[Smoking is a risk factor for spinal diseases. Hypothesis of the pathomechanism].

Abstract:

:Epidemiological studies strongly imply that smoking is a risk factor for back problems. The question arises as to the nature of the underlying pathomechanism. Several theories are currently discussed in the literature: it could be due to "unhealthy" life styles associated with smoking, to a rise in intraabdominal pressure caused by frequent coughing, or to osteoporosis of smokers. All of these hypotheses, however, do not stand up to a critical examination of the experimental evidence. A new theory is, therefore, put forward, claiming that smoking leads to malnutrition of the discs, which in turn renders them more vulnerable to mechanical stress. Malnutrition can be brought about by CO-Hb formation, vasoconstriction, arteriosclerotic vessel wall changes, impairment of fibrinolytic activity and changes in the flow properties of blood, all of which are known effects of smoking. The evidence for these pathomechanisms is discussed. Future studies should test the above hypothesis experimentally.

journal_name

Wien Klin Wochenschr

authors

Ernst E

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

626-30

issue

20

eissn

0043-5325

issn

1613-7671

journal_volume

104

pub_type

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    authors: Kähler CM,Högl B,Habeler R,Brezinka C,Hamacher J,Dienstl A,Prior C

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  • [Prevalence and severity of bronchial asthma, allergic rhinitis and atopic dermatitis in Salzburg school children].

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    authors: Aichner F,Bauer G,Gerstenbrand F,Pallua A

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    authors: Fischer G,Speiser P

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    更新日期:1987-10-23 00:00:00

  • [Video-assisted thoracic surgery].

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  • [Sentinel node biopsy in breast cancer: techniques and indications].

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  • [Diagnosis, therapy and follow up of diabetic eye disease].

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  • [The kinetics of bacterial killing by fluctuating concentrations of antibiotics].

    abstract::Differences in kill kinetics and the regrowth pattern of bacteria under the influence of various antibiotics are frequently not represented by their MIC values. The area under the concentration curve represents antimicrobial activity more accurately than the peak concentration. Readministration of antibiotics should o...

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  • [Human placental lactogen and chorionic gonadotropin in diabetic pregnancies (author's transl)].

    abstract::Serial determinations of serum HPL and HCG levels were carried out in 68 diabetic women during the whole course of pregnancy. In diabetic pregnancies of the type B--D according to White's classification, HPL levels were significantly lower than control values from the 10th to the 22nd week. In diabetic pregnancies of ...

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    abstract::Diphyllobothriosis is infestation with the fish tapeworm. Although the worldwide incidence has decreased in recent decades, increased travel and the new popularity of dishes involving raw fish (e.g. sushi) may provide a higher risk of infestation in formerly low-risk areas. We report an Austrian fisherman who passed a...

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  • Do clinical guidelines improve management of sepsis in critically ill elderly patients? A before-and-after study of the implementation of a sepsis protocol.

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  • [Hepatitis delta virus infection: an immunohistochemical study].

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  • [The lung phospholipid content in newborn infants with idiopathic respiratory distress syndrome in relation to lung histology and survival time (author's transl)].

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    doi:

    authors: Krepler R,Davidovits A,Eckerstorfer R,Denk H

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    authors: Mitro P,Šimurda M,Müller E

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  • [Alcohol-induced type V hyperlipidemia in relation to changes in the chemical composition of HDL2].

    abstract::Alcohol consumption is one of the most common causes of secondary hyperlipidaemia in man, but not all alcohol addicts display hyperlipidaemia. 10 healthy male controls were compared with three groups of patients. The first group consisted of 9 heavy drinkers exhibiting type V hyperlipidaemia under the influence of alc...

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    authors: Breier C,Lisch HJ,Braunsteiner H

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  • Thrombolytic therapy and its combination with transluminal catheter dilatation.

    abstract::The material for complete occlusion of an artery is predominantly thrombotic. The longer the occluded segment the worse are the results of PTA since the thrombotic material is not compressible. As long as this thrombotic material is not already organized, it can be lysed by thrombolytic therapy, and thus removed. Rema...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

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    authors: Hess H

    更新日期:1985-01-18 00:00:00

  • [Effect and effectiveness of iodine brine baths in a spa].

    abstract::On the occasion of closing the research department of the Paracelsus Institute in the iodine salt spa, Bad Hall, the results of more than 30 years' research work in this institute are summarized. This work concerned the therapeutic effects of iodine on circulatory illnesses, especially hypertension, bronchitis and deg...

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    pub_type: 杂志文章,评审

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    authors: Eichler I,Winkler R

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    pub_type: 历史文章,杂志文章

    doi:

    authors: Weghaupt K

    更新日期:1975-07-18 00:00:00

  • [Value and significance of obstetric monitoring methods].

    abstract::In a retrospective study on 224 births, 200 continuous tracings recorded during intrapartum cardiotokography were analysed for the presence of alarm signals and the incidence of fetal acidosis assessed by fetal blood sampling. Moreover, we classified the 200 monitored parturitions according to the presence of risk at ...

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    pub_type: 杂志文章

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    authors: Schröck A

    更新日期:1988-03-04 00:00:00