Abstract:
:The human homeobox gene HLX1 appears to be involved in hemopoietic development and may represent a candidate gene for various developmental or hemopoietic disorders. We have isolated genomic clones for the gene, determined its intron-exon organization, and confirmed its map location on chromosome 1q41-q42. The transcription initiation sites of HLX1 were identified, and DNA sequences upstream of these sites were established. Finally, several differences between the genomic sequence and the published cDNA sequence were noted. Translation based on this revised sequence gives rise to a putative protein with 86.5% homology to the product of the murine Hlx gene.
journal_name
Genomicsjournal_title
Genomicsauthors
Kennedy MA,Rayner JC,Morris CMdoi
10.1006/geno.1994.1394subject
Has Abstractpub_date
1994-07-15 00:00:00pages
348-55issue
2eissn
0888-7543issn
1089-8646pii
S0888-7543(84)71394-2journal_volume
22pub_type
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