata cinnamyl alcohol dehydrogenase.

    abstract::Cinnamyl alcohol dehydrogenase (CAD) (EC 1.1.1.195) from a dicot, Aralia cordata, was purified to homogeneity and its properties were characterized. The enzyme shows a preference for cinnamyl alcohols and cinnamyl aldehydes as substrates. The M(r) is estimated at 72,000. The enzyme is composed of two heterogeneous sub...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)95137-9

    authors: Hibino T,Shibata D,Umezawa T,Higuchi T

    更新日期:1993-02-01 00:00:00

  • Withanolides from aerial parts of Nicandra physalodes.

    abstract::Twenty withanolides, including previously unknown nicanlodes A-M, were isolated from aerial parts of Nicandra physalodes. Their structural elucidations were unambiguously achieved through interpretation of extensive spectroscopic data (NMR and HRMS) and by comparison with literature data. Nicanlodes A and B have an un...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.02.009

    authors: Yu MY,Zhao GT,Liu JQ,Khan A,Peng XR,Zhou L,Dong JR,Li HZ,Qiu MH

    更新日期:2017-05-01 00:00:00

  • Microbial oligosaccharides differentially induce volatiles and signalling components in Medicago truncatula.

    abstract::Plants perceive biotic stimuli by recognising a multitude of different signalling compounds originating from the interacting organisms. Some of these substances represent pathogen-associated molecular patterns, which act as general elicitors of defence reactions. But also beneficial microorganisms like rhizobia take a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.04.019

    authors: Leitner M,Kaiser R,Rasmussen MO,Driguez H,Boland W,Mithöfer A

    更新日期:2008-07-01 00:00:00

  • Monoterpene biosynthesis in the liverwort Conocephalum conicum: demonstration of sabinene synthase and bornyl diphosphate synthase.

    abstract::(-)-Sabinene is the major monoterpene produced by a European strain of the liverwort Conocephalum conicum. A cell-free extract from in vitro cultured plants catalysed the cyclization of geranyl diphosphate to sabinene. The responsible monoterpene cyclase was partially purified and characterized as an operationally sol...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(97)00741-3

    authors: Adam KP,Croteau R

    更新日期:1998-09-01 00:00:00