Abstract:
:Cells are protected from endoplasmic reticulum stress through the unfolded protein response (UPR). In this issue of Cell, Schinzel, Higuchi-Sanabria, Shalem et al., identify a mechanism that helps cells cope with ER stress but is independent of canonical UPR activation, instead involving the extracellular matrix hyaluronidase, TMEM2, as a signaling mediator.
journal_name
Celljournal_title
Cellauthors
Koopman M,Hetz C,Nollen EAAdoi
10.1016/j.cell.2019.11.012subject
Has Abstractpub_date
2019-11-27 00:00:00pages
1246-1248issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(19)31268-1journal_volume
179pub_type
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