Abstract:
:An ultrasonic aerosol generator constructed from a domestic humidifier is described which has been used to produce liquid aerosols for physiological investigations. The instrument was constructed from a Pifco domestic humidifier modified to include an energy guide to direct the oscillations of the transducer through the coupling water, which would normally be aerosolized, onto a small membrane based sample chamber containing the liquid to be aerosolized. The size distribution of the aerosol produced was found to be between 2 and 6 mm, optimum for diffuse intrapulmonary deposition. Up to 4 ml/min of aqueous liquid was used; however the sample chamber could be made small enough to contain economic amounts of expensive material to administer by inhalation. The instrument has proved to be reliable over a period of three years.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Davies A,Hudson N,Pirie Ldoi
10.1016/1350-4533(95)97320-osubject
Has Abstractpub_date
1995-07-01 00:00:00pages
387-9issue
5eissn
1350-4533issn
1873-4030pii
1350-4533(95)97320-Ojournal_volume
17pub_type
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