The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy.

abstract：:Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effect...

journal_title：Anesthesia and analgesia

authors： Grigore AM,Murray CF,Ramakrishna H,Djaiani G

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Tardiness from scheduled start times is a common source of frustration for both operating room (OR) personnel and patients. Factors that influence tardiness were quantified in a companion paper and have been used to develop interventions that have the potential for reducing tardiness. METHODS:Data from two ...

journal_title：Anesthesia and analgesia

authors： Wachtel RE,Dexter F

更新日期：2009-06-01 00:00:00

abstract：UNLABELLED:Recent investigations have sought to improve intrathecal analgesia by combining opioids with other classes of analgesics. In this study we assessed the ability of intrathecal midazolam to increase the potency and duration of the analgesic effects of intrathecal fentanyl without causing adverse effects. Thirt...

journal_title：Anesthesia and analgesia

authors： Tucker AP,Mezzatesta J,Nadeson R,Goodchild CS

更新日期：2004-06-01 00:00:00

abstract：:Combinations of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids are widespread in the management of pain, allowing better analgesia with reduced side effects. Cannabinoids are promising analgesic drugs that have pharmacological properties similar to those of opioids. However, the beneficial effects of cannabi...

journal_title：Anesthesia and analgesia

authors： Ulugöl A,Ozyigit F,Yesilyurt O,Dogrul A

更新日期：2006-02-01 00:00:00

abstract：UNLABELLED:Intrathecal (IT) sufentanil provides effective analgesia for extracorporeal shock wave lithotripsy. However, the optimal dose of sufentanil has not been established. We designed a prospective, randomized, double-blinded study to determine the optimal dose of IT sufentanil. Sixty men were randomized to receiv...

journal_title：Anesthesia and analgesia

authors： Lau WC,Green CR,Faerber GJ,Tait AR,Golembiewski JA

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Sepsis is currently the leading cause of direct maternal death in the United Kingdom. In this study, we aimed to determine frequency, temporal trends, and independent associations for severe sepsis during hospitalization for delivery in the United States. METHODS:Data were obtained from the Nationwide Inpat...

journal_title：Anesthesia and analgesia

authors： Bauer ME,Bateman BT,Bauer ST,Shanks AM,Mhyre JM

更新日期：2013-10-01 00:00:00

abstract：:We studied three groups of patients without previous renal impairment, undergoing elective coronary artery bypass surgery. Group H (n = 7) underwent open heart surgery using moderate hypothermia (28 degrees C); Groups N and M (n = 8, each) were managed at normothermia. The extracorporeal circuit was primed with Hartma...

journal_title：Anesthesia and analgesia

authors： Ip-Yam PC,Murphy S,Baines M,Fox MA,Desmond MJ,Innes PA

更新日期：1994-05-01 00:00:00

abstract：UNLABELLED:Nonsteroidal antiinflammatory drugs (NSAIDs) provide effective postoperative analgesia after arthroscopic knee surgery. Some investigators have suggested that the preemptive administration of NSAIDs may reduce postoperative analgesic requirements and hypersensitivity. We evaluated the analgesic effect of adm...

journal_title：Anesthesia and analgesia

authors： Reuben SS,Bhopatkar S,Maciolek H,Joshi W,Sklar J

更新日期：2002-01-01 00:00:00

abstract：:Intraocular pressure (IOP) measurements in children are usually performed under nitrous oxide and halothane anesthesia. We studied the effects of both time and end-tidal halothane concentration on IOP in 80 children (mean age +/- SD = 4.5 +/- 2.9 yr), to determine the most optimal time to make such measurements in ane...

journal_title：Anesthesia and analgesia

authors： Watcha MF,Chu FC,Stevens JL,Forestner JE

更新日期：1990-08-01 00:00:00

abstract：:The value of family-centered care in general and subspecialty pediatrics has been well documented in the literature. Translation of these principles into perioperative medicine has its logistical challenges; however, there are theoretical benefits. Specifically, pediatric patients with psychiatric diagnoses or special...

journal_title：Anesthesia and analgesia

authors： Ambardekar AP,Litman RS,Schwartz AJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have been linked to long-term potentiation, a process important in memory fo...

journal_title：Anesthesia and analgesia

authors： Zhang J,Sutachan JJ,Montoya-Gacharna J,Xu CF,Xu F,Neubert TA,Recio-Pinto E,Blanck TJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Anesthesia induction in children is frequently achieved by inhalation of nitrous oxide and sevoflurane. Pediatric anesthesiologists commonly use distraction techniques such as humor or nonprocedural talk to reduce anxiety and facilitate a smooth transition at this critical phase. There is a large body of suc...

journal_title：Anesthesia and analgesia

authors： Mifflin KA,Hackmann T,Chorney JM

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:Isoflurane reduces myocardial infarct size during early reperfusion by activating phosphatidylinositol-3-kinase (PI3K) signaling. We tested the hypothesis that this cardioprotection against reperfusion injury is enhanced by morphine and that a decrease in apoptosis plays a role in preservation of myocardial ...

journal_title：Anesthesia and analgesia

authors： Weihrauch D,Krolikowski JG,Bienengraeber M,Kersten JR,Warltier DC,Pagel PS

更新日期：2005-10-01 00:00:00

abstract：:Fifty-three swine from the University of Missouri Sinclair Medical Research Farm were used in experimentation to determine their susceptibility to malignant hyperthermia, to determine appropriate anesthetic agents for susceptible swine and to investigate appropriate pharmaceutical agents which could protect against th...

journal_title：Anesthesia and analgesia

authors： Short CE,Paddleford RR,McGrath CJ,Williams CH

更新日期：1976-09-01 00:00:00

abstract：UNLABELLED:The aim of the present study was to investigate the effect of somatostatin administration on experimentally induced inflammation in rats. Inflammation was induced by the intraplantar injection of carrageenan (50 microL) into the hind paw of the rat. Animals were treated intraplantarly with somatostatin in a ...

journal_title：Anesthesia and analgesia

authors： Corsi MM,Ticozzi C,Netti C,Fulgenzi A,Tiengo M,Gaja G,Guidobono F,Ferrero ME

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Pulmonary aspiration of gastric contents is associated with significant perioperative morbidity and mortality. Previous studies have investigated the validity, reliability, and possible clinical impact of gastric ultrasound for the assessment of gastric content at the bedside. In the present study, we examin...

journal_title：Anesthesia and analgesia

authors： Kruisselbrink R,Gharapetian A,Chaparro LE,Ami N,Richler D,Chan VWS,Perlas A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The diagnosis of myocardial infarction (MI) after noncardiac surgery has traditionally relied on using relatively insensitive contemporary cardiac troponin (cTn) assays. We hypothesized that using a recently introduced novel high-sensitivity cTnT (hscTnT) assay would increase the detection rate of perioperat...

journal_title：Anesthesia and analgesia

authors： Brown JC,Samaha E,Rao S,Helwani MA,Duma A,Brown F,Gage BF,Miller JP,Jaffe AS,Apple FS,Scott MG,Nagele P

更新日期：2017-11-01 00:00:00

abstract：:Selective segmental nerve blocks with local anesthetics are applied for diagnostic purposes in patients with chronic back pain to determine the segmental level of the pain. We performed this study to establish myotomal motor effects after L4 spinal nerve blocks by lidocaine and ropivacaine and to evaluate the relation...

journal_title：Anesthesia and analgesia

authors： Wolff AP,Wilder Smith OH,Crul BJ,van de Heijden MP,Groen GJ

更新日期：2004-08-01 00:00:00

abstract：:Despite the exhaustive search for an acceptable substitute to erythrocyte transfusion, neither chemical-based products such as perfluorocarbons nor hemoglobin-based oxygen carriers have succeeded in providing a reasonable alternative to allogeneic blood transfusion. However, there remain scenarios in which blood trans...

journal_title：Anesthesia and analgesia

authors： Jahr JS,Guinn NR,Lowery DR,Shore-Lesserson L,Shander A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Unicondylar knee arthroplasty (UKA) is a commonly performed procedure with significant expected postoperative pain. Peripheral nerve blocks are 1 analgesic option, but some approaches may decrease quadriceps motor strength and interfere with early ambulation. In this study, we compared the analgesia provided...

journal_title：Anesthesia and analgesia

authors： Henshaw DS,Jaffe JD,Reynolds JW,Dobson S,Russell GB,Weller RS

更新日期：2016-04-01 00:00:00

abstract：UNLABELLED:Thiamylal, a chiral thiobarbiturate, is marketed as a racemic product. We studied the serum protein binding and microsomal metabolism of thiamylal enantiomers in vitro. The unbound fraction of R(+)-thiamylal was greater than that of S(-)-thiamylal. The analysis of binding data revealed that both enantiomers ...

journal_title：Anesthesia and analgesia

authors： Sueyasu M,Fujito K,Shuto H,Mizokoshi T,Kataoka Y,Oishi R

更新日期：2000-09-01 00:00:00

abstract：:Leakge of lymph following puncture of the right subclavian vein occurred in a patient, requiring a pacemaker catheter. The lymph drainage settled spontaneously after 4 days on remanipulation of the pacing wire. ...

journal_title：Anesthesia and analgesia

authors： Ryan DW

更新日期：1978-01-01 00:00:00

abstract：:These experiments investigated the effect of halothane or fentanyl anesthesia on plasma atrial natriuretic polypeptide (ANP) and angiotensin II (AII) concentrations and the response to a 30% blood volume load in rats. Halothane (1.1% and 2.2% inspired) or fentanyl (50 and 200 micrograms/kg) anesthesia alone produced l...

journal_title：Anesthesia and analgesia

authors： Hoffman WE,Phillips MI,Kimura B

更新日期：1989-01-01 00:00:00

abstract：:Effects of halothane, enflurane, and nitrous oxide on ciliary beats were evaluated using a photoelectric system in dissected rabbit tracheal segments. Dose-dependent suppression of the frequency of ciliary beats of moderate degrees was observed after exposure of tracheal segments to warmed and humidified vapors of hal...

journal_title：Anesthesia and analgesia

authors： Lee KS,Park SS

更新日期：1980-06-01 00:00:00

abstract：:Although convective warming therapy is effective in preventing hypothermia in anesthetized patients, little is known concerning the potential risks of its use. Hence, this balanced cross-over study was designed to determine if the use of convective warming therapy increased the risk of wound contamination. For 4 h, ei...

journal_title：Anesthesia and analgesia

authors： Zink RS,Iaizzo PA

更新日期：1993-01-01 00:00:00

abstract：IMPLICATIONS:Misplacement of an epidural catheter into the subarachnoid space is a recognized complication. However, breakage of an intrathecal epidural catheter during removal presents a dilemma. Appropriate imaging, a neurosurgical consultation, and aggressive surgical exploration and extraction of the retained piece...

journal_title：Anesthesia and analgesia

authors： Ugboma S,Au-Truong X,Kranzler LI,Rifai SH,Joseph NJ,Salem MR

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventila...

journal_title：Anesthesia and analgesia

authors： Bachiller PR,McDonough JM,Feldman JM

更新日期：2008-05-01 00:00:00

abstract：:The charts of 1553 patients who were anesthetized for ambulatory surgery were analyzed retrospectively to determine the effect of the type of surgery, the age of the patient, the use of premedication, the duration of anesthesia, and the anesthetic technique on the duration of recovery and the rate of complications. In...

journal_title：Anesthesia and analgesia

authors： Meridy HW

更新日期：1982-11-01 00:00:00

abstract：UNLABELLED:Neuronal baseline K(+) channels were activated by several volatile anesthetics. Whole-cell recordings from cultured cerebellar granule neurons of 7-day-old male Sprague-Dawley rats showed outward-rectifying K(+) currents with a conductance of approximately 1.1 +/- 0.3 nS (n = 20) at positive potentials. The ...

journal_title：Anesthesia and analgesia

authors： Shin WJ,Winegar BD

更新日期：2003-05-01 00:00:00

abstract：:To compare the dose-response of remifentanil for tracheal intubation in infants and children, 32 healthy full-term infants and 32 children were anesthetized with 10 mug/kg glycopyrrolate and 4.0 mg/kg propofol and administered 1 of 4 doses of remifentanil (1.25, 1.50, 1.75, or 2.00 microg/kg) to facilitate tracheal in...

journal_title：Anesthesia and analgesia

authors： Crawford MW,Hayes J,Tan JM

更新日期：2005-06-01 00:00:00