Protein sequence tags: a novel solution for comparative proteomics.

Abstract:

:Comparative proteome profiling using stable isotope peptide labelling and mass spectrometry has emerged as a promising strategy. Here, we show the broad potential of our proprietary protein sequence tag (PST) technology. A special feature of PST is its ability to detect a wide variety of proteins including the pharmaceutically relevant membrane and nuclear proteins. This procedure addresses a similar number of proteins, compared to the multidimensional protein identification technology approach, but offers additionally a quantitative analysis with its recently developed quantitative PST version.

journal_name

Proteomics

journal_title

Proteomics

authors

Kuhn K,Prinz T,Schäfer J,Baumann C,Schärfke M,Kienle S,Schwarz J,Steiner S,Hamon C

doi

10.1002/pmic.200401306

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

2364-8

issue

9

eissn

1615-9853

issn

1615-9861

journal_volume

5

pub_type

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