Butorphanol and morphine: a double-blind comparison of their parenteral analgesic activity.

abstract：:The Meyer-Overton hypothesis predicts that anesthetic potency correlates inversely with lipophilicity; e.g., MAC times the olive oil/gas partition coefficient equals a constant of approximately 1.82 +/- 0.56 atm (mean +/- sd) for conventional inhaled anesthetics. MAC is the minimum alveolar concentration of anesthetic...

journal_title：Anesthesia and analgesia

authors： Won A,Oh I,Liao M,Sonner JM,Harris RA,Laster MJ,Brosnan R,Trudell JR,Eger EI 2nd

更新日期：2006-05-01 00:00:00

abstract：:The management of postoperative nausea and vomiting (PONV) remains a persistent problem. Despite the use of prophylactic antiemetics, breakthrough nausea and vomiting still frequently occur. There have been no published studies comparing dolasetron and ondansetron for the treatment of PONV. This was a prospective, ran...

journal_title：Anesthesia and analgesia

authors： Meyer TA,Roberson CR,Rajab MH,Davis J,McLeskey CH

更新日期：2005-02-01 00:00:00

abstract：:Hemodynamic responses to physostigmine were evaluated in eight patients with coma due to overdose with mainly anticholinergic drugs (AC) and in five patients with coma due to overdose with nonanticholinergic drugs (NAC). After correction of hypovolemia, but before administration of physostigmine, AC patients had signi...

journal_title：Anesthesia and analgesia

authors： Nilsson E,Meretoja OA,Neuvonen P

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Pulse wave analysis (PWA) allows cardiac output (CO) measurement after calibration by transpulmonary thermodilution. A PWA system that does not require previous calibration, the FloTrac/Vigileo (FTV), has been recently developed. We compared determinations of CO made with the FTV to simultaneous measurements...

journal_title：Anesthesia and analgesia

authors： Concha MR,Mertz VF,Cortínez LI,González KA,Butte JM

更新日期：2009-07-01 00:00:00

abstract：INTRODUCTION:Exposure to isoflurane before and during early reperfusion protects against myocardial infarction by activating phosphatidylinositol-3-kinase (PI3K)-mediated signaling. The apoptotic protein, p53, is regulated by PI3K, and inhibition of p53 protects against ischemic injury. We tested the hypothesis that p5...

journal_title：Anesthesia and analgesia

authors： Venkatapuram S,Wang C,Krolikowski JG,Weihrauch D,Kersten JR,Warltier DC,Pratt PF Jr,Pagel PS

更新日期：2006-12-01 00:00:00

abstract：UNLABELLED:We examined the effect of ulinastatin, a protease inhibitor purified from human urine, on neuromuscular block caused by vecuronium. Sixty adult patients were randomly divided into four groups of 15 patients each: ulinastatin-posttetanic count (U-PTC), ulinastatin-train-of-four (U-TOF), control-posttetanic co...

journal_title：Anesthesia and analgesia

authors： Saitoh Y,Fujii Y,Oshima T

更新日期：1999-12-01 00:00:00

abstract：UNLABELLED:In a prospective, randomized, double-blinded study, we evaluated the efficacy of granisetron and ramosetron for preventing postoperative nausea and vomiting (PONV) in major gynecologic surgery. One hundred twenty patients, ASA physical status I or II, aged 23-65 yr, received i.v. granisetron 2.5 mg or ramose...

journal_title：Anesthesia and analgesia

authors： Fujii Y,Saitoh Y,Tanaka H,Toyooka H

更新日期：1999-08-01 00:00:00

abstract：:In in vitro pharmacological experiments, determination of effective concentration values for various anesthetics depends on understanding the exact concentration of the drugs dissolved in physiological solutions. Actual anesthetic concentration may differ from expectations because of drug adsorption, absorption or oth...

journal_title：Anesthesia and analgesia

authors： Suzuki T,Uchida I,Mashimo T

更新日期：2005-02-01 00:00:00

abstract：:Computer simulations for the technique of estimating minimum alveolar anesthetic concentration (MAC) in patients (quantal design) suggest that incremental concentration changes and the number of crossovers affect MAC. We hypothesized that these variables may also apply to estimating MAC in rats (bracketing design). Th...

journal_title：Anesthesia and analgesia

authors： Leon A,Mayzler O,Benifla M,Semionov M,Fuxman Y,Eilig I,Passuga V,Doitchinova MK,Gurevich B,Artru AA,Shapira Y

更新日期：2004-12-01 00:00:00

abstract：:Cardioprotection by anesthetic preconditioning (APC) can be abolished by nitric oxide (NO*) synthase inhibitors or by reactive oxygen species (ROS) scavengers. We previously reported attenuated mitochondrial electron transport (ET) and increased ROS generation during preconditioning sevoflurane exposure as part of the...

journal_title：Anesthesia and analgesia

authors： Riess ML,Kevin LG,McCormick J,Jiang MT,Rhodes SS,Stowe DF

更新日期：2005-01-01 00:00:00

abstract：:A 62-yr-old man presented for a microdirect laryngoscopy and vocal cord fat grafting under jet ventilation. After a prolonged laryngoscopy, the patient developed hypercapnea and upper airway obstruction secondary to traumatic epiglottitis. The placement of a laryngeal mask airway provided ventilation and allowed for d...

journal_title：Anesthesia and analgesia

authors： Kidani DC,Shah NK

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:The purpose of the investigation was to assess the effects of desflurane (DES) on left ventricular heart function during basal barbiturate anesthesia in a closed-pericardium, closed-chest acute swine model. The study was performed in 11 normoventilated adult pigs. Hemodynamic measurements were obtained using...

journal_title：Anesthesia and analgesia

authors： Sundeman H,Haney M,Broomé M,Häggmark S,Johansson G,Winsö O,Biber B

更新日期：1998-09-01 00:00:00

abstract：UNLABELLED:Opioid medication is the mainstay of therapy for severe acute and chronic pain. Unfortunately, the side effects of these medications can affect patient comfort and safety, thus limiting their proven therapeutic potential. Whereas the main analgesic effects of opioids are centrally mediated, many of the commo...

journal_title：Anesthesia and analgesia

authors： Bates JJ,Foss JF,Murphy DB

更新日期：2004-01-01 00:00:00

abstract：:We investigated the appropriateness of the somatosensory evoked potentials (SSEPs) as an objective monitor of sensory blockade of the ulnar nerve by comparing the effects of saline and lidocaine infiltration of the ulnar nerve at the elbow, with and without epinephrine. The four treatments were administered in random ...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Shanks C,Ramseur A,Sloan T

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:There are profound racial and ethnic disparities in obstetric outcomes in the United States, but little is known about disparities in risk of postpartum hemorrhage (PPH). We explored the association of race and ethnicity on the risk of PPH due to uterine atony with sequential adjustment for possible mediatin...

journal_title：Anesthesia and analgesia

authors： Bryant A,Mhyre JM,Leffert LR,Hoban RA,Yakoob MY,Bateman BT

更新日期：2012-11-01 00:00:00

abstract：:Large doses of morphine sulfate have been reported to cause myocardial lactate production and reduction in coronary blood flow in animals. Similar effects with clinical doses in man would significantly alter the management of cardiac patients. Eleven adult patients with significant coronary arterial disease and normal...

journal_title：Anesthesia and analgesia

authors： Sethna DH,Moffitt EA,Gray RJ,Bussell J,Raymond M,Conklin C,Shell WE,Matloff JM

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Implementation of initiatives to increase anesthesia group productivity depends not just on anesthesia groups, but on operating room (OR) nursing administration. OR nursing directors may encourage organizational change based on the needs of their hospitals and nurses. These changes may differ from those that...

journal_title：Anesthesia and analgesia

authors： Masursky D,Dexter F,Nussmeier NA

更新日期：2008-12-01 00:00:00

abstract：UNLABELLED:Children undergoing placement of bilateral myringotomy tubes (BMT) often exhibit pain-related behavior (agitation) in the postanesthesia care unit. We compared the emergence and recovery profiles of pediatric patients who received sevoflurane with or without supplementary intranasal fentanyl for BMT surgery....

journal_title：Anesthesia and analgesia

authors： Finkel JC,Cohen IT,Hannallah RS,Patel KM,Kim MS,Hummer KA,Choi SS,Pena M,Schreiber SB,Zalzal G

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:Postoperative pain management after cardiac surgery has been mainly based on parenteral opioids. However, because opioids have numerous side effects, coadministration of non-opioid analgesics has been introduced as a method of reducing opioid dose. In this prospective, randomized, double-blinded study, we ev...

journal_title：Anesthesia and analgesia

authors： Lahtinen P,Kokki H,Hendolin H,Hakala T,Hynynen M

更新日期：2002-10-01 00:00:00

abstract：:Ketamine given IV in a dose of 2 mg/kg caused a significant reduction in Pao2 in 7 patients spontaneously breathing with an unassisted airway. Under the same conditions, in 7 patients, ketamine (2 mg/kg IV) preceded by diazepam (0.2 mg/kg IV) also caused a reduction in Pao2 not significantly different from that caused...

journal_title：Anesthesia and analgesia

authors： Zsigmond EK,Matsuki A,Kothary SP,Jallad M

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which ...

journal_title：Anesthesia and analgesia

authors： Muffly MK,Chen MI,Claure RE,Drover DR,Efron B,Fitch WL,Hammer GB

更新日期：2017-10-01 00:00:00

abstract：:To determine whether anesthetics alter endothelial eicosanoid release, cultured bovine pulmonary artery endothelial cells were studied during constant flow and pressure perfusion at two oxygen tensions (hypoxia, 50 +/- 2 mm Hg; normoxia, 144 +/- 5 mm Hg; mean +/- SEM) with and without 1% halothane. Endothelialized mic...

journal_title：Anesthesia and analgesia

authors： Barnes SD,Martin LD,Wetzel RC

更新日期：1992-12-01 00:00:00

abstract：UNLABELLED:In the present study, we examined whether preincisional treatment with dextromethorphan (DM) provides preemptive analgesia. Ninety patients scheduled for laparoscopic cholecystectomy were included. Patients receiving chlorpheniramine maleate (CPM) 20 mg via an IM injection 30 min before skin incision were de...

journal_title：Anesthesia and analgesia

authors： Wu CT,Yu JC,Yeh CC,Liu ST,Li CY,Ho ST,Wong CS

更新日期：1999-06-01 00:00:00

abstract：:The antifibrinolytic drug, tranexamic acid, decreases blood loss in adult patients undergoing cardiac surgery. However, its efficacy has not been extensively studied in children. Using a prospective, randomized, double-blind study design, we examined 41 children undergoing repeat sternotomy for repair of congenital he...

journal_title：Anesthesia and analgesia

authors： Reid RW,Zimmerman AA,Laussen PC,Mayer JE,Gorlin JB,Burrows FA

更新日期：1997-05-01 00:00:00

abstract：:We measured arterial plasma concentrations of lidocaine by enzyme immunoassay when 10 ml of 2% lidocaine without epinephrine was injected into the cervical, thoracic, or lumbar epidural spaces in 30 patients. There was no difference in the time courses of plasma levels of lidocaine. Peak concentrations were achieved 1...

journal_title：Anesthesia and analgesia

authors： Mayumi T,Dohi S,Takahashi T

更新日期：1983-06-01 00:00:00

abstract：:Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Khanna AK,Sessler DI

更新日期：2020-07-01 00:00:00

abstract：:We studied the effect of intravenous (IV) thiamylal or ketamine on the increases in serum myoglobin, creatine kinase (CK), and potassium induced by succinylcholine under halothane anesthesia. Ninety patients were divided into three groups. In Group O, succinylcholine (1.0 mg/kg) was administered after an the inhaled i...

journal_title：Anesthesia and analgesia

authors： Noguchi I,Sankawa H,Andou M

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Burnout is a psychological syndrome that results from chronic exposure to job stress. It is defined by a triad of emotional exhaustion, depersonalization, and reduced personal accomplishment. In research, mostly from high-income countries, burnout is common in health care professionals, especially in anesthe...

journal_title：Anesthesia and analgesia

authors： Mumbwe MC,McIsaac D,Jarman A,Bould MD

更新日期：2020-02-01 00:00:00

abstract：:Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of axillary brachial plexus block. Sixty patients scheduled for elective hand and forearm surgery under axillar...

journal_title：Anesthesia and analgesia

authors： Movafegh A,Razazian M,Hajimaohamadi F,Meysamie A

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:Reduction of the inflammatory reaction with the use of heparin coating has been found during and after cardiopulmonary bypass (CPB). The question remains whether this reduced reaction also decreases the magnitude of CPB-induced pulmonary dysfunction. We therefore evaluated the effects of a heparin-coated cir...

journal_title：Anesthesia and analgesia

authors： de Vroege R,van Oeveren W,van Klarenbosch J,Stooker W,Huybregts MA,Hack CE,van Barneveld L,Eijsman L,Wildevuur CR

更新日期：2004-06-01 00:00:00