Abstract:
:Functional decline for each decade at symptom onset and need for cane, walker, or wheelchair were assessed in 78 biopsy-proved patients with sporadic inclusion body myositis. Patients with disease onset between 40 and 59 years used a walker after 10.2 +/- 5.8 years, whereas those with disease onset between 60 and 79 years used a walker after 5.7 +/- 5.0 years (p = 0.05). Because patients progress faster to disability when symptoms begin after the age of 60, age at disease onset may define patient subsets for stratification in clinical trials.
journal_name
Neurologyjournal_title
Neurologyauthors
Peng A,Koffman BM,Malley JD,Dalakas MCdoi
10.1212/wnl.55.2.296subject
Has Abstractpub_date
2000-07-25 00:00:00pages
296-8issue
2eissn
0028-3878issn
1526-632Xjournal_volume
55pub_type
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