Abstract：
:The paper described a limited part of the coagulation pathway, and in particular the inhibitory effects of activated protein C in the context of thrombin production. This is a computational modeling study with various assumption made of kinetic rates laws and their summation. The level of complexity and assumed parameters makes conclusions uncertain. However, an interesting outcome is that kinetic reaction rates may show oscillation behavior under particular, high levels of protein C feedback inhibition. The model would defy quantitative practical use, but could have predictive value as a qualitative descriptor of coagulation.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Qiao YH,Xu CQ,Zeng YJ,Xu XH,Zhao H,Xu Hdoi
10.1016/j.medengphy.2004.01.003subject
Has Abstractpub_date
2004-05-01 00:00:00pages
341-7issue
4eissn
1350-4533issn
1873-4030pii
S1350453304000050journal_volume
26pub_type
杂志文章abstract：:Zygomatic implant technology has been regarded as an alternative treatment to massive grafting surgery in the severe atrophic maxillary. Nowadays, the assistant method with a real-time surgical navigation has been applied to reduce the risks of zygomatic implant placement. However, the accuracy of the complex operatio...
journal_title：Medical engineering & physics
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更新日期：2020-01-01 00:00:00
abstract：:Tripolar systems have been implanted to reduce the risk of recurrent dislocation. However, there is little known about the dynamic behavior of tripolar hip endoprostheses under daily life conditions and achieved joint stability. Hence, the objective of this biomechanical study was to examine the in vivo dynamics and d...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.09.007
更新日期：2014-01-01 00:00:00
abstract：:Quantifying the risk of falling (falls risk) would be helpful in treating people with gait disorders. The gait sensitivity norm (GSN) is a stability measure that correlates well to risk of falling in passive dynamic walkers but has not been evaluated on humans or human-like walking models. We assessed the correlation ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.03.018
更新日期：2013-10-01 00:00:00
abstract：:Most surgical procedures in breast plastic surgery are either reconstructive procedures following oncologic interventions (tumorectomy, quadrantectomy, mastectomy ...) or aesthetic ones, both augmentation and reduction. With current techniques, the results of such procedures cannot be fully guaranteed. Usually, surgic...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2008.01.005
更新日期：2008-11-01 00:00:00
abstract：:Medical imaging and clinical studies have proven that the heart pumps by means of minor outer volume changes and back-and-forth longitudinal movements in the atrioventricular (AV) region. The magnitude of AV-plane displacement has also shown to be a reliable index for diagnosis of heart failure. Despite this, AV-plane...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.11.002
更新日期：2015-01-01 00:00:00
abstract：:This paper reports on the findings of an extensive survey investigating practising design engineers' perceptions of new product development within the UK medical device industry. The design activity recorded was predominantly the small-scale development of low volume products. Explicit formal procedures were rarely us...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(96)00021-5
更新日期：1996-12-01 00:00:00
abstract：:This proof-of-concept study designs distal femur fracture plates from semi-rigid materials vs. traditional metals for toe-touch weight-bearing recommended to patients immediately after surgery. The two-fold goal was to (a) reduce stress shielding (SS) by increasing cortical bone stress thereby reducing the risk of bon...
journal_title：Medical engineering & physics
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doi：10.1016/j.medengphy.2020.11.015
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abstract：:The Fit4Purpose project aims to develop upper limb prosthetic devices which are suitable for deployment in lower- and middle-income countries (LMIC's). Open-frame trans-radial socket designs are being considered, formed of several, linked components, including pads which interface directly with the skin surface. A mec...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.08.003
更新日期：2020-10-01 00:00:00
abstract：:During fatiguing contractions, many adjustments in motor units behaviour occur: decrease in muscle fibre conduction velocity; increase in motor units synchronisation; modulation of motor units firing rate; increase in variability of motor units inter-spike interval. We simulated the influence of all these adjustments ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2016.09.022
更新日期：2016-12-01 00:00:00
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journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(94)90014-0
更新日期：1994-01-01 00:00:00
abstract：:Two optimization-driven approaches were employed to develop kinematics-driven (KD) and stability-based kinematics-driven (SKD) musculoskeletal models of an adult thoracolumbar to ascertain the significance of spine stability in holding the upright-standing posture after muscular disuse atrophy. Both models were used t...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2019.07.008
更新日期：2019-11-01 00:00:00
abstract：:A major challenge during minimally invasive surgery is transfer of high forces through small, flexible instruments, such as needles and catheters, because of their low buckling resistance. In this study, we determined the feasibility of using a Newton's Cradle-inspired catheter (patented) to transfer high-force impuls...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2018.12.025
更新日期：2019-05-01 00:00:00
abstract：:Currently, the study of ion composition and performance in human biofluids plays an important role in biomedical engineering research and technology. This field may become universal for human diagnostics; it allows early detection of different diseases in humans by measuring changes in ion behaviour in human biofluids...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2011.04.007
更新日期：2011-11-01 00:00:00
abstract：:The construction and performance of a 5.4 m3 combined direct and indirect calorimeter for human subjects is described. The calorimeter was constructed for studies on human subjects primarily undergoing fast alterations in heat production and heat losses, e.g. after a meal or during physical exercise. A heat sink and a...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(98)00037-x
更新日期：1998-06-01 00:00:00
abstract：:The concept of a monolithic Ti-Ni spinal rod with variable flexural stiffness is proposed to reduce the risks associated with spinal fusion. The variable stiffness is conferred to the rod using the Joule-heating local annealing technique. The annealing temperature and the mechanical properties' distributions resulted ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.07.012
更新日期：2014-11-01 00:00:00
abstract：:In the fields of medicine and biomechanics, MEMS accelerometers are increasingly used to perform activity recognition by directly measuring acceleration; to calculate speed and position by numerical integration of the signal; or to estimate the orientation of body parts in combination with gyroscopes. For some of thes...
journal_title：Medical engineering & physics
pub_type： 杂志文章,评审
doi：10.1016/j.medengphy.2016.08.004
更新日期：2016-11-01 00:00:00
abstract：:Fitts' Law was extended in the polar coordinate system, and a set of indices for human motion evaluation is proposed. In this paper, the index of difficulty and the index of performance are introduced as the general indices for the quality measure of plane target-to-target movement. As an example, the target-reaching ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(01)00121-7
更新日期：2002-03-01 00:00:00
abstract：:The rehabilitation engineering community is working towards the development of robotic devices that can assist during gait training of patients suffering from neurologic injuries such as stroke and spinal cord injuries (SCI). The field of robot assisted treadmill training has rapidly evolved during the last decade. Th...
journal_title：Medical engineering & physics
pub_type： 杂志文章,评审
doi：10.1016/j.medengphy.2010.12.010
更新日期：2011-06-01 00:00:00
abstract：:Electromyography (EMG) has been widely used for the assessment of musculoskeletal functions and the control of electrical prostheses, which make use of the EMG signal generated by the contraction of the residual muscles. In spite of the successful applications of EMG in different fields, it has some inherent limitatio...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2005.07.012
更新日期：2006-06-01 00:00:00
abstract：:In this study, we propose a new classification method for early differentiation of paroxysmal and persistent atrial fibrillation episodes, i.e. those which spontaneously or with external intervention will return to sinus rhythm within 7 days of onset from the ones where the arrhythmia is sustained for more than 7 days...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2016.10.013
更新日期：2017-01-01 00:00:00
abstract：AIMS:This study investigated the feasibility of automated differentiation between essential tissue types encountered during laparoscopic colorectal surgery using spectral analysis. METHODS:Wide band (440-1830 nm) spectra were collected using an optical fiber probe and spectrometer from freshly explanted, ex vivo, huma...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.01.004
更新日期：2013-07-01 00:00:00
abstract：:The purpose of this study is to demonstrate a new MRI compatible loading device capable of reconstructing realistic loading scenarios of the human foot for research in the field of foot biomechanics. This device has two different configurations: one used to compress the forefoot and one to bend the metatarsophalangeal...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.06.006
更新日期：2014-09-01 00:00:00
abstract：:Despite our understanding of the importance of falling, previous studies have ignored the effects of falls from standing height. In this article, lumped parameter linear and nonlinear models of a standing human have been used to simulate the impact response of the body segments due to inputs at the shoes. The accelera...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(96)00081-1
更新日期：1997-06-01 00:00:00
abstract：:The standard camera- and force plate-based set-up for motion analysis suffers from the disadvantage of being limited to laboratory settings. Since adaptive algorithms are able to learn the connection between known inputs and outputs and generalise this knowledge to unknown data, these algorithms can be used to leverag...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.10.001
更新日期：2020-12-01 00:00:00
abstract：:Accurate three-dimensional tumor localisation in Radiotherapy, is critical to the treatment outcome, particularly when high dose gradients are present. A number of techniques have been proposed for the localisation of anatomical structures or markers. The present study proposes an approach to a concurrent maximisation...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(99)00015-6
更新日期：1999-03-01 00:00:00
abstract：:The acoustic power of high-intensity focused ultrasound (HIFU) is an important parameter that should be measured prior to each treatment to guarantee effective and safe outcomes. A new calibration technique was developed that involves estimating the pressure distribution, calculating the acoustic power using an underw...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2015.01.014
更新日期：2015-03-01 00:00:00
abstract：:Although the precise causes of Sudden Infant Death Syndrome (SIDS) are still unclear there is evidence to suggest that hypoxaemia may be a contributory factor. Transcutaneous oxygen monitors can be used but are unsatisfactory for young babies in the home. As an alternative approach, respiratory patterns can be studied...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(94)90005-1
更新日期：1994-01-01 00:00:00
abstract：:The aim of this study is to develop a technical quality evaluation system of electroencephalogram (EEG) recording in order to acquire technically satisfactory EEG records, which may contribute to the accuracy improvement of EEG interpretation. In our developed system, the evaluation of EEG recording comprises the dete...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2004.09.001
更新日期：2005-01-01 00:00:00
abstract：:The second-order difference plot, as a modified Poincaré plot, is one of the important approaches for assessing the dynamics of heart rate variability. However, corresponding quantitative analysis methods are relatively limited. Based on the second-order difference plot, we propose a novel method, called the multi-sca...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.09.015
更新日期：2014-12-01 00:00:00
abstract：:Musculoskeletal simulations are an essential tool for studying functional implications of pathologies and of potential surgical outcomes, e.g., for the complex shoulder anatomy. Most shoulder models rely on line-segment approximation of muscles with potential limitations. Comprehensive shoulder models based on continu...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.04.010
更新日期：2020-08-01 00:00:00
