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Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains.

Abstract：

:We have isolated cDNAs from normal human breast tissue and breast tumour cells that encode a protein (pez) with features of a novel non-receptor tyrosine phosphatase possessing N-terminal sequence homology to the ezrin-band 4.1-merlin-radixin protein family. Northern blot analysis indicates that pez is expressed in a variety of human tissues including kidney, skeletal muscle, lung and placenta. Fluorescence in situ hybridization has mapped pez to chromosome 1 region q32.2-41. Sequence identity to a characterized polymorphic marker confirms this localization.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Smith AL,Mitchell PJ,Shipley J,Gusterson BA,Rogers MV,Crompton MR

doi

10.1006/bbrc.1995.1591

subject

Has Abstract

pub_date

1995-04-26 00:00:00

pages

959-65

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(85)71591-4

journal_volume

209

pub_type

杂志文章

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