Abstract：
:Whereas recent research has demonstrated clear evidence for beneficial effects of early referral to the nephrologist in chronic renal insufficiency in adults, no such data exist for the pediatric population. In this study, we therefore correlated patient age and residual renal function at first presentation to a specialized pediatric nephrologist with the extent of secondary uremic complications and the further course of renal function. From March 2003 until March 2004, 43 children (34 boys, aged 10.1 +/- 6.3 yrs) with congenital-urologic (n = 26), congenital-nephrologic (n = 13) or acquired (n = 4) renal diseases had been followed for 3.9 yrs (14 days to 17.5 yrs) at the Kinderdialyse Wien, with a residual renal function of 35 +/- 20.5 ml/min/1.73 m(2) at first presentation. With regards to uremic secondary complications, the majority of children exhibited involvement of at least two systems at first presentation. Thereafter, children with congenital diseases who were referred to the specialized pediatric nephrology unit within the first year of live demonstrated a significantly better course of residual renal function (1.8% vs -0.7%, p = 0.034) than children who were referred later. These data confirm recent registry reports on chronic renal insufficiency in children. Only about a third of the children of our population were presented to a specialized pediatric nephrology center within their first year of life (despite a congenital disease in 90% of them). Thus, therapeutic interventions might be currently offered at a delayed time point in the majority of children.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Böhm M,Arbeiter K,Müller T,Raffelsberger N,Falger J,Balzar E,Aufricht Cdoi
10.1007/s00508-005-0458-0subject
Has Abstractpub_date
2005-10-01 00:00:00pages
702-6issue
19-20eissn
0043-5325issn
1613-7671journal_volume
117pub_type
杂志文章abstract：:The application of hybridoma technology to the preparation of monoclonal antibodies has had a strong stimulatory effect on many areas of virological research. This development has expanded our knowledge with respect to antigenic variation among viruses and detailed analysis of complex antigenic structures of virus pro...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1985-03-01 00:00:00
abstract：:Peroxisomes were the latest subcellular organelles to be discovered. For a long time, due to limited knowledge of their function, peroxisomes were considered to play only a supporting role for other organelles in cellular metabolism. The discovery of specific metabolic pathways carried out exclusively in peroxisomes a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
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更新日期：1995-01-01 00:00:00
abstract：:During routine anatomical dissection we found an unusual case of origin of the right bronchial artery from a common stem with the inferior thyroid artery, which arose from the internal thoracic artery. Anatomical variations of the origin of bronchial arteries are very frequent and numerous, and their recognition may b...
journal_title：Wiener klinische Wochenschrift
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更新日期：2004-01-01 00:00:00
abstract：:We report our initial experience with pulmonary function testing in neonates during intensive care, using an automated, computerized system (PEDS), which allows non-invasive and rapid determination of pulmonary mechanics and energetics such as compliance, resistance and respiratory drive, and measurement of lung volum...
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更新日期：2001-01-15 00:00:00
abstract：:Enzyme-cytophotometrical investigations allow evaluation of enzyme activity within single, morphologically classified cells. Special problems like development of blood cells, bone marrow cells or of macrophages may thus be studied. Knowledge about the kinetics of granulopoiesis allows a better understanding of altered...
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journal_title：Wiener klinische Wochenschrift
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journal_title：Wiener klinische Wochenschrift
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journal_title：Wiener klinische Wochenschrift
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journal_title：Wiener klinische Wochenschrift
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更新日期：1996-01-01 00:00:00
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journal_title：Wiener klinische Wochenschrift
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journal_title：Wiener klinische Wochenschrift
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更新日期：1999-07-30 00:00:00
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journal_title：Wiener klinische Wochenschrift
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更新日期：1979-07-13 00:00:00
