Abstract：
BACKGROUND:Osteoarthritis (OA) of the hip is a frequent and debilitating joint disease. Only few clinical risk factors for hip OA are established and clinically applicable biomarkers to identify patients at risk are still lacking. The glycoprotein vascular cell adhesion molecule 1 (VCAM-1) is expressed by chondrocytes and synovial tissue and was a predictive marker for development of severe large joint OA in a previous study. OBJECTIVE:It was tested whether increased serum levels of VCAM-1 are prevalent in patients with severe OA of the hips. METHODS:In this prospective, multicenter, cross-sectional study, risk factors of severe hip OA were investigated in patients scheduled for hip joint arthroplasty and 100 patients were randomly selected for validation of VCAM-1 as a potential biomarker for hip OA. Serum samples were analyzed by an enzyme-linked immunosorbent assay and compared with a sex and age-matched control cohort. RESULTS:The groups were similar in age, gender ratio and prevalence of diabetes. Serum concentrations of VCAM-1 were 8% higher in OA patients compared to controls, without reaching statistical significance (818 ng ml-1, 95% confidence interval, CI 746-891 ng ml-1 versus 759 ng m-1, 95% CI 711-807 ng ml-1; P = 0.4839). CONCLUSION:The results of this study show that serum concentrations of VCAM-1 cannot distinguish patients with severe hip OA from age and sex-matched controls.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Oppl B,Datz C,Huber-Schönauer U,Husar-Memmer E,Brozek W,Zenz P,Gollob E,Wurnig C,Engel A,Klaushofer K,Zwerina J,Bartko Jdoi
10.1007/s00508-019-1497-2subject
Has Abstractpub_date
2019-08-01 00:00:00pages
369-373issue
15-16eissn
0043-5325issn
1613-7671pii
10.1007/s00508-019-1497-2journal_volume
131pub_type
杂志文章abstract：:Skin thickness was measured by means of ultrasound and correlated with the results of bone densitometry and hormonal parameters. Skin thickness and bone density were significantly correlated (p < 0.0001). These results indicated that not only bone, but also skin is a hormone-dependent organ, which responds to the meno...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:This study was undertaken to determine how amniotomy performed during different phases of delivery affects mother and child. 1504 out of 4770 birth recorded during one year at the University Department of Obstetrics and Gynaecology in Graz were analyzed. None of these was associated with the presence of risk factors a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1984-06-08 00:00:00
abstract：:This paper analyzes the birth and death certificate data of infants who died from the Sudden Infant Death Syndrome (SIDS) before their first birthday. It investigates possible causes of differences in regional mortality and of the significant increase in the number of cases between 1980 and 1987. Moreover, the authors...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:The technique of exchange transfusion using a plastic catheter in the umbilical vein developed by Diamond and modified by Allen was instrumental in decreasing the mortality and morbidity in newborn infants with jaundice. Allen et al. demonstrated that the development of kernicterus in infants with erythroblastosis wit...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1990-08-31 00:00:00
abstract：:The material for complete occlusion of an artery is predominantly thrombotic. The longer the occluded segment the worse are the results of PTA since the thrombotic material is not compressible. As long as this thrombotic material is not already organized, it can be lysed by thrombolytic therapy, and thus removed. Rema...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1985-01-18 00:00:00
abstract：:We compared obstetric data from the archives in Graz for 1887 with those of 1987. In 1887, 85% of all deliveries took place in the home or with a midwife--compared with only 0.46% in 1987. Maternal mortality in 1887 was 0.75%; two-thirds of the deaths occurred in the puerperium. Perinatal mortality was 11.0% in 1887 a...
journal_title：Wiener klinische Wochenschrift
pub_type： 历史文章,杂志文章
doi：
更新日期：1989-12-22 00:00:00
abstract：:Since 1997 minimally invasive surgical techniques are used for the treatment of diseases of the adrenals, thyroid, parathyroid and the endocrine pancreas. In contrast to open surgical procedures special radiological examinations are the basis for minimally invasive techniques after biochemical testing. The basis of ex...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:In this meta-analysis the authors evaluated the effectiveness of acupuncture in improving functional communication and language function in post-stroke aphasia (PSA) patients. METHODS:Data sources: MEDLINE, EMBASE, CENTRAL, AMED, SinoMed, CNKI, VIP, and Wanfang databases, ICTRP, ISRCTN, EUCTR, ClinicalTrials...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,meta分析
doi：10.1007/s00508-019-1478-5
更新日期：2019-05-01 00:00:00
abstract：AIM OF THE STUDY:To establish the prevalence of vertebral fractures according to age groups, sex and vertebral level in a sample of a Croatian urban population aged > or =50. We also tried to establish how many people had been diagnosed with osteoporosis by their family physician. PARTICIPANTS AND METHODS:Lateral thor...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00508-004-0292-9
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The practice of inappropriate medication and drug prescription is a major risk factor for adverse drug reactions in geriatric patients and increases the individual, as well as overall, rates of hospital admissions, resulting in increased health care expenditures. A consensus-based list of drugs, generally to...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-011-0061-5
更新日期：2012-03-01 00:00:00
abstract：:Skeletal muscle atrophy is associated with situations of acute and chronical illness, such as sepsis, surgery, trauma and immobility. Additionally, it is a common problem during the physiological process of aging. The myofibrillar proteins myosin and actin, which are essential for muscle contraction, are the major tar...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-007-0817-0
更新日期：2007-01-01 00:00:00
abstract：:Spectrofluorimetry and the pH-sensitive fluorescent dye 2',7'-bis(carboxyethyl)-5(6)carboxyfluorescein (BCECF) was used to measure the intracellular pH (pHi) of suspended human lymphocytes. A linear relationship exists between pHi and the fluorescent spinal-ratio (I490nm/I435nm, emission 526 nm) between pH 6.5 and pH ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-05-26 00:00:00
abstract：:During the last decades a sharp increase in the occurrence of invasive aspergillosis associated with a high mortality has been observed. This fact is mainly due to an increase in the number of immunosuppressed patients. Nosocomial aspergillosis usually is of exogenous origin and often related to building construction ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-05 00:00:00
abstract：:A diagram is presented which enables the continuous recording of biometric values from the earliest possible time right up to the end of pregnancy. It has been tested in practice. The duration of pregnancy and fetal development and growth can be evaluated from the diagram. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-10-12 00:00:00
abstract：:Midodrine, which is used in the treatment of hypotensive circulatory distrubances was investigated with respect to possible effects on carbohydrate and fat metabolism in 5 healthy subjects and 7 patients with disturbed glocuse tolerance. An i.v. glucose tolerance test was carried out on both groups and was repeated a ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-03-04 00:00:00
abstract：:Non invasive ventilation is defined as mechanical ventilation without the use of endotracheal intubation and has been increasingly established within intensive care units during the last decades. Negative pressure ventilation and non invasive positive pressure ventilation have been successfully applied, first in chron...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-15 00:00:00
abstract：:Spinal subdural hematoma (SSDH) following spine surgery is an extremely rare condition, with only three cases being reported in the literature. Unintended durotomy has been associated with SSDH due to alterations of pressures in the dural compartments. The objective of the present report was to report two rare cases o...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0632-3
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:The motor performance of children and adolescents declines. We questioned whether there are differences of motor performance and weight status between preschool children with and without migration background. METHODS:A total of 1,063 4- to 5-year-old children were recruited from 41 kindergartens in Tyrol, A...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-013-0474-4
更新日期：2014-02-01 00:00:00
abstract：:In an autopsy series on 25 newborn infants who died in the perinatal period (19 with and 6 without respiratory distress syndrome [RDS]) the total phospho-lipid, lecithin, and sphingomyelin content was determined in lung homogenates as parameters of the surfactant content. Histologically, the newborn infants with RDS w...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1976-09-17 00:00:00
abstract：BACKGROUND:Primary and secondary myelofibrosis (PMF and SMF) are malignant diseases of hematopoietic stem cell characterized by the neoplastic myeloproliferation and a strong inflammatory milieu. The prognostic nutritional index (PNI) integrates information on albumin and absolute lymphocyte count (ALC) and reflects th...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-018-1318-z
更新日期：2018-02-01 00:00:00
abstract：:40 women with breast cancer were checked by the ultrasound Octoson technique and the results compared with the histological tumour types. We grouped the carcinomas into 3 types: scirrhous, solid or medullary, and the invasive lobular tumour. Our diagnostic ultrasound criteria: internal echoes, as well as contour and b...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1984-10-26 00:00:00
abstract：:The impact of vaccination on the health of the world's people has been considerable. With the possible exception of clean water, no other development has had such a major effect on mortality reduction and population growth. During the last 200 years vaccination has controlled nine major diseases and has led to the era...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-12 00:00:00
abstract：:The tissue polypeptide antigen test (TPA) was carried out in 25 patients with tumours of the maxillofacial region before and after surgery. Further control determination were performed for up to 14 months. A decrease in TPA values was found in only 4 patients after surgery, but a steep rise in TPA values was found wit...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1984-10-12 00:00:00
abstract：:The inscription on Paracelsus' epitaph in the cemetery of Saint Sebastian in Salzburg is critically reviewed with regard to an allusion to Job, Chapter 19. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1989-02-17 00:00:00
abstract：:Intussusception is a rare clinical finding in adults. Most cases occur in the distal small bowel or large intestine. We report the case of a 65-year-old woman with known non-small-cell lung cancer (NSCLC) who presented with acute abdomen and ileus-like symptoms. Abdominal computed tomography suggested ileocecal intuss...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-009-1146-2
更新日期：2009-01-01 00:00:00
abstract：:A report is presented of the course of a case of the myelodysplastic syndrome which transformed after 16 months into Philadelphia chromosome-negative chronic granulocytic leukaemia. Such a transformation into the myeloproliferative syndrome is considered to be a rare event and some views on the mechanism of this metam...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1985-03-29 00:00:00
abstract：OBJECTIVE:To determine the proportion of children with an acute cough and laboratory evidence of Bordetella pertussis (B. pertussis) and B. parapertussis infection. METHODS:A prospective study was done, including children aged 0 months to 16 years who attended the outpatient clinic of the Innsbruck University Hospital...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-06-14 00:00:00
abstract：:Autonomous and uncoordinated proliferation of epithelia leads to various well-known growth patterns such as expansive (cauliflower-like), radiating infiltrative, polycyclic, and roundish-ovoid figures. All attempts to describe such natural growth patterns graphically by Euclidean geometry have failed and remain no mor...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Poliomyelitis, an infectious disease with acute and persistent flaccid paralysis is caused by poliovirus (types 1, 2 or 3), an enterovirus. The infection is asymptomatic in 95% of infected subjects. Most of the paralytic cases occur in adolescents or adults in the course of polio type 1 infection. In the prevaccinatio...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：2001-10-30 00:00:00
abstract：BACKGROUND:Primary warm autoimmune hemolytic anemia (WAIHA) is a rare autoimmune disorder frequently responding to corticosteroid first-line treatment and effective second-line treatment options such as splenectomy or anti-CD20 antibody therapy. Disease management is frequently hampered by a lack of evidence. METHODS:...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0863-y
更新日期：2016-04-01 00:00:00
