Abstract:
:The authors studied presymptomatic individuals with the Huntington disease (HD) mutation to determine whether cortical thinning was present. They found thinning that was regionally selective, semi-independent of striatal volume loss, and correlated with cognitive performance. Early, extensive cortical involvement occurs during the preclinical stages of HD.
journal_name
Neurologyjournal_title
Neurologyauthors
Rosas HD,Hevelone ND,Zaleta AK,Greve DN,Salat DH,Fischl Bdoi
10.1212/01.wnl.0000174432.87383.87subject
Has Abstractpub_date
2005-09-13 00:00:00pages
745-7issue
5eissn
0028-3878issn
1526-632Xpii
65/5/745journal_volume
65pub_type
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