Simulation of voltage-sensitive optical signals in three-dimensional slabs of cardiac tissue: application to transillumination and coaxial imaging methods.

abstract：:Fluorescence diffuse optical tomography (fDOT) provides 3D images of fluorescence distributions in biological tissue, which represent molecular and cellular processes. The image reconstruction problem is highly ill-posed and requires regularisation techniques to stabilise and find meaningful solutions. Quadratic regul...

journal_title：Physics in medicine and biology

authors： Correia T,Koch M,Ale A,Ntziachristos V,Arridge S

更新日期：2016-02-21 00:00:00

abstract：:The implementation of two algorithms for calculating dose distributions for radiation therapy treatment planning of intermediate energy proton beams is described. A pencil kernel algorithm and a depth penetration algorithm have been incorporated into a commercial three dimensional treatment planning system (Helax-TMS,...

journal_title：Physics in medicine and biology

authors： Russell KR,Isacsson U,Saxner M,Ahnesjö A,Montelius A,Grusell E,Dahlgren CV,Lorin S,Glimelius B

更新日期：2000-01-01 00:00:00

abstract：:We propose a retrospective respiratory gating algorithm to generate dynamic CT studies. To this end, we compared three different methods of extracting the respiratory signal from the projections of small-animal cone-beam computed tomography (CBCT) scanners. Given a set of frames acquired from a certain axial angle, su...

journal_title：Physics in medicine and biology

authors： Chavarrías C,Vaquero JJ,Sisniega A,Rodríguez-Ruano A,Soto-Montenegro ML,García-Barreno P,Desco M

更新日期：2008-09-07 00:00:00

abstract：:The weak absorption of shortwave infrared light by skin tissues between 700 and 1500 nm offers an important window for diagnosis by optical means. The strong scattering of shortwave infrared light by the skin, however, presents a challenge to the modelling of light propagation through the skin and the understanding of...

journal_title：Physics in medicine and biology

authors： Du Y,Hu XH,Cariveau M,Ma X,Kalmus GW,Lu JQ

更新日期：2001-01-01 00:00:00

abstract：:Digital phantoms continue to play a significant role in modeling and characterizing medical imaging. The currently available XCAT phantom incorporates both the flexibility of mathematical phantoms and the realistic nature of voxelized phantoms. This phantom generates images based on a regular breathing pattern and can...

journal_title：Physics in medicine and biology

authors： Mishra P,St James S,Segars WP,Berbeco RI,Lewis JH

更新日期：2012-06-07 00:00:00

abstract：:Beam tracking with scanned carbon ion radiotherapy achieves highly conformal target dose by steering carbon pencil beams to follow moving tumors using real-time magnetic deflection and range modulation. The purpose of this study was to evaluate the robustness of target dose coverage from beam tracking in light of posi...

journal_title：Physics in medicine and biology

authors： Eley JG,Newhauser WD,Richter D,Lüchtenborg R,Saito N,Bert C

更新日期：2015-02-21 00:00:00

abstract：:This study investigated the temperature elevation in the eye of anatomically based human head models for plane-wave exposures. The finite-difference time-domain method is used for analyzing electromagnetic absorption and temperature elevation. The eyes in the anatomic models have average dimensions and weight. Computa...

journal_title：Physics in medicine and biology

authors： Hirata A,Watanabe S,Fujiwara O,Kojima M,Sasaki K,Shiozawa T

更新日期：2007-11-07 00:00:00

abstract：:A cost-effective method employing polysulphone, nalidixic acid, 8-methoxypsoralen and phenothiazine as UV dosimeters is presented for evaluating the UV spectrum. The exposure measured by each dosimeter is a function of the source spectrum and the spectral response of the material. Each material has a different spectra...

journal_title：Physics in medicine and biology

authors： Parisi AV,Wong JC,Moore GI

更新日期：1997-01-01 00:00:00

abstract：:In medical imaging different techniques have been developed to gain information from inside a tissue. Optoacoustics is a method to generate tomography pictures of tissue using Q-switched laser pulses. Due to thermal and pressure confinement, a short light pulse generates a pressure distribution inside tissue, which mi...

journal_title：Physics in medicine and biology

authors： Köstli KP,Frenz M,Bebie H,Weber HP

更新日期：2001-07-01 00:00:00

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:Delivering accurate radiation dose to blood specimens during biological irradiations is essential in quantifying damage of ionizing radiation. To estimate dose to blood samples as accurately as possible, pieces of EBT2 model GAFCHROMIC™ film were placed within an approximately 10 mm finely ground rice layer that was u...

journal_title：Physics in medicine and biology

authors： Aldelaijan S,Nobah A,Alsbeih G,Moftah B,Aldahlawi I,Alzahrany A,Tomic N,Devic S

更新日期：2013-05-21 00:00:00

abstract：:An inverse radiation treatment planning algorithm for Sensus Healthcare's SculpturaTM electronic brachytherapy system has been designed. The algorithm makes use of simulated annealing to optimize the conformation number of the treatment plan. The highly anisotropic dose distributions produced by the SculpturaTM x-ray ...

journal_title：Physics in medicine and biology

authors： Badali DS,Vainer Y,Ellenor CW,Mitchell CR,Fishman K,Soro N,Price R,Funk T

更新日期：2021-01-11 00:00:00

abstract：:It is a challenging problem to resolve and identify drug (or non-specific fluorophore) distribution throughout the whole body of small animals in vivo. In this article, an algorithm of unmixing multispectral fluorescence tomography (MFT) images based on independent component analysis (ICA) is proposed to solve this pr...

journal_title：Physics in medicine and biology

authors： Pu H,Zhang G,He W,Liu F,Guang H,Zhang Y,Bai J,Luo J

更新日期：2014-09-07 00:00:00

abstract：:The Patlak graphical method is widely used in parametric imaging for modeling irreversible radiotracer kinetics in dynamic PET. The net influx rate of radiotracer can be determined from the slope of the Patlak plot. The implementation of the standard Patlak method requires the knowledge of full-time input function fro...

journal_title：Physics in medicine and biology

authors： Zuo Y,Qi J,Wang G

更新日期：2018-08-10 00:00:00

abstract：:Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...

journal_title：Physics in medicine and biology

authors： Bloomfield PM,Myers R,Hume SP,Spinks TJ,Lammertsma AA,Jones T

更新日期：1997-02-01 00:00:00

abstract：:The most advanced delivery technique for proton radiotherapy is active spot scanning. So far, predominantly static targets have been treated with active spot scanning, since mobile targets in combination with dynamic treatment delivery can lead to interplay effects, causing inhomogeneous dose distributions. One way to...

journal_title：Physics in medicine and biology

authors： Knopf AC,Hong TS,Lomax A

更新日期：2011-11-21 00:00:00

abstract：:Silicon diodes have good spatial resolution, which makes them advantageous over ionization chambers for dosimetry in fields with high dose gradients. However, silicon diodes overrespond to low-energy photons, that are more abundant in scatter which increase with large fields and larger depths. We present a cavity-theo...

journal_title：Physics in medicine and biology

authors： Eklund K,Ahnesjö A

更新日期：2009-10-21 00:00:00

abstract：:Recent image guidance developments for preclinical synchrotron microbeam radiotherapy represent a necessary step for future clinical translation of the technique. Image quality can be further improved using x-ray phase contrast, which is readily available at synchrotron facilities. We here describe a methodology for p...

journal_title：Physics in medicine and biology

authors： Pelliccia D,Crosbie JC,Larkin KG

更新日期：2016-08-21 00:00:00

abstract：:Characterization of both malignant and benign lesions in the female breast is presented as the result of a clinical study that involved more than 190 subjects in the framework of the OPTIMAMM European project. All the subjects underwent optical mammography, by means of a multi-wavelength time-resolved mammograph, in t...

journal_title：Physics in medicine and biology

authors： Spinelli L,Torricelli A,Pifferi A,Taroni P,Danesini G,Cubeddu R

更新日期：2005-06-07 00:00:00

abstract：:By the end of 2002, 33 398 patients worldwide had been treated with proton radiotherapy, 10 829 for eye diseases. The dose prediction algorithms used today for ocular proton therapy treatment planning rely on parameterizations of measured proton dose distributions, i.e., broad-beam and pencil-beam techniques, whose pr...

journal_title：Physics in medicine and biology

authors： Newhauser W,Koch N,Hummel S,Ziegler M,Titt U

更新日期：2005-11-21 00:00:00

abstract：:With the addition of variable bed speed capabilities, continuous bed motion (CBM) becomes an acquisition generalization for axial sensitivity modeling and therefore a flexible tool in axial local image quality adjustment. In this paper, we describe the principles behind CBM mode planning and its influence on image rec...

journal_title：Physics in medicine and biology

authors： Panin VY,Smith AM,Hu J,Kehren F,Casey ME

更新日期：2014-10-21 00:00:00

abstract：:This paper describes a neural network (NN) regression model for relative dose computation. The input signal of the NN model includes depths and field sizes and the output is the relative dose, for example, percentage depth dose (%DD) or tissue-air ratio (TAR) in this paper. After a functional link has been created, th...

journal_title：Physics in medicine and biology

authors： Wu X,Zhu Y

更新日期：2000-04-01 00:00:00

abstract：:Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2006-12-07 00:00:00

abstract：:This paper presents a Fourier rebinning algorithm for three-dimensional image reconstruction in PET that incorporates the concept of spectral transfer function. It suggests the need for discarding low-frequency components in the rebinning. It also includes the correction for rebinning efficiency which was evaluated by...

journal_title：Physics in medicine and biology

authors： Tanaka E,Amo Y

更新日期：1998-04-01 00:00:00

abstract：:This study introduces a practical four-dimensional (4D) planning scheme of IMAT using 4D computed tomography (4D CT) for planning tumor tracking with dynamic multileaf beam collimation. We assume that patients can breathe regularly, i.e. the same way as during 4D CT with an unchanged period and amplitude, and that the...

journal_title：Physics in medicine and biology

authors： Niu Y,Betzel GT,Yang X,Gui M,Parke WC,Yi B,Yu CX

更新日期：2017-02-21 00:00:00

abstract：:Kinetic parameters are commonly estimated from dynamically acquired nuclear medicine data by first reconstructing a dynamic sequence of images and subsequently fitting the parameters to time-activity curves generated from regions of interest overlaid upon the image sequence. Biased estimates can result from images rec...

journal_title：Physics in medicine and biology

authors： Huesman RH,Reutter BW,Zeng GL,Gullberg GT

更新日期：1998-04-01 00:00:00

abstract：:Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with wat...

journal_title：Physics in medicine and biology

authors： Cirio R,Garelli E,Schulte R,Amerio S,Boriano A,Bourhaleb F,Coutrakon G,Donetti M,Giordanengo S,Koss P,Madon E,Marchetto F,Nastasi U,Peroni C,Santuari D,Sardo A,Scielzo G,Stasi M,Trevisiol E

更新日期：2004-08-21 00:00:00

abstract：:A finite element thermal model of the head has been developed to calculate temperature rises generated in the brain by radiation from cellular telephones and similar electromagnetic devices. A 1 mm resolution MRI dataset was segmented semiautomatically, assigning each volume element to one of ten tissue types. A finit...

journal_title：Physics in medicine and biology

authors： Wainwright P

更新日期：2000-08-01 00:00:00

abstract：:Gel dosimetry based on magnetic resonance imaging (MRI) has previously been shown to provide verification of calculated dose distributions in soft tissue equivalent homogeneous phantoms. This study demonstrates how measurements of dose distribution can also be achieved in a phantom containing porous, lung-equivalent, ...

journal_title：Physics in medicine and biology

authors： Olberg S,Skretting A,Bruland O,Olsen DR

更新日期：2000-10-01 00:00:00

abstract：:Over the last two years we have evaluated paediatric patient doses in projection radiography derived from exposure level (EL) in computed radiography (CR) in a large university hospital. Entrance surface air kerma (ESAK) for 3501 paediatric examinations was calculated from the EL, which is a dose index parameter relat...

journal_title：Physics in medicine and biology

authors： Vano E,Martinez D,Fernandez JM,Ordiales JM,Prieto C,Floriano A,Ten JI

更新日期：2008-06-21 00:00:00