Abstract:
:The application of hybridoma technology to the preparation of monoclonal antibodies has had a strong stimulatory effect on many areas of virological research. This development has expanded our knowledge with respect to antigenic variation among viruses and detailed analysis of complex antigenic structures of virus proteins and has also led to the elucidation of the molecular foundations of pathogenesis and virulence in model systems. The practical importance of these results spans many important areas of applied virology such as the development of new viral vaccines, passive immunization and diagnosis of viral infections.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Heinz FXsubject
Has Abstractpub_date
1985-03-01 00:00:00pages
230-7issue
5eissn
0043-5325issn
1613-7671journal_volume
97pub_type
杂志文章,评审abstract:BACKGROUND:Facial nerve palsy is a rare complication of acute otitis media (AOM). The general understanding is that this complication has a bacterial cause although bacteria can be isolated from the middle ear only in approximately two-thirds of cases of AOM. Detection of viral agents from specimens obtained during myr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-017-1259-y
更新日期:2017-11-01 00:00:00
abstract::Our experiences are reported with the "intraprostatic spiral" in 23 high-risk patients with prostatic adenoma. The intraprostatic spiral was used only in selected patients for medical indications. Patients confined to bed as well as those with detrusor instability or secondary dilatation of the upper urinary tract wer...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-11-09 00:00:00
abstract::Travellers' diarrhoea is the most likely cause for disturbing travel arrangements. At an average, 30-40% of tourists are concerned, depending on the travel destination. Due to the high impact on the travellers' health this topic is still of utmost importance in travel medicine. A wide spectrum of enteropathogens can b...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-009-1228-1
更新日期:2009-10-01 00:00:00
abstract::Several pathogenic mycoplasma species are known etiologic agents of diseases in man and animals, which typically involve the respiratory tract, urogenital tract and joints and often show chronicity. Although the basis for this chronicity is not well understood, it is apparent that several species of pathogenic mycopla...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1997-08-08 00:00:00
abstract::Endurance training after myocardial infarction results in increased fitness and favours regression of coronary arteriosclerosis if the intensity of the training programme results in an expenditure of at least 2200 Kcalories per week. During physical exercise the risk of sudden death is increased, however the net effec...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Borrelia lusitaniae was isolated from an Ixodes ricinus tick in Portugal in 1993 for the first time. Further, this borrelia genospecies has been found in ixodid ticks collected around the coasts of southern Portugal and North Africa. Its reservoir has not been defined yet. B. lusitaniae was isolated once unt...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-005-0386-z
更新日期:2005-06-01 00:00:00
abstract::In a prospective study comprising 48 children (21 boys, 27 girls, age 12 months to 15 years) the hypothesis was tested whether an alteration in the light chain immunoglobulins kappa (kappa) and lambda (lambda) is an expression of autoimmune mechanisms and could be used as a diagnostic parameter. Immunoglobulins were a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-04-13 00:00:00
abstract::In two groups of pts with diabetic derangements the effect of infusion therapy was investigated with regard to metabolic and endocrine functions. The rate of infusion was adapted to the height of the central venous pressure and the administration of electrolytes to their serum concentration. Insulin was withheld until...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1980-09-12 00:00:00
abstract:OBJECTIVE:To present our innovative surgical method for prevention of early preterm delivery in women with cervical dilatation and membrane herniation. STUDY DESIGN:A woman in the 24th gestational week, with membrane herniation due to a 2-3 cm dilatation of the cervix, is presented. The surgical technique for occlusio...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-006-0550-0
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To review the diagnosis and the treatment of both subclinical and overt hypothyroidism in old people, which could represent a challenge for the clinicians. METHODS:Narrative literature review. An extensive literature search was performed using the databases of Scopus, Medline through PubMed, and Google Scholar...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-019-01579-8
更新日期:2020-03-01 00:00:00
abstract::Twenty-one patients with an average age of 69 years were subjected to endoscopic sphincterotomy of the papilla of Vater over the past six months. This therapeutic approach was successful and without ensuring complications in 20 of these patients. Hence, endoscopic sphincterotomy can be recommended in the case of elder...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-06-08 00:00:00
abstract::To evaluate the impact of the increase in consultation fees on malaria incidence in children presenting in the outpatient clinic of a privately funded hospital, we measured the impact of two fee increases on the number of pediatric outpatients. A 74% reduction in outpatients and a 78% reduction in malaria cases occurr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040905
更新日期:2004-05-31 00:00:00
abstract::Diabetes mellitus causes diabetic retinopathy, diabetic macular edema, optic neuropathy, cataract or dysfunction of the eye muscles. The incidence of these defects correlates with disease duration and quality of the metabolic control. The recommendations of the Austrian Diabetes Association for the diagnosis, the ther...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-012-0272-4
更新日期:2012-12-01 00:00:00
abstract::Prospective epidemiological studies have proven a close link between the improvement of the lipoprotein profile and reduction of coronary heart mortality in coronary heart disease (CHD) patients. Both, regular physical activity and pharmacological intervention are capable of improving the lipoprotein profile and may i...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::In a prospective study, 60 patients with allergic rhinoconjunctivitis and/or asthma due to house dust mites were chosen for hyposensitization treatment with Migen (M) or Pharmalgen (P). Immunotherapy stretched over a whole year and every 3 months clinical results were evaluated by the patient's symptom score, by resul...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-08-04 00:00:00
abstract:BACKGROUND:Rising costs of pharmaceuticals are a challenge to the public health care system. In collaboration with a company health insurance with 3143 members we analysed the economic benefit of reduced prescription fees for generic drugs in a 12-month period. METHODS:Within the observation period 1 euro per prescrip...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-007-0890-4
更新日期:2008-01-01 00:00:00
abstract::The immunohistological findings are reported in 62 cases of malignant lymphomas, pseudolymphomas and malignant histiocytic disorders of the skin. Paraffin-embedded tissue was analyzed with the Peroxidase-Antiperoxidase (PAP) Technique for the presence of intracytoplasmic immunoglobulin (IgM, IgA, IgG, Kappa, Lambda) a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-09-04 00:00:00
abstract::In a prospective study 73 patients on maintenance digitalis treatment at the Paracelsus Institute, Bad Hall, were clinically examined and the dosage of the drug was adjusted according to cardiac symptoms. The clinical effects were correlated to digoxin concentrations measured on the day following admission to hospital...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-03-16 00:00:00
abstract::Tobacco smoking is the major cause of lung disease. This study aimed to determine: 1) the prevalence of tobacco smoking among office-based physicians; 2) their readiness to inquire about their patients' smoking habits and, if need be, to motivate them to stop smoking; 3) whether non-smoking doctors advise their patien...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2002-09-30 00:00:00
abstract:BACKGROUND AND AIM:Nonalcoholic fatty liver diseases (NAFLD) are a clinical spectrum of disorders, of which nonalcoholic steatohepatitis (NASH) is the most strongly associated with inflammation. Inflammation is a known risk factor for low bone mass in the body. The primary goal of the present study was to evaluate the ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-012-0211-4
更新日期:2012-08-01 00:00:00
abstract::Since 1997 minimally invasive surgical techniques are used for the treatment of diseases of the adrenals, thyroid, parathyroid and the endocrine pancreas. In contrast to open surgical procedures special radiological examinations are the basis for minimally invasive techniques after biochemical testing. The basis of ex...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract::Plasma renin, adrenaline and noradrenaline were measured by the respective radioenzymic and radioimmunological methods in 69 patients with essential hypertension, 40 patients with secondary hypertension from chronic parenchymatous renal disease and in 18 normotensive controls. Plasma levels of adrenaline and noradrena...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-05-15 00:00:00
abstract::Tick-borne encephalitis is one of the most frequently-encountered virus diseases of the central nervous system in Europe. Hence, prophylactic measures for the prevention of tick-borne encephalitis are of particular importance, especially since it is virtually impossible to influence the course of the manifest disease ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-04-16 00:00:00
abstract:BACKGROUND:Osteoarthritis (OA) of the hip is a frequent and debilitating joint disease. Only few clinical risk factors for hip OA are established and clinically applicable biomarkers to identify patients at risk are still lacking. The glycoprotein vascular cell adhesion molecule 1 (VCAM-1) is expressed by chondrocytes ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-1497-2
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Unrepaired left to right atrial shunt lesions can cause significant right ventricular (RV) volume overload. The parameter pulmonary to systemic shunt volume ratio (Qp:Qs) has been shown to detect even small differences between left and right ventricular stroke volume; however, four parameters are needed for ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-020-01659-0
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Heart failure is associated with low-grade inflammation. In the present study we sought to assess the prognostic impact of orosomucoid, a marker of inflammation, in outpatients with heart failure. METHODS:In outpatients with chronic heart failure (no change in clinical status and/or therapy >3 months prior ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-016-1034-5
更新日期:2016-12-01 00:00:00
abstract::Various chronic pulmonary diseases can cause hypoxia mediated erythrocytosis. We report on a 46 year old male patient presenting with erythrocytosis, in whom a pulmonary arteriovenous fistula on the basis of a vascular malformation was identified as a rare cause of hypoxic erythrocytosis. Thus, congenital pulmonary va...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-11-13 00:00:00
abstract::On the occasion of closing the research department of the Paracelsus Institute in the iodine salt spa, Bad Hall, the results of more than 30 years' research work in this institute are summarized. This work concerned the therapeutic effects of iodine on circulatory illnesses, especially hypertension, bronchitis and deg...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::An attempt must be made to deal with the emotionally disturbed person in the test area of various social relationships, in order to learn to understand better the "language" of his symptoms. Moreover, Adler, Freud and Lorenz taught us to pay special attention to child development. This paper tries to project sexually ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-12-19 00:00:00
abstract::Patients who are unable to be adequately nourished owing to cerebral dysfunction do not tolerate nasogastric tubes for enteral nutrition well. They are threatened by active or passive dislocation of the tube into the oesophagus with subsequent aspiration. Although these risks are minimized by percutaneous gastrostomy ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-05-13 00:00:00