Abstract：
:Madelung's disease, or multiple symmetric lipomatosis, is an extremely rare disease and very likely to be under-diagnosed. It is characterized by multiple symmetrical non-encapsulated fat accumulations mainly located around the neck, shoulders, upper extremities and upper parts of the trunk. The disorder predominantly affects middle-aged men of Mediterranean origin with a history of ethanol intake. Reports of this uncommon disorder in women are very rare. The aim of this article is to report the endocrine and metabolic workup leading to the diagnosis of this uncommon disorder. A 55-year-old woman with osteoporosis was referred to our outpatient clinic with a suspected diagnosis of Cushing's disease. The patient complained of undesired weight gain with atypical fat accumulations predominantly in the upper trunk region during the previous 10 weeks. She presented with the characteristic physical features of Madelung's disease and underwent a thorough examination with endocrine and metabolic evaluation of this rare condition and was finally diagnosed with Madelung's disease. This report demonstrates how a diagnosis of this rare disorder can be reached efficiently. A history of osteoporosis in combination with weight gain and atypical fat accumulations ultimately led to the diagnosis of Madelung's diseases, a rather unknown disorder likely to be under-diagnosed. Although treatment options are limited, a diagnosis is still important for the affected individual.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Friedl C,Sampl E,Prandl EC,Wagner D,Piswanger-Soelkner JC,Rosenkranz AR,Fahrleitner-Pammer Adoi
10.1007/s00508-011-0045-5subject
Has Abstractpub_date
2012-03-01 00:00:00pages
188-92issue
5-6eissn
0043-5325issn
1613-7671journal_volume
124pub_type
杂志文章abstract：:Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient. The patient's expectations of this confidence are: the doctor will not act without the patient's consent and the doctor will not undertake any measure to shorten the patient's life. The patient is strengthened in this confi...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1990-10-12 00:00:00
abstract：:Childhood IQ and adult morbidity and mortality are known to be linked even beyond socioeconomic variables. Yet, their interrelations are insufficiently understood. It has been suggested that bodily sensations play a fundamental role in health-related self-regulation and that intelligence can influence the information ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-010-1481-3
更新日期：2010-12-01 00:00:00
abstract：:Cardiogenic shock (CS) is defined as end-organ hypoperfusion as the consequence of primary myocardial dysfunction. Among the diagnostic criteria are a systolic blood pressure < 90 mmHg, acute renal failure (oligoanuria), ischemic hepatitis, cyanosis and cold, clammy skin. Accepted hemodynamic cutoffs are a cardiac ind...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01612-1
更新日期：2020-06-01 00:00:00
abstract：:What clinicians expect from computers is contrasted with the actual potency of computerized data analysis. Different paths of procedure and the resulting chances of satisfactory implementation are discussed in the light of several specific cases. Additionally, examples are given both of highly efficient solutions and ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1987-11-20 00:00:00
abstract：:Cold-insoluble globulin (CIG) of plasma represents the soluble form of a fibroblast surface protein. As shown by affinity chromatography it is selectively adsorbed from plasma on immobilized collagen of various types. The following sequence of binding strength between CIG and collagen was evaluated by means of fractio...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-11-11 00:00:00
abstract：:The Vienna Heart, a pulsatile artificial ventricle, vacuum-formed from Pellethane has been used successfully as total artificial heart (TAH) and left ventricular assist device (LVAD) to bridge over patients in terminal heart failure. A 50 year-old patient with cardiomyopathy had to be resuscitated and was transferred ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Non-syndromic autosomal dominant hearing impairment is characteristically postlingual in onset. Genetic diagnostics are essential for genetic counselling, disease prognosis and understanding of the molecular mechanisms of disease. To date, 36 causative genes have been identified, many in only individual fami...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-017-1230-y
更新日期：2018-05-01 00:00:00
abstract：:Over the past two to three years video-assisted thoracic surgery has opened up new possibilities in diagnostic and therapeutic procedures. It is viewed as a sparing and quick alternative to thoracotomy and open operation for a number of indications including the treatment of pneumothorax, obtaining biopsies of undiagn...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:Because of the high frequency of acute hemodynamic deterioration in patients awaiting cardiac transplantation, mechanical techniques of circulatory support to bridge the period until transplantation have become a standard clinical procedure. Continuous-flow rotary blood pumps offer exciting new perspectives in terms o...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1999-09-03 00:00:00
abstract：:Recent advances in pulmonary physiology have led to new concepts in the understanding of childhood respiratory disorders. The functional development of the respiratory system appears responsible for most of the age-related attributes of pediatric lung diseases. Increased understanding of the altered physiology of thes...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1983-01-07 00:00:00
abstract：:Sentinel node biopsy (SNB) has proved to be a useful and accurate procedure for lymph node staging in breast cancer and melanoma and should be standard of care in the treatment of these tumors. In other malignancies (colon, rectum, stomach, esophagus, head and neck and thyroid, cervix uteri) it is still under investig...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-005-0320-4
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:To retrospectively compare the clinical outcome in cervical cancer patients treated by external irradiation and intracavitary high-dose rate (HDR) brachytherapy with iridium 192 versus low-dose rate (LDR) brachytherapy with radium 226 or caesium 139. METHODS:450 LDR patients were treated from 1982 to 1986 a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2001-01-15 00:00:00
abstract：:Indirect mesentericoportography was performed in 36 patients after administration of prostaglandin E1 and immediately before contrast medium injection. The results were compared with the findings in a control group of 20 patients receiving tolazoline as vasodilator. On comparing prostaglandin E1 with tolazoline no sig...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章
doi：
更新日期：1985-09-13 00:00:00
abstract：:Insulin resistance is a common characteristic of women with polycystic ovary syndrome (PCOS) who are known to differ in their in-vitro fertilization outcomes compared to non-PCOS patients. As insulin resistance can be found in a considerable proportion of normal individuals, we assessed its contribution to ovarian res...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-06-28 00:00:00
abstract：:The prevalence of problem-drinking and alcohol dependence in Austria was assessed on the basis of two random samples of the general population drawn in 1995 (n=216) and in 1996 (n=531). Measurements were performed using the CAGE questionnaire (Mayfield et al. 1974). Both cut-off points (> or = 1, > or = 2) of the CAGE...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1998-05-22 00:00:00
abstract：AIM:Guidelines for the management of sepsis have been published but not validated for elderly patients, though a prompt work-up and initiation of appropriate therapy are crucial. This study assesses the impact of a sepsis protocol on timelines for therapy and mortality in standardized management. METHODS:Consecutive p...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章
doi：10.1007/s00508-012-0229-7
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Facial nerve palsy is a rare complication of acute otitis media (AOM). The general understanding is that this complication has a bacterial cause although bacteria can be isolated from the middle ear only in approximately two-thirds of cases of AOM. Detection of viral agents from specimens obtained during myr...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-017-1259-y
更新日期：2017-11-01 00:00:00
abstract：:Diphyllobothriosis is infestation with the fish tapeworm. Although the worldwide incidence has decreased in recent decades, increased travel and the new popularity of dishes involving raw fish (e.g. sushi) may provide a higher risk of infestation in formerly low-risk areas. We report an Austrian fisherman who passed a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-005-0463-3
更新日期：2005-11-01 00:00:00
abstract：:This paper presents the results of a combined endoscopic-surgical approach with management of acute biliary pancreatitis in 91 patients. The diagnosis was always made by means of endoscopic-retrograde cholangiography. Papillary or bile duct stones, or unmistakable signs of previous stone passage, and in exceptional ca...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:The aim of our study was to determine whether a difference exists in expression of corticotropin-releasing hormone receptor-R1 (CRH-R1) and corticotropin-releasing hormone receptor-R2 (CRH-R2) in fetal membranes of preterm and term women with or without labor. MATERIAL AND METHODS:Small pleces of fetal membr...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-12-30 00:00:00
abstract：OBJECTIVE:To identify predictors of students' success in the first-year exam in a new curriculum in the study of medicine in Vienna. DESIGN:We tested 11 topics (including socio-demographic variables, family background, school performance, economic situation, living conditions, social integration and health, learning c...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-005-0477-x
更新日期：2005-12-01 00:00:00
abstract：:The inscription on Paracelsus' epitaph in the cemetery of Saint Sebastian in Salzburg is critically reviewed with regard to an allusion to Job, Chapter 19. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1989-02-17 00:00:00
abstract：:The contribution of Albert Wiedmann (1901 to 1970) towards the development of the Viennese Dermatological School are evaluated. The following main points of interest can be focused out of a large number of scientific papers; investigations in the field of venerology, innervation and nutrition of the skin (concept of t...
journal_title：Wiener klinische Wochenschrift
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1981-12-25 00:00:00
abstract：:A case of aneurysm of the abdominal aorta is presented. The clinical picture was suggestive of a pancreatic cyst, but the correct diagnosis was made on abdominal ultrasonography. Early diagnosis of the condition allowed removal of the aneurysm and implantation of a femoral by-pass. The value of ultrasonography in diag...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-01-05 00:00:00
abstract：:Bone mineral content (BMC) of the lumbar spine (L2-L4), femoral neck, Ward's triangle and the trochanteric region was measured in 52 consecutive patients on maintenance haemodialysis. In the whole group the median BMC value as percentage of sex- and age-matched normal means was significantly decreased only in Ward's t...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1990-03-02 00:00:00
abstract：:Side effects of vaccinations can have different causes. Substances admixed to vaccines may produce allergic or toxic reactions. The significance and importance of causal associations is discussed in this paper. A table is added listing the most important substances in vaccines, such as inactivating substances, preserv...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-005-0405-0
更新日期：2005-08-01 00:00:00
abstract：:The enormous contributions of Professor Karl Landsteiner are summarized focusing on his discovery of the ABO, MN, and P blood group systems as well as his conceptualization of the hapten concept. The HLA system, the major histocompatibility complex in humans, is discussed from the point of view of its genetic organiza...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Proteinuria in Heymann's nephritis, an experimental rat model disease corresponding to membranous nephropathy, has been shown to be due to lipid peroxidation. Since the pathophysiology might be similar to idiopathic membranous nephropathy in humans, we performed a prospective multicenter trial to investigate...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,多中心研究
doi：
更新日期：2002-02-28 00:00:00
abstract：:Alcoholism is usually understood as ethanolism. There is some evidence that its oxidation product acetaldehyde may condense with endogenous amines to form tetrahydroisoquinoline (TIQ) and - tetrahydro-beta-carboline (THBC) alkaloids which ultimately might be responsible for addiction. In most animal experiments pure e...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1988-04-29 00:00:00
abstract：:We report about an 18-year-old man, suffering from acne on his face and trunk and complaining about indefinite bone pains--without any trauma. SAPHO-syndrome was diagnosed which consists of synovitis, acne, pustulosis, hyperostosis and osteitis. Five types of this syndrome can be differentiated: spondarthritis hyperos...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-05-15 00:00:00
