Abstract：
BACKGROUND:This study assesses depression among primary care patients, the relationship between depression and functioning, and how frequently depressed individuals receive mental health treatment. METHODS:Two hundred and thirteen participants completed a diagnostic interview and measures of functional impairment and service utilization. RESULTS:Sixty-two clinic patients were depressed, and depressed individuals experienced significant functional impairment even after controlling for comorbid anxiety disorders and medical problems. However, less than 40% of depressed individuals were receiving treatment for depression. Severity of impairment was related to likelihood of receiving mental health services. LIMITATIONS:Several factors to consider when evaluating this study are the cross-sectional design, use of self-report data, and lack of random sampling. CONCLUSIONS:These results show that depression has a unique and significant impact on the functioning of primary care patients, and emphasize the need for identification of depressive disorders in primary care.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
McQuaid JR,Stein MB,Laffaye C,McCahill MEdoi
10.1016/s0165-0327(98)00191-8subject
Has Abstractpub_date
1999-09-01 00:00:00pages
1-10issue
1eissn
0165-0327issn
1573-2517pii
S0165-0327(98)00191-8journal_volume
55pub_type
杂志文章abstract：BACKGROUND:Maternal postnatal depression (PND) has been associated with adverse outcomes in young children, but an association with longer-term psychiatric disorder has not been demonstrated. We present the preliminary findings of a 13-year longitudinal study. METHODS:In the course of a prospective longitudinal study,...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2006.06.010
更新日期：2007-01-01 00:00:00
abstract：:This article describes an analysis of spouse concordance for major depression and for other depressive experiences. Respondents to a community survey of married men and women (N = 586 couples) completed a modified version of the Diagnostic Interview Schedule from which diagnoses of major depression and dysthymia were ...
journal_title：Journal of affective disorders
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doi：10.1016/0165-0327(93)90096-3
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Childhood maltreatment is an established distal risk factor for later emotional problems, although research suggests this relationship is mediated by proximal factors. However, it is unclear if different forms of childhood maltreatment are related to unique emotion regulation strategies. In this study, we ex...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2014.11.028
更新日期：2015-03-15 00:00:00
abstract：BACKGROUND:Smaller hippocampus volume represents a consistent finding in major depression (MDD). Hippocampal neuroplasticity due to chronic stress might have differential effect on hippocampal subfields. We investigated the effects of the rs1360780 polymorphism of the hypothalamic-pituitary-axis related gene FKBP5 in c...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.04.054
更新日期：2019-06-01 00:00:00
abstract：:Seventy dementia patients in hospital and two control groups comprising 50 dementia sufferers in the community and 50 mentally fit elderly people, were investigated to determine which social factors such as life events were associated with the presence of anxiety symptoms. Very high levels of social contact, problems ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(95)00094-1
更新日期：1996-07-29 00:00:00
abstract：BACKGROUND:Antenatal depressive and anxiety symptoms are common and may persist over time after delivery, with negative consequences on the mothers and their children. Evidence on the efficacy of psychological and pharmacological interventions during pregnancy aimed at preventing post-partum depression is controversial...
journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章
doi：10.1016/j.jad.2018.12.028
更新日期：2019-03-01 00:00:00
abstract：UNLABELLED:Biased inhibitory processing, frequency and valence of automatic thoughts, and inability to use positive schemas to regulate negative mood are cognitive factors linked to depression. These processes may underlie the established link between adaptive cognitive coping strategies (acceptance and positive refram...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.05.014
更新日期：2013-09-25 00:00:00
abstract：BACKGROUND:The experience of social exclusion (ostracism) is linked to the etiology and maintenance of depression. Most individuals experience emotional stress in states of social exclusion. Insecurely attached individuals, especially with an unresolved trauma, show maladaptive coping in response to social stress. The ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.12.030
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:The time between anaesthetic induction and ECT stimulus administration has been hypothesised to significantly impact ictal EEG quality. In this study, our aim was to examine the effect of the time interval between anaesthetic induction and the ECT stimulus for ictal seizure quality in ECT sessions utilising ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.04.027
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to evaluate the effects of vitamin D supplementation on depression severity, serum 25(OH)D, and some neurotransmitters in patie...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.03.029
更新日期：2020-05-15 00:00:00
abstract：BACKGROUND:We tested if duration and intensity of episodes in treatment-resistant affectively ill patients were related to cerebrospinal fluid (CSF) concentrations of monoamine metabolites. METHOD:In retrospective life charts were recorded every previous episode of 37 patients with severe treatment-refractory affectiv...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(02)00011-3
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Depression is characterized by gender-specific distinctions, with women being affected more often than men. The Patient Health Questionnaire-9 (PHQ-9) is frequently used to assess depression in primary healthcare. Previous research has yielded heterogeneous findings on the factor structure, and little is kno...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2014.08.053
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Previous epidemiological and clinical studies have reported gender differences in prevalence and clinical features of generalized anxiety disorder (GAD). Such gender differences in clinical phenomenology suggest that the underlying neural circuitry of GAD could also be different in males and females. This st...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.10.049
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:We investigated whether melancholic and non-melancholic Japanese depressive patients differed in regard to a personality feature, interpersonal sensitivity, as measured by the Interpersonal Sensitivity Measure (IPSM). METHODS:In addition to 154 normal controls, 66 remitted melancholic patients and 55 remitt...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(00)00222-6
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:The priority processing of peripherally presented affective stimuli was recently shown in healthy individuals to divert attentional resources dedicated to foveal processing. Here we investigated the influence of sub-clinical levels of anxiety and depression on this bias. METHODS:Eighty-four participants wer...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.05.051
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:The relative importance of individual and country-level factors influencing access to diagnosis and treatment for depression across the world is fairly unknown. METHODS:We analysed cross-national data from the WHO World Health Surveys. Depression diagnosis and access to health care were ascertained using a ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.02.092
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Genetic studies have been consistent that bipolar disorder type I (BPI) runs in families and that this familial aggregation is strongly influenced by genes. In a preliminary study, we proved that anxiety trait meets endophenotype criteria for BPI. METHODS:We assessed 619 individuals from the Central Valley ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.12.019
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:In order to experimentally asses the role of socio-emotional problems in Eating Disorder (ED) psychopathology, we have measured affective states and ED-related attitudes in response to an acute psychosocial stress and their relationships with interpersonal sensitivity in people with Anorexia Nervosa (AN) and...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.05.051
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To explore the alterations and value of brain entropy (BEN) in major depressive disorder (MDD). METHODS:85 MDD patients and 45 matched normal controls were recruited. MDD was diagnosed based on Diagnostic and Statistical Manual of Mental Disorders, 4th ed (DSM-IV). Symptoms of depression were assessed using ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.09.067
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:While depression is associated with decreased self-worth, less is known about how depression relates to the degree of perceived unity of the self over time (CI; continuous identity) and appraisal of past and future selves (temporal self-appraisal). In Study 1, we examined the relationship between depression ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.10.033
更新日期：2017-01-15 00:00:00
abstract：BACKGROUND:Social Anxiety Disorder (SAD) is the second most prevalent psychiatric condition in the US. Because of the inherent nature of SAD, it may cause impairments in workplace functioning, particularly compared to other anxiety disorders that do not necessarily lead to social impairments. In this study, we compared...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.09.024
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:More than 50% of individuals with bipolar disorder (BD) do not reach full psychosocial functioning, even during periods of euthymia. It has been suggested that history of psychotic symptoms is one of the factors which are associated with a worse functional outcome. The objective was to compare psychosocial f...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.12.094
更新日期：2018-03-15 00:00:00
abstract：BACKGROUND:Intermediate cognitive phenotypes (ICPs) are measurable and quantifiable states that may be objectively assessed in a standardized method, and can be integrated into association studies, including genetic, biochemical, clinical, and imaging based correlates. The present study used neuropsychological measures...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.08.018
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Sympathetic nervous function abnormalities have long been suggested to be a possible etiology of panic disorder (PD). Catechol-O-methyltransferase (COMT) affects sympathetic activities, and the COMT Val(158)Met polymorphism has been suggested to be related to PD. The authors examined the relationship between...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.10.008
更新日期：2010-06-01 00:00:00
abstract：:A possible role for somatostatin in affective disorders is suggested by its low concentration in cerebrospinal fluid of patients with depression. Therefore, we studied the regional effects of antidepressant drugs and antimanic agents on somatostatin concentrations in rat brain. Repeated, but not acute, administration ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(92)90078-k
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:Anxiety and depression are common during pregnancy and associated with adverse outcomes for the mother and infant if left untreated. Despite the need to improve treatment accessibility and uptake in this population, no studies have investigated internet-delivered cognitive behavioural therapy (iCBT) for ante...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2018.09.057
更新日期：2019-01-15 00:00:00
abstract：BACKGROUND:Prevention of recurrence is a challenge in the management of major depressive disorder (MDD). The long-term effects of Preventive Cognitive Therapy (PCT) in preventing recurrence in MDD are not known. METHODS:A RCT comparing the addition of PCT to Treatment As Usual (TAU), versus TAU including patients with...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2015.06.048
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:The purpose of the current study was to examine the factorial dimensions underlying Beck Depression Inventory-II (BDI-II) in a large ethnically and economically diverse sample of postpartum women and to assess their relative contribution in differentiating clinical diagnoses in a subsample of depressed women...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.01.039
更新日期：2013-07-01 00:00:00
abstract：:Daytime plasma cortisol levels in four rapid cycling bipolar affective disorder patients were measured longitudinally over multiple affective episodes, and changes in levels with mood state assessed for each individual patient. While three of the four patients had, as expected, increased cortisol levels during depress...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(87)90054-1
更新日期：1987-01-01 00:00:00
abstract：:Background Childhood maltreatment (CM) significantly increases the risk of adulthood psychopathology. Interplay between susceptible genetic variations and CM contributes to the occurrence of depression. This review aims to systematically synthesize the relationships between genetic variations and depression among thos...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2020.06.055
更新日期：2020-11-01 00:00:00
