Abstract:
:Plasma renin, adrenaline and noradrenaline were measured by the respective radioenzymic and radioimmunological methods in 69 patients with essential hypertension, 40 patients with secondary hypertension from chronic parenchymatous renal disease and in 18 normotensive controls. Plasma levels of adrenaline and noradrenaline were not statistically different in primary secondary hypertension and were comparable with normotensive controls. Compared with secondary hypertension, only 4% of patients with primary hypertension had a marginally raised plasma noradrenaline, compared with normotensive subjects, only 6% had a definitely raised plasma noradrenaline level. Though absolutely normal, noradrenaline in high renin essential hypertension was significantly higher than in low renin essential hypertension; it correlated neither with age nor blood pressure. Plasma adrenaline was reduced in about 30% of patients with primary and secondary hypertension, leading to a positively skewed frequency distribution; plasma adrenaline correlated positively with heart rate (p less than 0.001), pulse pressure (p less than 0.01) and plasma noradrenaline (p less than 0.01) and negatively with diastolic blood pressure (p less than 0.05). Supine plasma catecholamine levels do not demonstrate differences in adrenergic tone in primary and secondary hypertension and do not add any new evidence for an increased sympathetic tone in primary hypertension. In fact, plasma adrenaline is suppressed in about 30% of patients with primary and secondary hypertension.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Skrabal F,Auböck J,Hörtnagl H,von Brücke Tsubject
Has Abstractpub_date
1981-05-15 00:00:00pages
321-5issue
10eissn
0043-5325issn
1613-7671journal_volume
93pub_type
杂志文章abstract::A critical review of the relevant literature revealed that the incidence of subarachnoid haemorrhage is increased in women taking oral contraceptives and the mortality rate is higher. The data concerning correlation between the use of oral contraceptives and other cerebrovascular disorders are less conclusive. Taking ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1986-05-16 00:00:00
abstract::The results obtained by closest cooperation between gynaecologist and andrologist in the treatment of sterile marriages are reported. 127 couples were treated over a period of 20 months. Almost 100% of the males and 60% of the females were sub- or infertile. Treatment of both partners was meticulously coordinated in o...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-05-09 00:00:00
abstract::The case of a 53-year-old patient with a 2-year history of Arndt-Gottron scleromyxoedema is reported. Typical lichenoid papules were found clinically, along with infiltration of acid mucopolysaccharides into the skin, which induces extensive elephantine-like thickening and hardening of the skin. The presence of abnorm...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1997-12-23 00:00:00
abstract::The obstetrical management of pregnant women with pregestational diabetes has been significantly improved throughout recent years. In the past, efforts to maintain euglycaemia during pregnancy in the presence of a labile maternal metabolism led to repeated, long-term hospitalization. In an interdisciplinary joint effo...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-04-03 00:00:00
abstract::35 mobilized patients received continuous parenteral nutrition consisting of an all-in-one solution mixed together in this department right before use over a total period of 1155 days (mean per patient 33 days). The primary complication rate was: second puncture in 14%, pneumothorax in 11% and haemothorax in 3% of cas...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1982-08-06 00:00:00
abstract::Between 1969 and 1980 296 patients with cervical cancer were treated by surgery in our department and some were given postoperative irradiation. The five-year survival rate was 96.2% in stage I a cases and 85.2% in stage Ib. The surgically obtained specimens were evaluated for tumour extension and lymph node spread. T...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-05-15 00:00:00
abstract::The material for complete occlusion of an artery is predominantly thrombotic. The longer the occluded segment the worse are the results of PTA since the thrombotic material is not compressible. As long as this thrombotic material is not already organized, it can be lysed by thrombolytic therapy, and thus removed. Rema...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-01-18 00:00:00
abstract::In the small and large intestine Na and Cl are absorbed via active transport systems, whereas K appears to distribute passively between the lumen and the blood side of the epithelium. Three types of Na influx mechanisms across the luminal cell membrane of the epithelium may be distinguished: 1. In the gall bladder and...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-10-10 00:00:00
abstract::The technique of exchange transfusion using a plastic catheter in the umbilical vein developed by Diamond and modified by Allen was instrumental in decreasing the mortality and morbidity in newborn infants with jaundice. Allen et al. demonstrated that the development of kernicterus in infants with erythroblastosis wit...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-08-31 00:00:00
abstract::This review gives a historical overview about the development of today's understanding of benign thyroid diseases and the possibilities of their treatment.Little was known about the thyroid gland until the nineteenth century: the state of knowledge was (1) that something in food, especially in seaweed, avoided the dev...
journal_title:Wiener klinische Wochenschrift
pub_type: 历史文章,杂志文章
doi:10.1007/s00508-014-0515-7
更新日期:2014-05-01 00:00:00
abstract::To obtain a clearer definition of the influence of cardiac disease on the development of cerebrovascular disease (CVD), we carried out a comparative study of two groups of patients, matched for age and sex, one with and one without CVD. These were compared with regard to the incidence of cardiac disease, hypertension ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-06-12 00:00:00
abstract::In a retrospective study on 224 births, 200 continuous tracings recorded during intrapartum cardiotokography were analysed for the presence of alarm signals and the incidence of fetal acidosis assessed by fetal blood sampling. Moreover, we classified the 200 monitored parturitions according to the presence of risk at ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-03-04 00:00:00
abstract:OBJECTIVE AND METHODS:We performed a single center analysis of 60 adult patients (33 males and 27 females) with myelodysplastic syndromes (MDS) or secondary acute myeloid leukemia (AML) who underwent allogeneic hematopoietic stem cell transplantation (HCT) at our institution. RESULTS:Allogeneic stem cell in patients w...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章
doi:10.1007/s00508-013-0449-5
更新日期:2014-01-01 00:00:00
abstract::We present a case of spontaneous recanalization of the internal carotid artery (ICA) that occurred in a 51-year-old male patient. The occlusion of the right ICA was asymptomatic and was detected incidentally during imaging of the opposite carotid artery. The patient underwent neuroradiologic analysis and a tapered, fl...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-010-1490-2
更新日期:2010-11-01 00:00:00
abstract::We report on a 64-year-old patient with a recurrent endometrial carcinoma which was associated with disseminated intravascular coagulation (DIC) and excessive hyperfibrinolysis. The patient presented with severe bleeding due to hypofibrinogenemia. Fibrin degradation products were excessively elevated and there were al...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-01-30 00:00:00
abstract::The labelling of blood cells in vitro for subsequent in vivo studies was one of the earliest applications of radioactive tracers in clinical medicine and laid the foundations for many important contributions to the advancement of knowledge of human blood cell pathophysiology. The characteristics required for satisfact...
journal_title:Wiener klinische Wochenschrift
pub_type: 历史文章,杂志文章
doi:
更新日期:1984-02-03 00:00:00
abstract::Untreated patients with low-grade non-Hodgkin's lymphoma (NHL) demonstrate a natural course of the disease differing from between a few months and decades. Prognostic factors to assess survival probability have recently been defined. Cure seems possible in the rare localized stages by irradiation. In advanced stages w...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Morphological examination of the fundus has improved considerably over the past decade. By means of identation biomicroscopy, hitherto inaccessible, extremely-peripheral areas of the fundus can be examined by the slit lamp now; this of importance in the study of intraocular inflammation and the judgement of retinal te...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1978-06-23 00:00:00
abstract::In part owing to an increasing use of high resolution imaging technologies a growing number of incidental pancreatic lesions are detected. A 40-year-old patient was admitted to our hospital to undergo resection for an unclear solid pancreatic tumor in the pancreatic tail. Preoperative imaging studies suspected an inac...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-1543-1
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Clinical implications of subclinical hypothyroidism (SCH) are still matter of intense debate, resulting in the controversial discussion whether subclinical hypothyroidism should be treated. We performed a cohort study to evaluate the impact of subclinical hypothyroidism on vascular and overall mortality. ME...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-015-0846-z
更新日期:2015-12-01 00:00:00
abstract::This study analyses the efficacy of a consistent, strict follow-up programme in the management of patients with gastric cancer. Between 1978 and 1986 671 patients were treated, of whom 361 (54%) had a radical operation. The data were fed into an electronic data base and patients were invited to attend the follow-up in...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-06-12 00:00:00
abstract::The lipid-reducing effects of bezafibrate and clofibrate were investigated in a double-blind crossover trial. 3 x 200 mg/d bezafibrate and 3 x 500 mg/d clofibrate were administered for periods of 8 weeks each to 22 patients with primary hyperlipoproteinaemia (9 Type IIb, 13 Type IV). Placebo periods preceded and follo...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1980-02-01 00:00:00
abstract::DTIC, a new cytostatic drug developed by the NCI-USA, is described and some relevant pharmacological characteristics are defined. This drug was proved to be the number one choice for the treatment of malignant melanoma and of sarcomas. It also appears to be of value in advanced cases of Hodgkins disease. DTIC represen...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1978-12-22 00:00:00
abstract::A method is described for the purification of horse anti-human lymphocyte serum, whereby absorption of haemagglutinating antibodies was performed with human RBC ghosts. These ghosts were repeatedly used after desorption. Desorption was carried out in glycine-HCl buffer solution pH = 3,0. The advantages of this method ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-05-13 00:00:00
abstract::Acute occlusion of a large coronary artery by a platelet thrombus is a life-threatening event. Intravasal thrombus generation in most cases is caused by a disturbed interaction between platelets and the vessel wall, with accompanying platelet hyperreactivity, local adhesion to the vessel wall, activation and aggregate...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1999-02-12 00:00:00
abstract::The "asthma programme", the product of teamwork between the 1st Department of Dermatology and the 2nd Department of Medicine is presented. It contains all examinations necessary for the diagnosis of bronchial asthma: case history, skin test, IgE, RAST, lung function test, inhalative provocation test. The value of each...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-11-28 00:00:00
abstract::A qualitative cytological study demonstrated that normal cell count in the cerebrospinal fluid does not exclude abnormal cytological findings. Siderophages were found as a late indicator of haemorrhage into the CSF. In some cases of tumours of the CNS sporadic atypical cells were found without other alterations in CSF...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-06-12 00:00:00
abstract::The endocrine management of advanced breast cancer is of great clinical importance. Apart from the known therapeutic approach with oestrogens, androgens, gestagens and steroids, the oestrogen antagonist, tamoxifen appears to be a promising therapeutic agent. In this study from October 1st, 1975, to October 1st, 1976, ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1978-02-17 00:00:00
abstract::A report is given of 135 panendoscopic examinations in acute upper gastrointestinal bleeding. The importance of endoscopy is underlined by the high incidence of erosions and potential bleeding sources, since these lesions are not detected by radiological examination. Nor is it possible by means of X-rays to distinguis...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-10-15 00:00:00
abstract::In a case of disputed paternity mother and child showed a genetic incompatibility in the Kidd system of the erythrocytes: mother Jk(a-b+), child Jk (a+b-). For the first time the RFLP technique solved this problem, using four different Jeffreys' highly polymorphic single locus DNA probes MS 1, MS 31, g 3 and MS 43. We...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-05-11 00:00:00