Abstract：
BACKGROUND:Primary warm autoimmune hemolytic anemia (WAIHA) is a rare autoimmune disorder frequently responding to corticosteroid first-line treatment and effective second-line treatment options such as splenectomy or anti-CD20 antibody therapy. Disease management is frequently hampered by a lack of evidence. METHODS:We have investigated the probability of sustained treatment-free remission after steroid induction to facilitate clinical decision making regarding timing and necessity of second-line treatments. Response data from 31 patients with primary WAIHA initially treated with steroids were retrospectively analyzed. All patients responded by achieving a hemoglobin of at least 10 mg/dl. RESULTS:After steroid tapering and final withdrawal, 9 of 30 patients remained in unsustained complete remission (CR). The probability of remaining in CR after steroid treatment only was 38.2 % (2 SD 20.6 %) at 15 months. The median remission duration was 100 + months with a range of 12 + to 163 + months. Of note, none of the remaining patients still on steroids achieved CR beyond 15 + months. CONCLUSION:These data indicate that a considerable proportion of patients do not need further treatment and that relapses will not occur after 15 months in CR.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Kulpa J,Skrabs C,Simanek R,Valent P,Panzer S,Lechner K,Sillaber C,Jäger Udoi
10.1007/s00508-015-0863-ysubject
Has Abstractpub_date
2016-04-01 00:00:00pages
234-7issue
7-8eissn
0043-5325issn
1613-7671pii
10.1007/s00508-015-0863-yjournal_volume
128pub_type
杂志文章abstract：:The wearable cardioverter defibrillator (WCD) is a temporary treatment option for patients with potentially reversible risk of sudden cardiac death. This case demonstrates a pitfall during WCD usage in a pacemaker-dependent patient as well as a possible solution allowing continuation of WCD therapy. Bipolar stimulatio...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-017-1290-z
更新日期：2017-12-01 00:00:00
abstract：:Brucellosis remains a problem in many rural areas of Greece. A case report is given of 50 patients with brucellosis treated at the regional hospital of an endemic area. Various forms of fever were observed; a raised temperature was universal. Sweating and joint pains were prominent general symptoms. The most common lo...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-01-21 00:00:00
abstract：:The case is reported of a patient in whom a granulosa cell tumour of the right ovary was removed at the age of 47 years. 14 years later the same type of tumour was found in the left ovary, together with an adenocarcinoma of the body of the uterus. 5 years after removal of these neoplasms splenectomy was carried out on...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-04-29 00:00:00
abstract：:We report our experience with primary angioplasty (PPTCA) in acute myocardial infarction performed without prior thrombolytic therapy. Between January 1991 and April 1993, 44 patients underwent PPTCA. Duration of symptoms was 163 +/ 106 min; age range of patients was 30 to 89 years (mean 60.6 +/- 13.5 years). Twelve p...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Hereditary fructose intolerance (HFI) was diagnosed in a 61 year-old male patient on account of liver dysfunction followed by prolonged shock immediately after the administration of a fructose and lactose infusion postoperatively. The diagnosis of HFI was based on an increased value of fructose, hypoglycaemia, lactic ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1978-03-31 00:00:00
abstract：:The case reports are presented of two siblings with familial thymoma. The thymomas developed at the same age in both siblings. The tumours were removed by thoracotomy and classified histologically as identical thymic squamous cell carcinomas. The brother is still alive and well four years after treatment; the sister d...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1983-06-10 00:00:00
abstract：:Twenty-one patients with an average age of 69 years were subjected to endoscopic sphincterotomy of the papilla of Vater over the past six months. This therapeutic approach was successful and without ensuring complications in 20 of these patients. Hence, endoscopic sphincterotomy can be recommended in the case of elder...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-06-08 00:00:00
abstract：:Due to the markedly increased number of arterial punctures performed during diagnostic angiography and angioplasty procedures for cardiac and peripheral vessel disease, the complication of false aneurysms after arterial puncture has gained increasing significance. The incidence of false aneurysms after puncture report...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Three cases of persistent pulmonary hypertension in newborn infants are reported. One patient developed this syndrome following a normal pregnancy and uneventful delivery, whilst the others had a history of fetal or perinatal distress. Cardiac catheterization showed pulmonary hypertension in two cases in the absence o...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1978-12-08 00:00:00
abstract：BACKGROUND:The obesity epidemic might affect patients with type 1 diabetes (T1DM), historically described as lean and insulin-sensitive subjects. Insulin resistance in T1DM might increase diabetic complications, especially cardiovascular disease. Therefore, the body mass index (BMI) in T1DM patients was analyzed in com...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-018-1434-9
更新日期：2019-02-01 00:00:00
abstract：:Between 1976 and 1987 93 patients with an infrarenal aortic aneurysm underwent surgical correction. In 62 patients the procedure was performed electively, whilst 13 displayed an unstable aneurysm and in 18 cases a ruptured aneurysm was present at operation. During the past 5 years the mortality was lowered to 2% in el...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-01-20 00:00:00
abstract：BACKGROUND:Contamination of surfaces by spores of Clostridium difficile is a major factor influencing the spread of healthcare-associated C. difficile infection. The aim of this study was to test the effect of an automated room disinfection system that provides an aerosol of 7.5 % hydrogen peroxide (H2O2) disinfectant,...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0682-6
更新日期：2015-06-01 00:00:00
abstract：:Acute myocardial infarction induces an inflammatory reaction. We related conventional inflammatory parameters including C-reactive protein, erythrocyte sedimentation rate, white blood cell count and axillary temperature to plasma concentrations of procalcitonin in patients with acute myocardial infarction. In a prospe...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：2002-03-28 00:00:00
abstract：:In order to investigate the association of urinary excretion of sodium and potassium with blood pressure, 72 prepubertal healthy children between 8 and 9 years were investigated in a cross sectional study. We determined anthropometric data, diastolic (DBP), and systolic blood pressure (SBP) and urinary excretion of so...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:The face is affected in more than 50% of patients with extensive burn trauma. Effective treatment is of importance to avoid hypertrophic scarring, functional impairment and social stigmatization. MATERIAL AND METHODS:All patients treated with Acticoat7™ due to superficial and deep partial thickness burns of...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01757-z
更新日期：2020-10-30 00:00:00
abstract：:Modern techniques in brachyradiotherapy using moulds are described for various tumours of the head and neck. The ideal dose distribution can be calculated by the use of computers and practical examples are shown. The radiobiological and also economical advantages of this method of treatment are discussed. ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1980-02-15 00:00:00
abstract：:Ulcerative colitis occurs before the age of 15 years in 20% and before 20 years in 40% of all patients involved. The frequency of this disease in patients at the University Children's Hospital of Munich has clearly risen over the past years. In many patients we found characteristic differences in history, clinical pic...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1986-08-29 00:00:00
abstract：:We report the case of a 60 year-old woman who developed a slowly progressive retrograde diplegia of the lumbo-sacral plexus with mixed sensomotor losses. This occurred with a delay of 6 years after telecobalt irradiation of a pelvic squamous cell carcinoma. Extensive investigations regarding the possibility of tumour ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1981-04-17 00:00:00
abstract：:Metabolic derangements in diabetic coma are the sequelae of insulin deficiency. These defects are aggravated by the actions of insulin counteracting ("diabetogenic") hormones and hypertonic dehydration, which both impair insulin action. Conversely, it has been shown that hypo-osmolar rehydration of a hyperosmolar, sev...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1984-04-27 00:00:00
abstract：BACKGROUND:Down syndrome is the most commonly occurring chromosomal condition with a prevalence of 11.2-10000 life-births in Europe. The most important concern consists of various degrees of intellectual disability and sensory deficits. The overall prevalence of ophthalmologic abnormalities has been reported to be as h...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0750-6
更新日期：2015-08-01 00:00:00
abstract：:Skin and soft tissue infections (SSTIs) are among the most common health problems in travellers returning from tropical and subtropical countries. Importantly, the prevalence of Staphylococcus aureus, the most common pathogen for purulent SSTIs, with specific drug resistance, such as methicillin resistant Staphylococc...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-017-1243-6
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:Inflammatory rheumatic diseases and the applied immunosuppressive treatments can lead to bone marrow depressions and promote hematologic malignancies. Our objective was to explore indications for and results of bone marrow examinations in a large cohort. METHODS:Between 1990 and 2004 146 bone marrow examinat...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-009-1264-x
更新日期：2009-01-01 00:00:00
abstract：:Contrast media induced nephropathy is a common complication, particularly in high risk patients, such as patients with chronic kidney disease (CKD) and diabetes. The majority of studies show an increased in-hospital mortality and an unfavourable long-term prognosis after manifestation of contrast media induced nephrop...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-009-1145-3
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Addressing the growing burden of mental diseases is a public health priority. Nevertheless, many countries lack reliable estimates of the proportion of the population affected, which are crucial for health and social policy planning. This study aimed to collect existing evidence on the prevalence of mental d...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-018-1316-1
更新日期：2018-02-01 00:00:00
abstract：:The established elevated risk of lung cancer in smokers led to the hypothesis that environmental tobacco smoke (ETS) also causes malignancies. The solution of this question is complicated by low exposure levels and dose-response dependence, as well as threshold levels. The differences between the toxins in the main- a...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：:Following the WHO protocol for in-vivo tests in areas with intense transmission of uncomplicated falciparum malaria, a randomized comparison of the invivo efficacy of chloroquine alone, sulfadoxine/pyrimethamine alone, and their combined administration was carried out in the third quarter of 2001 in Kaberamaido Distri...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-01-01 00:00:00
abstract：:Gut ischemia-reperfusion injury is a serious condition in intensive care patients. Activation of immune cells within the huge endothelial surface area of gut microcirculation may initiate a systemic inflammatory response with secondary injury to distant organs. Translocation of bacteria and toxins through a leaky gut ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-30 00:00:00
abstract：:Decision-making is complex in modern medicine and should ideally be based on available data, structured knowledge and proper interpretation in the context of an individual patient. Automated algorithms, also termed artificial intelligence that are able to extract meaningful patterns from data collections and build dec...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-017-1275-y
更新日期：2017-12-01 00:00:00
abstract：:The contribution of Albert Wiedmann (1901 to 1970) towards the development of the Viennese Dermatological School are evaluated. The following main points of interest can be focused out of a large number of scientific papers; investigations in the field of venerology, innervation and nutrition of the skin (concept of t...
journal_title：Wiener klinische Wochenschrift
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1981-12-25 00:00:00
abstract：BACKGROUND:This study aims to answer the question to which extent even very heavy nicotine-dependent smokers can benefit from a 3-week inpatient smoking cessation program. A particular focus lies on analyzing the positive effects, which go above and beyond normally anticipated health benefits. METHODS:This is a descri...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0820-9
更新日期：2015-10-01 00:00:00
