Abstract：
OBJECTIVE:To test the hypothesis that cardiovascular reactivity to laboratory mental stressors interacts with job strain in predicting blood pressure at work. DESIGN:Ambulatory monitoring of blood pressure and heart rate was carried out for an 8-h period on a work day and on an equivalent non-work day in 49 male firefighters. METHODS:Participants were recruited from a larger cohort (n = 90) on the basis of showing high or low systolic reactions to mental arithmetic 15-24 months previously, coupled with high or low ratings of perceived job strain (high demand-low control). Four groups were tested: low job strain-low systolic reactors (n = 12), low job strain-high systolic reactors (n = 12), high job strain-low systolic reactors (n = 12) and high job strain-high systolic reactors (n = 13). RESULTS:Systolic blood pressure (SBP) was higher on work than non-work days, and diastolic blood pressure and heart rate were higher at work in the morning but not in the afternoon. These effects were due partly to posture and physical activity differences between the two days. Neither job strain nor laboratory reactivity independently predicted ambulatory blood pressure. However, SBP was significantly higher during the afternoon at work in the high job strain-high systolic reactors than in the other groups. This was independent of baseline SBP, and was not due to differences in posture or activity at the time of recordings. Ambulatory SBP reactivity (difference between ambulatory values and workplace resting levels) in the afternoon at work was also elevated significantly in high job strain-high systolic reactors compared with in the other groups. CONCLUSIONS:The results support the hypothesis that individual differences in the appraisal of work stress modulate the relationship between stress reactivity and ambulatory blood pressure.
journal_name
J Hypertensjournal_title
Journal of hypertensionauthors
Steptoe A,Roy MP,Evans O,Snashall Dsubject
Has Abstractpub_date
1995-02-01 00:00:00pages
201-10issue
2eissn
0263-6352issn
1473-5598journal_volume
13pub_type
杂志文章abstract：BACKGROUND:The screening for primary aldosteronism is based on the aldosterone-renin ratio calculated with the plasma renin activity (PRA) value as denominator. A direct measurement of active renin (DRA) is being used as an alternative to PRA, but its diagnostic performance remains unclear. METHOD:We, therefore compar...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0b013e32833d2192
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis in the two-kidney, o...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000000370
更新日期：2015-01-01 00:00:00
abstract：:Haemorheological characteristics were measured in a group of 52 patients with essential arterial hypertension (HT), and were compared with those of a group of normotensive subjects. The relationships between the arterial blood pressure (BP), the echocardiographic indices of left ventricular hypertrophy (LVH), and the ...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVES:To investigate whether glucose or insulin is the cause of increases in oxidative stress and blood pressure in insulin-resistant animals, and to evaluate the effects of alpha-lipoic acid (LA) on the production of the superoxide anion (O2-) in the aorta and blood pressure elevations in various models of diabet...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/01.hjh.0000160215.78973.ba
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:To examine the changes in plasma brain natriuretic peptide (BNP), atrial natriuretic peptide (ANP) and blood pressure in patients with essential hypertension on a low, normal and high sodium intake. DESIGN AND METHODS:Twelve patients with mild-to-moderate essential hypertension were studied. Plasma, urinary ...
journal_title：Journal of hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To assess cardiac function, myocardial mechanoenergetic efficiency (MEE), and ventricular-arterial coupling (VAC) longitudinally during normal pregnancy, and to study if there was an association between cardiac structure and function, and fetal growth. METHODS:Cardiac structure and function, MEE, and ventric...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000001612
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:Development of internally quenched fluorogenic substrates for sensitive and continuous assays of angiotensin I-converting enzyme (ACE). DESIGN:We synthesized internally quenched fluorogenic bradykinin-related peptides introducing Abz (ortho-aminobenzoic acid) and EDDnp (N-[2,4-dinitrophenyl]-ethylenediamine)...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/00004872-199917050-00010
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVES:Retinal blood vessels may develop vasculopathy and apoptosis in response to hypertension. The present study was aimed at testing the role of losartan, a specific antagonist of angiotensin II receptor type 1 receptor in regulation of vascular apoptosis in retinal vasculature with hypertension. METHODS:Losart...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0b013e328333663f
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE(S):To study the changes in macrophage inducible nitric oxide synthase (iNOS) activity, plasma levels of nitrite, lipid peroxidation (LPO) and melatonin in human essential hypertension before and 6 months after 4 mg/day lacidipine treatment. DESIGN:The study was carried out in a total of 25 subjects--11 healt...
journal_title：Journal of hypertension
pub_type： 临床试验,杂志文章
doi：10.1097/00004872-200403000-00027
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:Immigration studies can shed light on hypertension development and reveal high-risk populations. To this end, we investigated the association between age at immigration and hypertension occurrence at adolescence among immigrants to Israel. METHODS:We analyzed cross-sectional data on 2 681 294 adolescents as...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000001957
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:Obstructive sleep apnoea (OSA) and hypertension frequently coexist, and both are associated with higher night-time than daytime urine sodium excretion rate (UNaV). However, the relative contribution of each condition is unknown. We compared the circadian pattern of UNaV in hypertensive and normotensive patie...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000000327
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To identify predictors of pregnancy-induced hypertension and pre-eclampsia in 212 nulliparous women before 20 weeks' gestation and at approximately 28 weeks' gestation. STUDY DESIGN:A randomized, prospective study in a teaching hospital. We performed standardized measurements of systolic and diastolic arteri...
journal_title：Journal of hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00004872-199816020-00013
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:Functional sex differences are described in several vascular beds. In the case of renal vessels, sex differences could influence processes like regulation of blood pressure and ion balance. Angiotensin II and nitric oxide are important regulators of renal vascular tone. Females have higher nitric oxide syntha...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0b013e32835731dd
更新日期：2012-09-01 00:00:00
abstract：:: The hypertension paradigm has contributed to a dramatic reduction in CVD mortality. This has been achieved by applying average results of population studies to identify a target population and design a common intervention to achieve a BP goal. Progressive lowering of the BP threshold has expanded the fraction of per...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000002375
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:Reduction in capillary density or rarefaction is a hallmark of essential hypertension. We measured the retinal capillary density using noninvasive optical coherence tomographic angiography (OCT-A) in adults with treated systemic hypertension and determined possible correlations with ambulatory blood pressure ...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000001916
更新日期：2019-03-01 00:00:00
abstract：AIM:To examine the effect of renal denervation (RDN) on blood pressure (BP) and health-related quality of life (QoL) in patients with resistant hypertension, pseudoresistant hypertension due to a white-coat effect and in patients with uncontrolled masked hypertension. METHODS:Using the Medical Outcomes Study 36-Item S...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000000698
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:The purpose of this study was to examine pressor responsiveness in a rabbit model with adrenal perturbation. Adrenals in rabbits were stabbed with a needle, and the rabbits were given water (adrenal-water group) or 0.9% NaCl (adrenal-salt) to drink; additional rabbits were sham-operated and given water (sham-water gro...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/00004872-198502000-00014
更新日期：1985-02-01 00:00:00
abstract：BACKGROUND:Left ventricular (LV) remodeling and aortic stiffness have independent predictive value for all causes and cardiovascular mortality. Because elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that local and regional aortic stiffness could differently impact on LV remodelin...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000001597
更新日期：2018-03-01 00:00:00
abstract：:Exogenous sex hormone use, including oral contraceptives, post-menopausal hormonal therapy and anabolic steroids, has been associated with blood pressure changes in both sexes, but little is known about the relationship between blood pressure and endogenous sex hormones. We examined this relationship in men in the Ran...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVE:To investigate the role of the renal medulla in early hypertension in spontaneously hypertensive rats (SHR), and to explore whether the attenuated increase of pressure induced by enalapril treatment is affected by chemical medullectomy. DESIGN:Forty-four male SHR were studied from 5 to 18 weeks of age: 22 re...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/00004872-199211000-00006
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVE:This study was designed to evaluate the capacity of norepinephrine (NE) to induce hypertrophic remodeling of small arteries in rats, and to determine the involvement of endothelin (ET) to initiate and maintain it. DESIGN AND RESULTS:Treatment with NE (2.5 microg/kg per min) for 14 or 28 days produced a simil...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/00004872-200110000-00014
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the wave reflection characteristics in the aortic arch and common carotid artery of ex-preterm adolescents and assess their relationship to central blood pressure in a cohort followed prospectively since birth. METHODS:Central blood pressures, pulse wave velocity, augmentation index, microvascula...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000001719
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:To investigate the influence of angiotensin II (All) receptors in isolated hepatic nuclei on other genes regulated by All and to determine whether the function of these intracellular receptors is influenced by alterations in the endocrine renin system. METHODS:Nuclei were isolated from hepatic tissue of nor...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：CONTEXT:There is a growing prevalence of cardiovascular disease (CVD) risk factors in West Africa and among its migrants to industrialized countries. Despite this, no study has reviewed CVD risk factor prevalence among West Africans in Africa and industrialized countries. OBJECTIVE:To appraise studies on the prevalenc...
journal_title：Journal of hypertension
pub_type： 杂志文章,评审
doi：10.1097/HJH.0000000000000061
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:To assess the influence of sodium intake on the two components of arterial blood pressure [mean blood pressure (MBP) and pulse pressure] and left ventricular mass (LVM) in normotensive subjects and never-treated hypertensive patients. METHODS:Blood pressure, LVM (M-mode echocardiography) and sodium excretio...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/00004872-200404000-00011
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVES:In experimental animal models, exogenous aldosterone excess has been linked to the progression of renal disease. However, the evidence of an increased risk of renal damage in patients affected by primary aldosteronism remains controversial. We aimed at evaluating the association between primary aldosteronism...
journal_title：Journal of hypertension
pub_type： 杂志文章,meta分析
doi：10.1097/HJH.0000000000002216
更新日期：2020-01-01 00:00:00
abstract：:Diabetic nephropathy has developed into a worldwide epidemic and is responsible for the majority of end-stage renal disease in most countries. Antihypertensive treatment slows the progression of the disease. In addition, blockade of the renin-angiotensin system reduces the degree of albuminuria and angiotensin II rece...
journal_title：Journal of hypertension
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/01.hjh.0000202820.56201.e6
更新日期：2006-02-01 00:00:00
abstract：:Conscious male beagle dogs were given constant intravenous infusions of noradrenaline for 14 days, four receiving 125 ng/kg/min and four 250 ng/kg/min. Before, during and after these infusions dose-response studies were done in which additional noradrenaline was infused at 500, 1000 and 2000 ng/kg/min, each rate for 1...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：
更新日期：1983-06-01 00:00:00
abstract：BACKGROUND:Increased arterial stiffness is associated with cardiovascular morbidity and mortality among hypertensive patients. OBJECTIVES:To assess the relationship between ambulatory arterial stiffness index (AASI) and subclinical left ventricular (LV) systolic dysfunction assessed by 2-D speckle-tracking echocardiog...
journal_title：Journal of hypertension
pub_type： 杂志文章
doi：10.1097/HJH.0000000000002330
更新日期：2020-05-01 00:00:00
