The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery.

abstract：IMPLICATIONS:We describe a technique of one-lung high-frequency jet ventilation surgery with continuous monitoring of airway pressures that achieves satisfactory operating conditions with less complications than other similar approaches. ...

journal_title：Anesthesia and analgesia

authors： Unzueta MC,Casas I,Merten A,Landeira JM

更新日期：2003-01-01 00:00:00

abstract：IMPLICATIONS:The number of patients supported by ventricular assist devices (VADs) that present for noncardiac surgery is increasing in our institution. Our recent experience with eight such patients is reported, along with a review of the most commonly implanted VADs and the anesthetic implications and considerations ...

journal_title：Anesthesia and analgesia

authors： Stone ME,Soong W,Krol M,Reich DL

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:In this study we sought to determine and compare the minimum local anesthetic volumes (MLAV) and doses (MLAD) of two concentrations of bupivacaine for epidural pain relief in labor, and to quantify the effect on dose. METHODS:Eighty women were randomized in a double-blind manner to receive a first bolus of ...

journal_title：Anesthesia and analgesia

authors： Lyons GR,Kocarev MG,Wilson RC,Columb MO

更新日期：2007-02-01 00:00:00

abstract：:Our goal in this study was to develop a robotic intubation system and to conduct a feasibility pilot study on the use of a robotic intubation system for endotracheal intubations. The Kepler Intubation System was developed, consisting of a remote control center (joystick and intubation cockpit) linked to a standard vid...

journal_title：Anesthesia and analgesia

authors： Hemmerling TM,Wehbe M,Zaouter C,Taddei R,Morse J

更新日期：2012-03-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：:The purpose of these experiments was to analyze the cerebrovascular and cerebral metabolic effects of midazolam, a short-acting water-soluble benzodiazepine, and to investigate its interaction with alcohol in rats. A benzodiazepine antagonist, 3-carbo-t-butoxy-beta-carboline (beta-CCT), was used to test the role of th...

journal_title：Anesthesia and analgesia

authors： Van Gorder PN,Hoffman WE,Baughman V,Albrecht RF,Miletich DJ,Guzman F,Cook JM

更新日期：1985-02-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：:Chronic, intermittent exposure to small amounts of ethanol reduces myocardial infarct size in vivo. We tested the hypothesis that acute administration of ethanol enhances the functional recovery of stunned myocardium and that adenosine triphosphate-dependent potassium (K(ATP)) channels mediate this beneficial effect. ...

journal_title：Anesthesia and analgesia

authors： Gross ER,Gare M,Toller WG,Kersten JR,Warltier DC,Pagel PS

更新日期：2001-02-01 00:00:00

abstract：:We studied the performance of a target-controlled drug infusion device, computer-assisted continuous infusion (CACI). Forty-one volunteers received one of midazolam (n = 11), propofol (n = 10), thiopental (n = 10), or fentanyl (n = 10) in sedative concentrations. Concentrations were kept constant for 45-70 min at five...

journal_title：Anesthesia and analgesia

authors： Veselis RA,Glass P,Dnistrian A,Reinsel R

更新日期：1997-05-01 00:00:00

abstract：UNLABELLED:We studied the ability of zonisamide (Zonegran) to relieve thermal hyperalgesia and/or mechanical allodynia in the chronic constriction injury model of neuropathic pain. Zonisamide (25, 50, or 100 mg/kg) or saline was administered in a blinded, randomized manner by intraperitoneal injection on postoperative ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Chalfoun AG,Azevedo MI

更新日期：2003-06-01 00:00:00

abstract：UNLABELLED:Despite clinical and laboratory evidence of perioperative hypercoagulability, there are no consistent data evaluating the extent, duration, and specific contribution of platelets and procoagulatory proteins by in vitro testing. We tested the hypothesis that the parallel use of standard and abciximab-cytochal...

journal_title：Anesthesia and analgesia

authors： Mahla E,Lang T,Vicenzi MN,Werkgartner G,Maier R,Probst C,Metzler H

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Pediatric chronic pain is very common and results in significant health care costs. Pediatric chronic pain is both an individual and a public health concern. The primary objective of this study was to generate a descriptive clinical profile of the patients referred to an anesthesiology-based pediatric chroni...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respi...

journal_title：Anesthesia and analgesia

authors： Nachman E,Clemensen P,Santos K,Cole AR,Polizzotti BD,Hofmann G,Leeman KT,van den Bosch SJ,Kheir JN

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:In children, the laryngeal mask airway (LMA) is frequently displaced within the hypopharynx, resulting in repositioning of the device. When the tip of the LMA is placed in the esophageal inlet, the arytenoids are moved ventrally. When the LMA is rotated or deviated, the ventral movement of the arytenoids may...

journal_title：Anesthesia and analgesia

authors： Kim J,Kim JY,Kim WO,Kil HK

更新日期：2015-02-01 00:00:00

abstract：:The understanding of anesthetic side effects on the heart has been hindered by the lack of sophisticated clinical models. Using micropatterned human-induced pluripotent stem cell-derived cardiomyocytes, we obtained cardiac muscle depressant profiles for propofol, etomidate, and our newly identified anesthetic compound...

journal_title：Anesthesia and analgesia

authors： Chang ACY,Chang ACH,Nicin L,Weber GJ,Holbrook C,Davies MF,Blau HM,Bertaccini EJ

更新日期：2020-01-01 00:00:00

abstract：UNLABELLED:Propofol is a cardiac depressant with minimal diastolic effects in the adult myocardium. Cardiac effects of propofol in the newborn are unknown. We examined hemodynamic variables and systolic and diastolic left ventricular function in 12 newborn pigs exposed to propofol at three different infusion rates (7.5...

journal_title：Anesthesia and analgesia

authors： Graham MR,Thiessen DB,Mutch WA

更新日期：1998-04-01 00:00:00

abstract：UNLABELLED:We evaluated the effect of 1, 20, and 40 mL of epidural saline flush on recovery from lidocaine epidural anesthesia. Eight volunteers were studied for three study periods, each separated by 72 h. The volume of saline was randomized, and a new catheter was inserted for each study period. A standardized dose o...

journal_title：Anesthesia and analgesia

authors： Chan VW,Nazarnia S,Kaszas Z,Perlas A

更新日期：1999-10-01 00:00:00

abstract：:This study reports plasma bupivacaine concentrations in 13 neonates who received lumbar epidural anesthesia during major abdominal surgery. A bolus of 1.8 mg/kg of bupivacaine (2.5 mg/mL) was administered after induction of anesthesia, followed by a continuous infusion of 0.2 mg.kg-1.h-1 (1.25 mg/mL). Plasma concentra...

journal_title：Anesthesia and analgesia

authors： Larsson BA,Lönnqvist PA,Olsson GL

更新日期：1997-03-01 00:00:00

abstract：:Ketamine has many neuromuscular effects in vitro. Its neuromuscular effects in vivo have been controversial and inconsistent. To systematically examine its neuromuscular effects over a wide dose range and its interaction with all popular nondepolarizing neuromuscular relaxants, the effects of ketamine 2, 5, and 10 mg/...

journal_title：Anesthesia and analgesia

authors： Tsai SK,Lee C

更新日期：1989-01-01 00:00:00

abstract：:Cardioprotection by anesthetic preconditioning (APC) can be abolished by nitric oxide (NO*) synthase inhibitors or by reactive oxygen species (ROS) scavengers. We previously reported attenuated mitochondrial electron transport (ET) and increased ROS generation during preconditioning sevoflurane exposure as part of the...

journal_title：Anesthesia and analgesia

authors： Riess ML,Kevin LG,McCormick J,Jiang MT,Rhodes SS,Stowe DF

更新日期：2005-01-01 00:00:00

abstract：:The potency of conventional inhaled anesthetics increases with increasing age: the 50% effective dose (minimum alveolar anesthetic concentration [MAC]) for anesthesia in the neonatal animal or human exceeds MAC in the young adult by approximately 30% to 60%. We tested whether this relationship also applies to the alka...

journal_title：Anesthesia and analgesia

authors： Fang Z,Gong D,Ionescu P,Laster MJ,Eger EI 2nd,Kendig J

更新日期：1997-04-01 00:00:00

abstract：:This retrospective case series of patients with refractory sacroiliac joint (SIJ) pain presents our first 77 SIJ radiofrequency ablation (RFA) procedures performed with a multilesion probe. Of these, 16 (20.8%) provided no relief; 55 (71.4%) provided >50% pain relief at 6 weeks; 42 (54.5%, 95% confidence interval, 42....

journal_title：Anesthesia and analgesia

authors： Schmidt PC,Pino CA,Vorenkamp KE

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：UNLABELLED:Pain complicates the recovery process after ambulatory surgery. We surveyed 175 ambulatory surgery patients to determine pain severity, analgesic use, relationship of pain to duration of recovery, and the relative importance of various factors to predicting these outcomes. Multivariate regression analysis wa...

journal_title：Anesthesia and analgesia

authors： Pavlin DJ,Chen C,Penaloza DA,Polissar NL,Buckley FP

更新日期：2002-09-01 00:00:00

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：IMPLICATIONS:A low-dose (4 mg), low-volume (0.8 mL), low-flow (2 min) technique with hyperbaric bupivacaine toward the dependent side oriented injection and maintenance of the lateral decubitus position for 10 min produced selective spinal anesthesia with rapid recession of motor block and early discharge home. ...

journal_title：Anesthesia and analgesia

authors： Valanne JV,Korhonen AM,Jokela RM,Ravaska P,Korttila KK

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Safe and effective alternatives are required in labor when epidural analgesia is not appropriate. We hypothesized that patient-controlled IV remifentanil labor analgesia would not be inferior to patient-controlled epidural labor analgesia. METHODS:This randomized nonblinded controlled noninferiority study i...

journal_title：Anesthesia and analgesia

authors： Stocki D,Matot I,Einav S,Eventov-Friedman S,Ginosar Y,Weiniger CF

更新日期：2014-03-01 00:00:00

abstract：:Forty neonates delivered by cesarean section were studied, half being delivered of mothers in whom anesthesia was induced with midazolam (0.3 mg/kg intravenously) and half of mothers given thiopental (4 mg/kg). At delivery, blood samples from mother and the umbilical vein were drawn for determination of plasma concent...

journal_title：Anesthesia and analgesia

authors： Bach V,Carl P,Ravlo O,Crawford ME,Jensen AG,Mikkelsen BO,Crevoisier C,Heizmann P,Fattinger K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Central venous cannulation is technically challenging in obese patients. We hypothesized that positive end-expiratory pressure (PEEP) increases the size of the internal jugular vein (IJV) in obese adults. METHODS:The circumference and cross-sectional area of the IJV were measured in obese patients under gen...

journal_title：Anesthesia and analgesia

authors： Downey LA,Blaine KP,Sliwa J,Macario A,Brock-Utne J

更新日期：2014-09-01 00:00:00

abstract：:Monitoring with pulse oximetry might improve patient outcome by enabling an early diagnosis and, consequently, correction of perioperative events that might otherwise cause postoperative complications or even death. The aim of the study was to clarify the effect of perioperative monitoring with pulse oximetry and to i...

journal_title：Anesthesia and analgesia

authors： Pedersen T,Møller AM,Pedersen BD

更新日期：2003-02-01 00:00:00