Abstract:
:We report on a 64-year-old patient with a recurrent endometrial carcinoma which was associated with disseminated intravascular coagulation (DIC) and excessive hyperfibrinolysis. The patient presented with severe bleeding due to hypofibrinogenemia. Fibrin degradation products were excessively elevated and there were also increased levels of activation markers of coagulation. Free plasmin was demonstrated in the circulation and alpha 2-antiplasmin was almost completely depleted. No increase in t-PA or u-PA level was demonstrated. Antifibrinolytic treatment led to a decrease of fibrin degradation products, but to an increase of activation markers of coagulation and was not associated with an increase of fibrinogen. Combination chemotherapy led to a rapid decrease of activation markers of coagulation and a sustained increase of fibrinogen. The beneficial effects on DIC/hyperfibrinolysis occurred despite the absence of any measurable effect of chemotherapy on the tumour. The patient finally died due to progression of the tumour, but without recurrence of the DIC/hyperfibrinolysis.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Weltermann A,Mitterbauer GJ,Mitterbauer M,Hattey E,Speiser W,Gisslinger H,Knöbl P,Eichinger Ssubject
Has Abstractpub_date
1998-01-30 00:00:00pages
53-7issue
2eissn
0043-5325issn
1613-7671journal_volume
110pub_type
杂志文章abstract::The lipid-reducing effects of bezafibrate and clofibrate were investigated in a double-blind crossover trial. 3 x 200 mg/d bezafibrate and 3 x 500 mg/d clofibrate were administered for periods of 8 weeks each to 22 patients with primary hyperlipoproteinaemia (9 Type IIb, 13 Type IV). Placebo periods preceded and follo...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1980-02-01 00:00:00
abstract::Primary, secondary and tertiary prevention are usually differentiated. All preventive measures have to prevail against criteria of effectiveness and efficiency. In the case of primary prevention, the search for risk factors is particularly important. The present limits of prevention of back pain are discussed in some ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Commercially-produced human plasma protein fractions were investigated by a radio-immunological method for their content of Australia antigen (HBsAg). Albumin and gamma globulin solutions in which this antigen was present, were fractionated by isoelectric focussing and gel filtration on Sepharose 4 B. Characterization...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-05-27 00:00:00
abstract::Epidemiological studies strongly imply that smoking is a risk factor for back problems. The question arises as to the nature of the underlying pathomechanism. Several theories are currently discussed in the literature: it could be due to "unhealthy" life styles associated with smoking, to a rise in intraabdominal pres...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::A 66 year-old man with chronic renal failure developed hypercalcaemia during acetolyte medication. A technetium-99m phosphate bone scan at this time showed extraosseous isotope uptake in the stomach, which disappeared 2 weeks later after normalisation of the serum calcium level. This phenomenon can be interpreted as t...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1988-09-23 00:00:00
abstract:BACKGROUND:The aim of this retrospective single center cohort study was to assess the occurrence of bradycardia during implantable loop recorder (ILR) monitoring in patients with unexplained syncope and negative conventional testing and to identify clinical predictors of bradycardia and pacemaker implantation. METHODS...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-017-1197-8
更新日期:2017-07-01 00:00:00
abstract::In a psychophysiological study the spiral after-effect, as measured by means of the Archimedes spiral, was investigated in 182 patients with psychosomatic disorders including duodenal ulcers, ulcerative colitis, anorexia nervosa, asthma and heart neurosis and compared with the results obtained in a control group of he...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1984-08-03 00:00:00
abstract::Dopamine possesses specific pharmacological actions which distinguish it from the other catecholamines. Apart from its positive inotropic effect, dopamine exerts a favourable influence on renal function with an increase in renal blood flow and alterations in intrarenal haemodynamics. The use of dopamine in the early s...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-01-23 00:00:00
abstract::22 children who required respiratory aid (LPPV, CPAP) in the newborn period were followed up to the age of 12 to 36 months. The birth weight ranged between 1050 and 4100 g and the duration of artificial ventilation ranged between 36 and 698 hours. Neurological development of 17 children was completely normal, whilst f...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-09-17 00:00:00
abstract::Thirty four children, aged 2 to 15 years, were treated by haemodialysis between 1967 and 1978. Eleven children suffered from acute renal failure. Twenty three children with end-stage chronic renal disease were treated over periods ranging from 1 week to 19 months. All children were dialysed in a renal unit for adult p...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1980-01-18 00:00:00
abstract::The number and distribution of reactive cells in more than 100 non-Hodgkin lymphomas (NHL) were evaluated in situ in cryostat sections. The results were compared with histological and clinical findings. 40% of the T cell content of normal lymphatic tissues was found in tissues of B-cell NHL. This corresponds to a mean...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::The laser machine and the unique quality of the laser beam are described. The basis of the medical application of laser is its capacity to concentrate large amounts of energy on a small volume of tissue, mostly resulting in thermal coagulation necrosis. The effect of monochromate laser radiation varies, depending on t...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-06-21 00:00:00
abstract::Ovulation was induced in 90 randomly-bred virgin mice (Swiss albino) by the i.p. injection of 5 I.U. pregant mare's serum and human chorionic gonadotropin, respectively, with an interval of 48 hours between injections. Pregnancy occurred in 32 animals following normal fertilization. Caesarian section was generally per...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-01-24 00:00:00
abstract::Cryptosporidium is an important cause of community gastroenteritis, usually associated with drinking contaminated water, visits to swimming pools or animal exposure. In immunocompetent patients, cryptosporidiosis is usually a self-limiting disease but it can be devastating illness in immunocompromised persons. This re...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-006-0637-7
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE AND METHODS:We performed a single center analysis of 60 adult patients (33 males and 27 females) with myelodysplastic syndromes (MDS) or secondary acute myeloid leukemia (AML) who underwent allogeneic hematopoietic stem cell transplantation (HCT) at our institution. RESULTS:Allogeneic stem cell in patients w...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章
doi:10.1007/s00508-013-0449-5
更新日期:2014-01-01 00:00:00
abstract::The ambient ozone concentration has increased greatly over the past decades, which may lead to environmental health problems, especially during the summer. WHO guidelines recommend an 8 hour mean value of < or = 60 ppb ozone without health risk. The aim of the present study was to investigate if elevated zone concentr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1997-05-09 00:00:00
abstract::Recent advances in pulmonary physiology have led to new concepts in the understanding of childhood respiratory disorders. The functional development of the respiratory system appears responsible for most of the age-related attributes of pediatric lung diseases. Increased understanding of the altered physiology of thes...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1983-01-07 00:00:00
abstract::A case of aneurysm of the abdominal aorta is presented. The clinical picture was suggestive of a pancreatic cyst, but the correct diagnosis was made on abdominal ultrasonography. Early diagnosis of the condition allowed removal of the aneurysm and implantation of a femoral by-pass. The value of ultrasonography in diag...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-01-05 00:00:00
abstract:BACKGROUND:Simple renal cysts are frequent findings in mid-aged people, their frequency increases with age. They are often detected by abdominal ultrasound and/or computed tomography during diagnostic procedures. Hypertension is also a frequent disease and its prevalence increases with age as well. The aim of our study...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The plasma levels of hydrocortisone, prednisolone and fluocortolone were studied in healthy males by a competitive protein-binding technique after separation by thin-layer chromatography. Cortisone showed a mean morning level of 440 nmol/l +/- 165 nmol/l and a half life of 4.8 hours. The half life of prednisolone was ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-11-13 00:00:00
abstract::Infection with tick-borne spirochetes (e.g. Borrelia burgdorferi) may lead to the development of erythema chronicum migrans, acrodermatitis atrophicans, meningopolyneuritis Bannwarth, and a special type of reactive arthritis named Lyme disease after the American endemic area. Since these diseases occur also in Austria...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1984-11-23 00:00:00
abstract::Peroxisomes were the latest subcellular organelles to be discovered. For a long time, due to limited knowledge of their function, peroxisomes were considered to play only a supporting role for other organelles in cellular metabolism. The discovery of specific metabolic pathways carried out exclusively in peroxisomes a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Spinal subdural hematoma (SSDH) following spine surgery is an extremely rare condition, with only three cases being reported in the literature. Unintended durotomy has been associated with SSDH due to alterations of pressures in the dural compartments. The objective of the present report was to report two rare cases o...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-014-0632-3
更新日期:2015-01-01 00:00:00
abstract::A well-defined, characteristic disease has been observed in babies at the Department of Dermatology, Innsbruck University, over the past 7 years. On account of the localisation and probable pathogenesis of the condition the term "Windelsoor" (napkin thrush) has been coined by us for it. The clinical picture, the mycol...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-03-07 00:00:00
abstract::We report our experience with primary angioplasty (PPTCA) in acute myocardial infarction performed without prior thrombolytic therapy. Between January 1991 and April 1993, 44 patients underwent PPTCA. Duration of symptoms was 163 +/ 106 min; age range of patients was 30 to 89 years (mean 60.6 +/- 13.5 years). Twelve p...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Hypersensitivity to allergens in tobacco leaf as a cause of occupational asthma in workers of the tobacco manufacturing industry has been reported previously. We describe the case of a female employee working in a tobacco plant with asthmatic symptoms occurring at the working place. The symptoms described by the patie...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::According to the World Health Organization (WHO) the China office was first notified of cases of atypical pneumonia in Wuhan City on 31 December 2019. A viral genome sequence of a novel coronavirus, currently termed SARS-CoV‑2, with a disease process called COVID-19 was released 1 week later via online resources to ob...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-020-01678-x
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:Hypothyroidism (HT) has an increased risk for cardiovascular mortality and morbidity due to increased atherosclerosis. Heart-type fatty acid binding protein (H-FABP) is abundant in the cytosol of cardiomyocytes, and transports fatty acids into these cells. Although H-FABP has been shown to increase in several...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-014-0612-7
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:The development of Alzheimer's disease (AD) can be assessed using the neuropsychological test battery Vienna (NTBV). The objective of this study was to investigate whether the NTBV test scores of a diagnostic group have changed significantly over time and whether this change is due to disease progression. ME...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-020-01755-1
更新日期:2020-10-23 00:00:00
abstract::The case reports are presented of two siblings with familial thymoma. The thymomas developed at the same age in both siblings. The tumours were removed by thoracotomy and classified histologically as identical thymic squamous cell carcinomas. The brother is still alive and well four years after treatment; the sister d...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1983-06-10 00:00:00