Abstract:
:Several recent papers show that differences in histone modification and the use of histone variants at the 5' and 3' ends of genes influence the location and kinetics of transcriptional initiation. The ultimate target of most epigenetic mechanisms may be the regulation of nucleosome occupancy, which in turn controls access to DNA at specific genomic locations.
journal_name
Celljournal_title
Cellauthors
Lieb JD,Clarke NDdoi
10.1016/j.cell.2005.12.010subject
Has Abstractpub_date
2005-12-29 00:00:00pages
1187-90issue
7eissn
0092-8674issn
1097-4172pii
S0092-8674(05)01392-9journal_volume
123pub_type
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