Abstract:
:This study examines childhood cancer risk in relation to certain factors likely to indicate magnetic field exposure from ground currents in the home. Substantial ground currents are most often found in homes having conductive plumbing, in which an uninterrupted metallic path in the water pipes and water main connects the grounding systems of neighboring houses. Information on plumbing conductivity was obtained from water suppliers for the homes of 347 cases and 277 controls identified in an earlier study of magnetic field exposure and childhood cancer in the Denver area. An increased cancer risk was observed for children in homes with conductive plumbing: The matched odds ratio was 1.72 (1.03-2.88) and increased to 3.00 (1.33-6.76) when analysis was limited to cases and controls who were residentially stable from the reference date to the study date. A measurement metric likely to indicate active ground currents (measurements having above-median intensity and a nonvertical orientation of < 55 degrees from the horizontal) was identified. In contrast to measured field intensity alone, for which only modest associations with cancer have been reported, this metric shows a high and significant cancer risk [matched O.R. = 4.0 (1.6-10.0)] consistent over a range of intensity and angle cutpoints. Such elevated nonvertical fields were also associated with cancer in an independent data set, which was gathered to study adult nonlymphocytic leukemia in the Seattle area. The associations of cancer with conductive plumbing and with this exposure metric both suggest that cancer risk is increased among persons with elevated magnetic field exposure from residential ground currents.
journal_name
Bioelectromagneticsjournal_title
Bioelectromagneticsauthors
Wertheimer N,Savitz DA,Leeper Edoi
10.1002/bem.2250160204subject
Has Abstractpub_date
1995-01-01 00:00:00pages
86-96issue
2eissn
0197-8462issn
1521-186Xjournal_volume
16pub_type
杂志文章abstract::We developed a new computer wire coding method and then applied it to investigate the suggestion that control selection bias might explain the observed association between wire codes and childhood cancer made in the study conducted by Savitz et al. in the Denver area. The computer wire coding method used a geographic ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::To evaluate duration- and dose-dependent effects of continuous exposure to a 60 Hz magnetic field (MF) on the testes in mice, BALB/c male mice were exposed to a 60 Hz MF at 100 μT for 24 h a day for 2, 4, 6, or 8 weeks, and at 2, 20, or 200 μT for 24 h a day for 8 weeks. Any exposures to MF did not significantly affec...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21819
更新日期:2014-02-01 00:00:00
abstract::Both positive and negative biological effects of microwaves on drug actions in rats exposed to 1-mW/cm2, 2,450-MHz microwaves have been reported by several investigators. We conducted dosimetry studies for seven different exposure conditions to determine whether these different results could be due to the rats having ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250060108
更新日期:1985-01-01 00:00:00
abstract::Effects of magnetic fields (MFs) on the activities of antioxidant enzymes of suspension-cultured tobacco cells were investigated. Compared with the control cells, exposure of the cells to static MF with the magnitudes of 10 and 30 mT for 5 days, 5 h each day, increased the activity of superoxide dismutase (SOD). In co...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20262
更新日期:2007-01-01 00:00:00
abstract::Magnetotactic bacteria produce nanometer-size intracellular magnetic crystals. The superior crystalline and magnetic properties of magnetosomes have been attracting much interest in medical applications. To investigate effects of intense static magnetic field on magnetosome formation in Magnetospirillum magneticum AMB...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20469
更新日期:2009-05-01 00:00:00
abstract::We study the effect of microwaves at 2,450 MHz on protein unfolding using surface plasmon resonance sensing. Our experimental method makes use of the fact that unfolding proteins tend to bind to chaperones on their unfolding pathway and this attachment is readily monitored by surface plasmon resonance. We use the prot...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20382
更新日期:2008-05-01 00:00:00
abstract::This paper traces the history of the development of the Radiofrequency Radiation Dosimetry Handbook and its subsequent impact on radio frequency radiation exposure standards. The author's recollections are used to illustrate the behind the scenes efforts of the individuals involved in this project. The development of ...
journal_title:Bioelectromagnetics
pub_type: 历史文章,杂志文章
doi:10.1002/(sici)1521-186x(1999)20:4+<9::aid-bem3>3.3
更新日期:1999-01-01 00:00:00
abstract::The effects of millimeter microwaves in the frequency range of 54-76 GHz on capacitance and conductance of lipid bilayer membranes (BLM) were studied. Some of the membranes were modified by gramicidin A and amphotericin B or by tetraphenylboron anions (TPhB-). The millimeter microwaves were pulse-modulated (PW) at rep...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160209
更新日期:1995-01-01 00:00:00
abstract::The constant exposure of modern society to extremely low frequency magnetic fields (ELF-MF) has raised considerable concerns about the potential risks to male reproduction. However, the epidemiological and experimental data remain contradictory and inconclusive. In the present study, we investigated the effects of 50 ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21816
更新日期:2014-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20477
更新日期:2009-05-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1997)18:4<299::aid-bem2>3.
更新日期:1997-01-01 00:00:00
abstract::This report describes some experimental measurements of the internal field levels induced within isolated chick-forebrains irradiated at 50, 147, and 450 MHz, under essentially the same conditions as those used in the in vitro calcium-ion efflux experiments. Ratios of incident power at 50/147 MHz and 147/450 MHz that ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250050302
更新日期:1984-01-01 00:00:00
abstract::Drosophila larvae reared inside a micro-metal box with an internal field strength 0.004 microT, were treated with a magnetic field of 50 Hz, 8 microT. for 20 min. Control experienced 0.004 microT. Cellular transcript levels were assessed using slot blots and quantified using a Phosphorimager. Blots were hybridised usi...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::To characterize the inhibitory effect of a static magnetic field, action potentials (AP) were elicited by intracellular application of 1 ms depolarizing current pulses of constant amplitude to the somata of adult mouse dorsal root ganglion neurons in monolayer dissociated cell culture. During the control period, < 5% ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250160108
更新日期:1995-01-01 00:00:00
abstract::The objective of this study was to develop a model for testing various hypotheses concerning possible mechanisms whereby electromagnetic fields might induce suppression of nighttime melatonin production in rodents. A published method for digesting freshly obtained pineal glands to the single cell level was modified, y...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The objective was to study the risk of cytogenetic damage among high voltage laboratory workers exposed to electromagnetic fields and mineral oil. This is a cross sectional study of 24 exposed and 24 matched controls in a Norwegian transformer factory. The exposure group included employees in the high voltage laborato...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.33
更新日期:2001-04-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20412
更新日期:2008-09-01 00:00:00
abstract::We describe devices designed for magnetic field exposures in which field amplitude and gradients are controlled simultaneously. Dosimetry based on field continuation of high resolution magnetic field scans and numerical models is compared with validation measurements. The dosimetry variables we consider are based on t...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20098
更新日期:2005-05-01 00:00:00
abstract::In epidemiological studies of electromagnetic fields and health effects, exposure classification is crucial. There is no generally accepted biophysical interaction mechanism, but many studies are based on the hypothesis of a causal relationship with the strength of magnetic field. Some definition of the magnitude of e...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(SICI)1521-186X(1996)17:3<209::AID-BEM6>3.
更新日期:1996-01-01 00:00:00
abstract::The dielectric properties of the bovine brain grey and white matter in the frequency range from 20 kHz to 100 MHz were measured at different times following animal death. Changes in the dielectric parameters versus time are interpreted in terms of the reduction of the cell volume fraction that results from either cell...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250070105
更新日期:1986-01-01 00:00:00
abstract::Magnetic resonance (MR)-based electrical impedance tomography (MREIT) is a widely used imaging technique that provides high-resolution conductivity images at DC or below the 1 kHz frequency range. Using an MR scanner, this technique injects imaging currents into the human body and measures induced internal magnetic fl...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.21852
更新日期:2014-07-01 00:00:00
abstract::We have exposed cultured bone cells to a pulsed electromagnetic field (PEMF) for different times to find the minimal exposure time necessary to stimulate an increase of DNA synthesis. We used two different human osteosarcoma cell lines, TE-85 and MG-63, and human normal osteoblast cell (NHOC) obtained from surgical bo...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/(sici)1521-186x(1999)20:3<177::aid-bem4>3.
更新日期:1999-01-01 00:00:00
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journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.66
更新日期:2001-09-01 00:00:00
abstract::We present a simple readout device that fills the void produced by the gradual disappearance of the Vitck model 101 Electrothermia Monitor. The new device uses commercially available probes that are similar to Bowman's (IEEE Trans Microwave Theory Tech MTT-24:43-45, 1976) original design. As described, the device cove...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.2250100210
更新日期:1989-01-01 00:00:00
abstract::In this study, we measured and analyzed the spectral characteristics of a low-frequency magnetic field (MF) inside several gasoline-powered cars while driving on busy city roads. The spectra obtained upon measurements in the interior of the cars are compared with those measured in office locations at different times o...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22269
更新日期:2020-07-01 00:00:00
abstract::This study deals with the morphofunctional influence of 72 h exposure to a 6 mT static magnetic field (SMF) during differentiation induced by 50 ng/ml 12-O-tetradecanoyl-13-phorbol acetate (TPA) in human leukaemia U937 cells. The cell morphology of U937 cells was investigated by optic and electron microscopy. Specific...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20474
更新日期:2009-07-01 00:00:00
abstract::Laboratory measurements of electric fields have been carried out around examples of smart meter devices used in Great Britain. The aim was to quantify exposure of people to radiofrequency signals emitted from smart meter devices operating at 2.4 GHz, and then to compare this with international (ICNIRP) health-related ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.22044
更新日期:2017-05-01 00:00:00
abstract::Sixteen pregnant Holstein heifers weighing 521 +/- 46 kg, at 3.3 +/- 0.7 months of gestation and 2.2 +/- 2.0 months of age were confined to wooden metabolism cages and were exposed to a vertical electric field (EF) of 10.0 +/- 0.4 kV/m and an artificial light cycle of 12 h light-12 h dark. The heifers were divided int...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20020
更新日期:2004-05-01 00:00:00
abstract::The controversy over the possible association between magnetic field exposure and childhood leukemia has led several researchers to summarize the literature using meta-analysis. This paper reviews these previous meta-analyses and extends them by adding results from four studies published since the most recent analysis...
journal_title:Bioelectromagnetics
pub_type: 杂志文章,meta分析
doi:10.1002/1521-186x(2001)22:5+<::aid-bem1026>3.3.co;
更新日期:2001-01-01 00:00:00
abstract::Human glioma MO54 cells were used to investigate whether radio frequency (RF) field exposure could activate stress response genes. Cells were exposed to continuous wave 1950 MHz or sham conditions for up to 2 h. Specific absorption rates (SARs) were 1, 2, and 10 W/kg. For the cell growth experiment, cell numbers were ...
journal_title:Bioelectromagnetics
pub_type: 杂志文章
doi:10.1002/bem.20077
更新日期:2005-05-01 00:00:00