Cultural links between Salerno and Montecassino.

abstract：BACKGROUND/AIMS:Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis. Mainly reported in proximal regions of the kidney, EMT is now recognized as a key c...

journal_title：American journal of nephrology

authors： Hills CE,Squires PE

更新日期：2010-01-01 00:00:00

abstract：:We have demonstrated considerable variability in the volumes of different glomeruli in given individuals (individual glomerular volume: IGV) in a stereologic study of kidneys at forensic autopsy performed to investigate sudden or unexpected death in people without manifest kidney disease. We review some important asso...

journal_title：American journal of nephrology

authors： Hoy WE,Hughson MD,Diouf B,Zimanyi M,Samuel T,McNamara BJ,Douglas-Denton RN,Holden L,Mott SA,Bertram JF

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:The association between chronic kidney disease (CKD) awareness and healthy behaviors is unknown. We examined whether CKD self-recognition is associated with healthy behaviors and achieving risk-reduction targets known to decrease risk of cardiovascular morbidity and CKD progression. METHODS:CKD awarene...

journal_title：American journal of nephrology

authors： Tuot DS,Plantinga LC,Judd SE,Muntner P,Hsu CY,Warnock DG,Gutiérrez OM,Safford M,Powe NR,McClellan WM,REGARDS Investigators.

更新日期：2013-01-01 00:00:00

abstract：:Historically, stroke, heart failure and renal insufficiency were seen as the major complications of untreated hypertension. More recently, it has become evident that coronary heart disease is probably the most common outcome of this condition. Unlike the other complications of hypertension, coronary events have not be...

journal_title：American journal of nephrology

authors： Weber MA

更新日期：1996-01-01 00:00:00

abstract：:The effects of cisplatin (5 mg/kg BW given intraperitoneally) on renal concentration mechanism were evaluated initially by clearance studies in rats 5-7 days after cisplatin administration and compared to normal rats. During hypotonic saline infusion, cisplatin rats showed a lower inulin clearance (0.56 +/- 0.07 vs. 1...

journal_title：American journal of nephrology

authors： Seguro AC,Shimizu MH,Kudo LH,dos Santos Rocha A

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The outcome-predictability of baseline and instantaneously changing serum calcium in hemodialysis patients has been examined. We investigated the mortality-predictability of time-averaged calcium values to reflect the 'cumulative' effect of calcium burden over time. METHODS:We employed a Cox model using up-...

journal_title：American journal of nephrology

authors： Miller JE,Kovesdy CP,Norris KC,Mehrotra R,Nissenson AR,Kopple JD,Kalantar-Zadeh K

更新日期：2010-01-01 00:00:00

abstract：:A 22-year-old woman presented glomerulonephritis with Schönlein-Henoch-like syndrome and monoclonal abnormality. One month later, she developed a rapidly progressive glomerulonephritis with hypertension and persistent purpura. In the two renal biopsies performed during the first and the second attack, mesangial expans...

journal_title：American journal of nephrology

authors： Orfila C,Meeus F,Bernadet P,Lepert JC,Suc JM

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Kidney failure is believed to have a negative impact on cognitive function, and cognitive impairment is common among maintenance hemodialysis (HD) patients. Previous studies have shown a beneficial effect of kidney transplantation in certain cognitive tests but not across all cognitive domains assessed. But,...

journal_title：American journal of nephrology

authors： Radić J,Ljutić D,Radić M,Kovačić V,Dodig-Ćurković K,Šain M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cystic epithelia in polycystic kidney disease display features similar to malignant cells. Thiazolidinediones have been shown to have anti-neoplastic properties, therefore we tested the hypothesis that pioglitazone reduces cyst formation, improves renal function, and prolongs survival in a mouse model o...

journal_title：American journal of nephrology

authors： Raphael KL,Strait KA,Stricklett PK,Baird BC,Piontek K,Germino GG,Kohan DE

更新日期：2009-01-01 00:00:00

abstract：:Erythropoietin-stimulating agent (ESA) hyporesponsiveness is aggravated by chronic inflammation in maintenance hemodialysis (MHD) patients. Dyslipidemia is prevalent in MHD patients. Statin therapy has been demonstrated to not only be effective in lowering lipid levels, but also numerous pleiotropic effects including ...

journal_title：American journal of nephrology

authors： Chiang CK,Yang SY,Peng YS,Hsu SP,Pai MF,Huang JW,Hung KY,Wu KD

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Detection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic...

journal_title：American journal of nephrology

authors： Lee J,Chu C,Guzman D,Fontil V,Velasquez A,Powe NR,Tuot DS

更新日期：2019-01-01 00:00:00

abstract：:We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and impro...

journal_title：American journal of nephrology

authors： Auguet T,Lorenzo A,Colomer E,Zamora A,García C,Martínez-Vea A,Richart C,Oliver JA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Prolonged use of corticosteroids continues to be the mainstay in the management of most proteinuric glomerulopathies, but is limited by extensive side effects. Alternative medications such as adrenocorticotropic hormone (ACTH) have been recently used to treat refractory glomerulopathies and have shown superi...

journal_title：American journal of nephrology

authors： Shrivastava S,Chen B,Dworkin LD,Malhotra DK,Gong R

更新日期：2020-01-01 00:00:00

abstract：AIM:The relation of ambient temperature (AMT) and relative humidity to systolic blood pressure (SBP), diastolic blood pressure (DBP), body weight (BW), and body weight gain between dialysis sessions (DeltaBW) was examined in hemodialysis patients by Fourier analysis. METHODS AND RESULTS:The authors recruited 144 dialy...

journal_title：American journal of nephrology

authors： Tozawa M,Iseki K,Iseki C,Morita O,Yoshi S,Fukiyama K

更新日期：1999-01-01 00:00:00

abstract：:Two patients with a long-standing history of familial Mediterranean fever were found to have both microscopic hematuria and proteinuria during the acute attacks. Kidney biopsies from both patients revealed diffuse mesangial proliferative glomerulonephritis with intense mesangial IgA and C3 deposits and no evidence of ...

journal_title：American journal of nephrology

authors： Said R,Nasrallah N,Hamzah Y,Tarawneh M,al-Khatib M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Since low-density lipoprotein (LDL) S-homocysteinylation has been recently reported to enhance atherogenicity of lipoprotein, we have investigated the levels of homocysteine (Hcy) linked to LDL in chronic proteinuric patients in which lipid abnormalities highly contribute to the excess of morbidity and morta...

journal_title：American journal of nephrology

authors： Zinellu A,Loriga G,Scanu B,Pisanu E,Sanna M,Deiana L,Satta AE,Carru C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Conditionally immortalized podocytes are valuable research tools but are difficult to efficiently transfect and do not provide graded transgene expression. METHODS:Conditionally immortalized mouse podocyte cell lines were established employing a tetracycline-inducible system. Glomerular cells, isolated from...

journal_title：American journal of nephrology

authors： Kajiyama H,Titus S,Austin CP,Chiotos K,Matsumoto T,Sakairi T,Kopp JB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Living donor nephrectomy can be associated with increases in blood pressure several years following the procedure, but the best method to assess blood pressure during the living donor evaluation process is unclear. METHODS:Living kidney donors underwent casual clinic and ambulatory blood pressure monit...

journal_title：American journal of nephrology

authors： DeLoach SS,Meyers KE,Townsend RR

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Adherence is paramount in treating hypertension; however, no gold standard method is available for non-adherence screening, delineating high-risk patients. An International Classification of Diseases 9th Edition non-adherence diagnostic code (V15.81) has been available for decades; but, its utility is poorly...

journal_title：American journal of nephrology

authors： Gosmanova EO,Molnar MZ,Alrifai A,Lu JL,Streja E,Cushman WC,Kalantar-Zadeh K,Kovesdy CP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Prior studies suggest that certain aspects of the diet related to magnesium intake, such as dietary acid load, protein intake and dietary patterns rich in fruits and vegetables, may impact kidney disease risk. We hypothesized that lower dietary magnesium intake would be prospectively associated with more rap...

journal_title：American journal of nephrology

authors： Rebholz CM,Tin A,Liu Y,Kuczmarski MF,Evans MK,Zonderman AB,Crews DC

更新日期：2016-01-01 00:00:00

abstract：:Idiopathic diffuse crescentic glomerulonephritis without immune deposits is a variant of rapidly progressive glomerulonephritis which can account for up to 40% of crescentic nephritis. The prognosis may depend on both the severity of histological injury at presentation and the efficacy of treatment. Recent advances in...

journal_title：American journal of nephrology

authors： Belghiti D,Levy Y,Rifle G,Ottavioli JN,Rickelynck JP,Wolf C,Chalopin JM,Sobel A

更新日期：1987-01-01 00:00:00

abstract：:Several medical inventors in Europe and North America brought the artificial kidney (hemodialysis) to practical usefulness in the late 1940s, but there were very few early successes. It was used at first for only desperate cases of acute renal failure. Renal authorities in the 'metabolic' tradition favored newly quant...

journal_title：American journal of nephrology

authors： Peitzman SJ

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a critical need for more noninvasive biomarkers to identify nephritis in patients with systemic lupus erythematosus (SLE). Recent studies in a model mouse and an adult SLE patient cohort suggest that anti-basement membrane antibody levels correlate well with lupus activity and kidney injury. Th...

journal_title：American journal of nephrology

authors： Orjuela A,Suwanichkul A,Canter D,Minard CG,Devaraj S,Hicks MJ,Muscal E,Wenderfer SE

更新日期：2015-01-01 00:00:00

abstract：:Accelerated atherosclerosis is both a cause and a consequence of chronic renal failure. Vascular smooth muscle cells (VSMCs) are an important component of atherosclerotic plaques, responsible for promoting plaque stability in advanced lesions. In contrast, VSMC apoptosis has been implicated in a number of deleterious ...

journal_title：American journal of nephrology

authors： Clarke M,Bennett M

更新日期：2006-01-01 00:00:00

abstract：:In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecu...

journal_title：American journal of nephrology

authors： Kinne-Saffran E,Kinne RK

更新日期：1999-01-01 00:00:00

abstract：:Berengario da Carpi was magister of anatomy and surgery at the University of Bologna from 1502 to 1527. Eustachio and Falloppia defined him as 'the restaurator of anatomy'. He was a great surgeon, anatomist and physician of illustrious patients including Lorenzo II dei Medici, Giovanni dalle Bande Nere, Galeazzo Palla...

journal_title：American journal of nephrology

authors： De Santo NG,Bisaccia C,De Santo LS,De Santo RM,Di Leo VA,Papalia T,Cirillo M,Touwaide A

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a prevalent condition; however, little is known about healthcare resource utilization (HRU) by CKD patients. METHODS:This analysis included NHANES participants aged > or =18 years, with serum creatinine, urine protein, and hemoglobin measurements. We assessed the association ...

journal_title：American journal of nephrology

authors： Alexander M,Bradbury BD,Kewalramani R,Barlev A,Mohanty SA,Globe D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:In autosomal dominant polycystic kidney disease, renoprotective treatment with a vasopressin V2 receptor antagonist (V2RA) is given in a fixed dose (FD). Disease progression and drug habituation could diminish treatment efficacy. We investigated whether the renoprotective effect of the V2RA can be improved b...

journal_title：American journal of nephrology

authors： Zittema D,Versteeg IB,Gansevoort RT,van Goor H,de Heer E,Veraar KA,Peters DJ,Meijer E

更新日期：2016-01-01 00:00:00

abstract：:The relationship between abnormalities in nocturnal penile tumescence (NPT) and autonomic function, measured by the Valsalva maneuver, was evaluated in 25 uremic patients and 22 normal subjects. NPT in uremic patients (45 +/- 6.8 min/night) was lower (p less than 0.01) than in normals (85 +/- 10.4 min/night). Valsalva...

journal_title：American journal of nephrology

authors： Campese VM,Procci WR,Levitan D,Romoff MS,Goldstein DA,Massry SG

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs frequently in the intensive care unit. A primary cause is renal ischemia/reperfusion (I/R) injury, during which excess reactive oxygen species (ROS) are produced. ROS subsequently damage renal cells, leading to the development of AKI. Here, we investigated whether renal I/R i...

journal_title：American journal of nephrology

authors： Yamamoto S,Hagiwara S,Hidaka S,Shingu C,Goto K,Kashima K,Noguchi T

更新日期：2011-01-01 00:00:00