Abstract:
:Because of the high frequency of acute hemodynamic deterioration in patients awaiting cardiac transplantation, mechanical techniques of circulatory support to bridge the period until transplantation have become a standard clinical procedure. Continuous-flow rotary blood pumps offer exciting new perspectives in terms of ventricular assistance and/or as a total cardiac substitute. A DeBakey VAD axial flow pump was implanted in two male patients (aged 44 and 65 years, respectively) suffering from end-stage left heart failure. In the initial postoperative period the mean flow rate of the pump was 3.9 +/- 0.5 l/min. In both patients, the early postoperative phase was characterised by a completely non-pulsatile flow profile. Two weeks after implantation and partial recovery of the natural left ventricle, increasing pulse pressures became evident and net flow increased to 4.5 +/- 0.6 l/min. Patients were mobilised and made to under-go regular physical training. Hemolysis produced by the pump was low while free haemoglobin stayed in physiological ranges, increasing only slightly from 2.1 +/- 0.8 mg/dl preoperatively to 3.0 +/- 1.5 mg/dl ten weeks after implantation. One patient was successfully transplanted on day 74 after implantation of the DeBakey VAD while the second patient is, after 110 days of pumping, still waiting for transplantation. This first experience concerning clinical implantation of the DeBakey VAD axial flow pump showed that the device is promising as a means of providing mechanical support to bridge the period until cardiac transplantation.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Wieselthaler GM,Schima H,Lassnigg A,Pacher R,Ovsenk T,Laufer G,Noon GP,DeBakey ME,Wolner Esubject
Has Abstractpub_date
1999-09-03 00:00:00pages
629-35issue
16eissn
0043-5325issn
1613-7671journal_volume
111pub_type
杂志文章abstract::High levels of CA-125, the specific tumour marker for epithelial ovarian cancers are also found in inflammatory diseases of the pelvis. This case report of a 28 year-old woman with pathological CA-125 levels demonstrates the association between this finding and ascites caused by miliary tuberculosis. Tuberculostatic c...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1989-12-22 00:00:00
abstract::High-dose corticoid therapy was assessed in 36 patients with end-stage cancer of various different types. These patients were compared with a control group of patients with terminal cancer on a conventional palliative regimen without corticoid therapy. Euphoria, a decrease in the required dose of analgetic and psychop...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-07-06 00:00:00
abstract::The Vienna Heart, a pulsatile artificial ventricle, vacuum-formed from Pellethane has been used successfully as total artificial heart (TAH) and left ventricular assist device (LVAD) to bridge over patients in terminal heart failure. A 50 year-old patient with cardiomyopathy had to be resuscitated and was transferred ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::In the course of routine gastroduodenoscopic examination of 218 patients bioptic mucosal specimens were examined bacteriologically for the presence of Campylobacter (C.) pylori. The organism was isolated from 52 out of 53 patients (98%) with duodenal ulcer, 7 out of 9 with gastric ulcer (78%), 24 out of 31 with mucosa...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-07-17 00:00:00
abstract::The value of plate thermography in the determination of placental localization was investigated in 120 cases, and compared with the results obtained by the ultrasonic B-Scan method. The duration of pregnancy in these cases ranged from 15 to 37 weeks. The results of plate thermography corresponded with ultrasonic local...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-11-14 00:00:00
abstract::This study analyses the efficacy of a consistent, strict follow-up programme in the management of patients with gastric cancer. Between 1978 and 1986 671 patients were treated, of whom 361 (54%) had a radical operation. The data were fed into an electronic data base and patients were invited to attend the follow-up in...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-06-12 00:00:00
abstract::In this study 36 patients with cardiac phobia were examined prior to hospitalisation and 29 of them were re-examined after 2.5 years. An analysis of the clinical pictures showed that all of the patients met the DSM III criteria for panic disorder. The follow-up results indicated that the anxiety attacks often recurred...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-08-28 00:00:00
abstract:OBJECTIVES:To evaluate the impact of oral health on the evolution of nosocomial infections and to document the effects of oral antiseptic decontamination on oral health and on the rate of nosocomial infections in patients in a surgical intensive-care unit (ICU). DESIGN:A prospective, randomized, double-blind, placebo-...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00508-010-1397-y
更新日期:2010-07-01 00:00:00
abstract::During the last decades a sharp increase in the occurrence of invasive aspergillosis associated with a high mortality has been observed. This fact is mainly due to an increase in the number of immunosuppressed patients. Nosocomial aspergillosis usually is of exogenous origin and often related to building construction ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-05 00:00:00
abstract::Multiple endocrine neoplasia type 1 (MEN1) is a rare cancer predisposition syndrome. It results from the autosomal dominant inheritance of inactivating germ-line mutations of the MEN1 tumor suppressor gene. Mutation carriers are prone to develop tumors, preferentially, of the parathyroid and anterior pituitary glands ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2002-04-15 00:00:00
abstract::Between 1969 and 1980 296 patients with cervical cancer were treated by surgery in our department and some were given postoperative irradiation. The five-year survival rate was 96.2% in stage I a cases and 85.2% in stage Ib. The surgically obtained specimens were evaluated for tumour extension and lymph node spread. T...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-05-15 00:00:00
abstract::In 110 patients receiving a long-term anticonvulsant monotherapy with Diphenylhydantoin (DPH) and Carbamazepine (CBZ) the serum activities of gamma-GT, ASAT, ALAT, and AP were examined retrospectively. Elevated serum levels of enzymes were seen predominantly concerning gamma-GT and AP. 91% resp. 39% of patients receiv...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-10-21 00:00:00
abstract:BACKGROUND:In the second half of the 20th century the medical profession has changed considerably. "The golden age of medicine" seems to be over. This study analyses job satisfaction and prospects of Austrian physicians in the twenty-first century. METHODS:A questionnaire was sent to all 289 internal medicine speciali...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-007-0843-y
更新日期:2007-01-01 00:00:00
abstract::Cholelithiasis is a rare, but important condition to be considered in the differential diagnosis of abdominal symptoms in childhood and adolescence. A survey over a 20-year period revealed 10 cases between the ages of 11 and 20 years, with a clinical history of cholelithiasis of between 5 days and 6 years. The most co...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-10-28 00:00:00
abstract::Lipolytic activity was measured under different conditions in isolated fat cells and homogenates of human adipose tissue of the greater omentum. It was demonstrated that lipolysis took place in isolated fat cells at an optimum pH of 7.4 and was markedly stimulated by noradrenaline, but not by blood serum. By contrast ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-01-23 00:00:00
abstract::The National Lung Screening Trial (NLST) could demonstrate, for the first time, in a prospective randomized trial, that low-dose CT screening (LD-CT) may decrease lung cancer mortality. At the moment, it is unclear how these results will be applicable to Austria. Specifically, the definition of the population at an in...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-013-0356-9
更新日期:2013-06-01 00:00:00
abstract::The possibility of determining the blood levels of antiepileptic drugs represents a considerable advance, under certain circumstances, objective supervision of anticonvulsant therapy. In particular in the case of an unsatisfactory therapeutic result, this procedure helps to reveal the causes of failure (e.g. incorrect...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-08-10 00:00:00
abstract::On the occasion of closing the research department of the Paracelsus Institute in the iodine salt spa, Bad Hall, the results of more than 30 years' research work in this institute are summarized. This work concerned the therapeutic effects of iodine on circulatory illnesses, especially hypertension, bronchitis and deg...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:We used efficacy data from three clinical trials to investigate the pharmacoeconomic implications of treating noninstitutionalized Austrian dementia patients with a drug based on EGb 761R, a standardized extract from Gingkgo biloba. In a separate analysis, we compared the pharmacoeconomic aspects of achieving...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,meta分析
doi:10.1007/s00508-012-0307-x
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Liver disease impacts on hepatic synthesis of lipoproteins and lipogenesis but data on dyslipidemia during disease progression are limited. We assessed the patterns of dyslipidemia in (i) different liver disease etiologies and discriminated (ii) non-advanced (non-ACLD) from advanced chronic liver disease (AC...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-01544-5
更新日期:2019-09-01 00:00:00
abstract::The immunohistological findings are reported in 62 cases of malignant lymphomas, pseudolymphomas and malignant histiocytic disorders of the skin. Paraffin-embedded tissue was analyzed with the Peroxidase-Antiperoxidase (PAP) Technique for the presence of intracytoplasmic immunoglobulin (IgM, IgA, IgG, Kappa, Lambda) a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-09-04 00:00:00
abstract::Concomitant hydrocortisone and arginine vasopressin therapy increases arginine vasopressin plasma levels and may improve survival in septic shock. The objective of this post hoc analysis of a prospective study was to determine whether hydrocortisone therapy increases arginine vasopressin plasma levels in patients with...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-1568-5
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The obesity epidemic might affect patients with type 1 diabetes (T1DM), historically described as lean and insulin-sensitive subjects. Insulin resistance in T1DM might increase diabetic complications, especially cardiovascular disease. Therefore, the body mass index (BMI) in T1DM patients was analyzed in com...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-018-1434-9
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:This study aims to provide empirical data on physicians' intentions in withholding and withdrawing treatment, and to discuss possible implications for the ethical debate. BASIC PROCEDURES:The data presented come from EURELD, a large research project designed to investigate medical end-of-life decisions in six ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-006-0583-4
更新日期:2006-06-01 00:00:00
abstract::Intussusception is a rare clinical finding in adults. Most cases occur in the distal small bowel or large intestine. We report the case of a 65-year-old woman with known non-small-cell lung cancer (NSCLC) who presented with acute abdomen and ileus-like symptoms. Abdominal computed tomography suggested ileocecal intuss...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-009-1146-2
更新日期:2009-01-01 00:00:00
abstract::Insulinoma in a patient with pre-existing diabetes mellitus is extremely rare. We report a case of an insulinoma in a patient with type 2 diabetes mellitus who after 14 years of sulfonylurea treatment experienced recurrent episodes of hypoglycemia. Endogenous hyperinsulinism was confirmed and endoscopic ultrasonograph...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2001-04-30 00:00:00
abstract::After a short review of the development of endoscopic investigations, the technique of gastroscopy is described and the indications for this procedure are pointed out. This procedure is of equal importance as radio-diagnostic measures in the routine investigation of stomach diseases and is of particular value when use...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-09-19 00:00:00
abstract::Disturbances of thyroid function occur more often in the elderly than in the young. This short review gives an up-to-date overview of this topic. After discussing the difference in epidemiology of thyroid dysfunction in elderly persons in areas with different iodine nutrient status, the physiologic age-induced changes...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-005-0504-y
更新日期:2006-02-01 00:00:00
abstract::Evaluation of the hepatitis-B data of the Austrian Workers' Compensation Board (AWCB), where the results of the serological findings of the markers HBsAg, anti-HBs and anti-HBc are stored, allows the following conclusions to be reached regarding persons employed in gynaecological departments: The average hepatitis-B i...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-04-17 00:00:00
abstract::Carnitine was discovered at the beginning of this century, but was nearly forgotten until its importance in fatty acid metabolism was established 50 years later. In the past years, several other functions of carnitine in cellular metabolism have been described. The lung contains more than 40 different cell types, most...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00