Ulcerative colitis responsive to smoking and to nicotine chewing gum in a patient with alpha 1 anti-trypsin deficiency.

Abstract:

:Ulcerative colitis is one of the few diseases in which smoking appears to confer some benefit (1). We report a patient whose ulcerative colitis deteriorated on several occasions on stopping cigarettes, and improved on restarting smoking. As a result, she continued smoking despite developing airflow limitation and severe emphysema. She was subsequently found to have alpha 1 anti-trypsin deficiency. She later noticed that she could get a similar benefit in her colitis with nicotine chewing gum as she had with cigarettes. For patients with smoking-responsive ulcerative colitis, non-tobacco forms of nicotine delivery such as gum or transdermal patches should be considered to avoid the hazards of cigarette smoke.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Watson JP,Lewis RA

doi

10.1016/0954-6111(95)90235-x

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

635-6

issue

9

eissn

0954-6111

issn

1532-3064

pii

0954-6111(95)90235-X

journal_volume

89

pub_type

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