Mitogenic and protective activity associated with a lipopolysaccharide from Coxiella burnetii.

Abstract:

:A purified lipopolysaccharide (LPS) isolated from the rickettsial agent of Q fever, Coxiella burnetii phase 1, possesses some of the in vivo and in vitro biological properties previously only associated with bacterial endotoxins. The Coxiella LPS is mitogenic for guinea pig leukocytes, induces non-specific resistance in mice to virulent Candida albicans, causes dermal Schwartzman reactions, and is positive by the limulus lysate assay.

journal_name

Can J Microbiol

authors

Paquet A Jr,Rael ED,Klassen D,Martinez I,Baca OG

doi

10.1139/m78-259

subject

Has Abstract

pub_date

1978-12-01 00:00:00

pages

1616-8

issue

12

eissn

0008-4166

issn

1480-3275

journal_volume

24

pub_type

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