Abstract:
:To provide longitudinal data on the treatment of acute mania with neuroleptics in a routine setting, 125 consecutively admitted manic patients were examined. Out of the 125 patients, 111 (89%) were primarily treated with neuroleptics during the index episode, and a substantial use of drug combinations was observed. Of the 111 patients, 27% were still hospitalized and in a manic state after 10 weeks. Our results indicate that treatment under routine conditions is an outcome variable which is determined by the severity and persistence of the manic symptoms. If typical neuroleptics are used as first choice antimanic agents, dosages can be minimized by the concomitant use of a benzodiazepine. In non-responders, a mere shift from one neuroleptic to another does not seem rational, so to improve outcome, a mood stabilizer should be added.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Licht RW,Gouliaev G,Vestergaard P,Dybbro J,Lund H,Merinder Ldoi
10.1016/0165-0327(94)90016-7subject
Has Abstractpub_date
1994-11-01 00:00:00pages
179-85issue
3eissn
0165-0327issn
1573-2517pii
0165-0327(94)90016-7journal_volume
32pub_type
杂志文章abstract::After one accommodation night, sleep EEG recordings were performed during three consecutive nights in ten drug-free inpatients presenting generalized anxiety disorder (GAD) with significant depression, compared with a age- and sex-matched group of patients with GAD and a group of primary major depressive disorder (MDD...
journal_title:Journal of affective disorders
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doi:10.1016/0165-0327(88)90078-x
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Late-life depressive disorder is becoming an important issue in health economics in the world, as it has been reported to be one of major risk factors for incidence of dementia. Identification of predictive markers associated with depression in later life is therefore of high priority in public health. The a...
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abstract:BACKGROUND:Cognitive remediation is accepted as an important therapeutic intervention in schizophrenia, but few studies provide data on whether the benefits extend to affective disorders. OBJECTIVES:To review quantitatively studies of cognitive remediation with samples that included cases of schizoaffective disorder, ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
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更新日期:2012-12-15 00:00:00
abstract::Tricyclic antidepressants with clinically significant amounts of anticholinergic activity can adversely affect memory and cognitive functioning. The study evaluated the effect of two non-anticholinergic antidepressants, fluoxetine and trazodone, on immediate and short-term memory in clinically depressed outpatients. T...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Deficits in social cognition, e.g. theory of mind (ToM) represent core characteristics involved in the etiology of psychopathological symptoms and an important predictor of social competence. In bipolar affective disorder, evidence for ToM deficits is scant, although brain imaging studies and impairments in ...
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journal_title:Journal of affective disorders
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更新日期:2015-07-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00084-0
更新日期:1997-10-01 00:00:00
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
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更新日期:2004-04-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
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更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Recent resting-state fMRI studies on major depressive disorder (MDD) have found altered temporal correlation between low-frequency oscillations (LFOs). However, changes on the amplitudes of these LFOs remain largely unknown. METHODS:Twenty-two medication-naive, first-episode patients with MDD and 19 age-, s...
journal_title:Journal of affective disorders
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doi:10.1016/j.jad.2012.10.001
更新日期:2013-04-25 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.01.020
更新日期:2015-05-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.10.033
更新日期:2016-01-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/0165-0327(89)90037-2
更新日期:1989-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.12.225
更新日期:2008-07-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(82)90022-2
更新日期:1982-03-01 00:00:00
abstract::Nine-month outcome data of a randomized controlled out-patient trial of cognitive-behavioural treatment (CBT) for children and adolescents with depression are presented. CBT was compared with a non-focussed intervention (NFI) in 56 subjects. At 9 months after thr termination of the trial, 21 children (37.5%) fulfilled...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-0327(96)00054-7
更新日期:1996-09-09 00:00:00
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journal_title:Journal of affective disorders
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更新日期:2021-02-15 00:00:00
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更新日期:2021-02-15 00:00:00
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更新日期:1991-11-01 00:00:00
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更新日期:2016-01-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.11.031
更新日期:2012-02-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(90)90056-e
更新日期:1990-12-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.09.023
更新日期:2017-01-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2013.06.039
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to evaluate the effects of vitamin D supplementation on depression severity, serum 25(OH)D, and some neurotransmitters in patie...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.029
更新日期:2020-05-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.01.005
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:This study assesses depression among primary care patients, the relationship between depression and functioning, and how frequently depressed individuals receive mental health treatment. METHODS:Two hundred and thirteen participants completed a diagnostic interview and measures of functional impairment and ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00191-8
更新日期:1999-09-01 00:00:00