Preservation of the pulmonary vasoconstrictor response to alveolar hypoxia during the administration of halothane to dogs.

abstract：Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...

journal_title：British journal of anaesthesia

authors： Gouëzel C,Lorne E,Bonnet V,Fradin S,Saplacan V,Gérard JL,Hanouz JL,Fellahi JL,Fischer MO,FHT (French Hemodynamic Team).

更新日期：2017-12-01 00:00:00

abstract：:We have studied the cardiovascular effects of equipotent concentrations of halothane or isoflurane, with or without 50% nitrous oxide in oxygen, in 80 patients, aged 60 yr or more, during 20 min of stable equipotent anaesthesia. Non-invasive measurement techniques were used, with suprasternal Doppler ultrasonography f...

journal_title：British journal of anaesthesia

authors： McKinney MS,Fee JP

更新日期：1998-02-01 00:00:00

abstract：:Ropivacaine is considered safer than bupivacaine, on the basis of experimental and human data that indicate a lower systemic toxicity. Here we report the occurrence of a single seizure after i.v. administration of ropivacaine 120 mg intended for extradural block in a patient having postpartum, tubal ligation. The only...

journal_title：British journal of anaesthesia

authors： Abouleish EI,Elias M,Nelson C

更新日期：1998-06-01 00:00:00

abstract：:A combination of exogenous surfactant and partial liquid ventilation (PLV) with perfluorocarbons should enhance gas exchange, improve respiratory mechanics and reduce tissue damage of the lung in acute lung injury (ALI). We used a small dose of exogenous surfactant with and without PLV in an experimental model of ALI ...

journal_title：British journal of anaesthesia

authors： Wolf S,Lohbrunner H,Busch T,Sterner-Kock A,Deja M,Sarrafzadeh A,Neumann U,Kaisers U

更新日期：2001-10-01 00:00:00

abstract：:In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m., "high-level" or "low-level" extradural morphine. Thirty-five per cent in the i.m. group, 33% in the high-level group and 50% in the low-level group suffered urinary...

journal_title：British journal of anaesthesia

authors： Petersen TK,Husted SE,Rybro L,Schurizek BA,Wernberg M

更新日期：1982-11-01 00:00:00

abstract：:The activity of the enzyme methionine synthase in fetal and maternal liver was investigated before and after exposure to nitrous oxide. Timed-pregnant rats on day 19 of gestation were exposed to either 10% or 50% nitrous oxide for various times up to 240 min. After exposure, fetal and maternal livers were removed and ...

journal_title：British journal of anaesthesia

authors： Baden JM,Serra M,Mazze RI

更新日期：1984-05-01 00:00:00

abstract：:We have studied the effects of flow and dobutamine on systemic haemodynamic variables, oxygen delivery (DO2) and oxygen consumption (VO2) in 20 patients during cardiopulmonary bypass (CPB) with mild hypothermia (34 degrees C). In a subgroup of seven patients, we also studied the effects on gastric microcirculatory blo...

journal_title：British journal of anaesthesia

authors： Karzai W,Lötte A,Günnicker M,Vorgrimler-Karzai UM,Priebe HJ

更新日期：1996-01-01 00:00:00

abstract：:We have investigated the effect of four doses of remifentanil on the incidence of respiratory depression and somatic response at incision. Remifentanil was administered as a loading dose of 0.125, 0.25, 0.375 or 0.5 microgram kg-1 and at a maintenance infusion rate of 0.025, 0.05, 0.075 or 0.1 microgram kg-1 min-1, re...

journal_title：British journal of anaesthesia

authors： Peacock JE,Luntley JB,O'Connor B,Reilly CS,Ogg TW,Watson BJ,Shaikh S

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Miller laryngoscope blades are preferred for laryngoscopy in infants and children <2 yr of age. Despite their long history, the laryngeal view with the Miller blade size 1 has never been compared with that with the Macintosh (MAC) blade in children. This prospective, single-blinded, randomized study was desi...

journal_title：British journal of anaesthesia

authors： Passi Y,Sathyamoorthy M,Lerman J,Heard C,Marino M

更新日期：2014-11-01 00:00:00

abstract：:Diltiazem inhibited and antagonized the abnormal contractures induced by halothane, caffeine and potassium chloride in isolated skeletal muscle from pigs susceptible to malignant hyperpyrexia (MHS). Contractile responses to caffeine and electrical stimulation also were suppressed by diltiazem in control tissue. Simila...

journal_title：British journal of anaesthesia

authors： Foster PS,Denborough MA

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to investigate sublingual microvascular blood flow and microcirculatory haemoglobin oxygen saturation (Smc(O(2))) during cardiopulmonary bypass (CPB) using constant systemic blood flow but different perfusion pressures achieved by phenylephrine administration. METHODS:...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder WR,Hengl C,Pajk W,Schwarz B,Margreiter J,Ulmer H,Engl J,Knotzer H

更新日期：2009-04-01 00:00:00

abstract：:Blood concentrations of nitrous oxide were measured in anaesthetists, surgeons and theatre nurses. Comparison of anaesthetists and surgeons working in the same theatre showed that in ENT surgeons concentrations were greater (P < 0.01), while in general surgeons they were smaller (P < 0.003). Blood concentrations of ni...

journal_title：British journal of anaesthesia

authors： Krapez JR,Saloojee Y,Hinds CJ,Hackett GH,Cole PV

更新日期：1980-11-01 00:00:00

abstract：:We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following a...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Toyooka H,Amaha K

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Parecoxib, a cyclo oxygenase-2 inhibiting non-steroidal anti-inflammatory drug, has been widely used for postoperative analgesia. Our aim was to quantify the benefit of a single dose after coronary artery bypass grafting. METHODS:The investigation was carried out as a randomized double blind placebo control...

journal_title：British journal of anaesthesia

authors： Khalil MW,Chaterjee A,Macbryde G,Sarkar PK,Marks RR

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The effect of anaesthesia on postoperative outcome is unclear. Cardioprotective properties of volatile anaesthetics have been demonstrated experimentally and in haemodynamically stable patients undergoing coronary artery bypass grafting. Their effects in patients undergoing high-risk cardiac surgery have not...

journal_title：British journal of anaesthesia

authors： Landoni G,Guarracino F,Cariello C,Franco A,Baldassarri R,Borghi G,Covello RD,Gerli C,Crivellari M,Zangrillo A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Handover of anaesthesia patient care during surgery is common; however, its association with patient outcome is unclear. This systematic review aimed to assess the impact of anaesthesia handover during surgery on patient outcome. METHODS:All prospective and retrospective clinical studies specifically invest...

journal_title：British journal of anaesthesia

authors： Boet S,Djokhdem H,Leir SA,Théberge I,Mansour F,Etherington N

更新日期：2020-10-01 00:00:00

abstract：:The analgesic effects of buprenorphine 2 microgram/kg--1 and 8 microgram. kg--1 were compared with those of pethidine 1 mg. kg--1 and pentazocine 0.6 mg.kg--1 in 172 patients recovering from surgery. The drugs were given by i.m. injection in the period immediately after operation and the quality of pain relief was ass...

journal_title：British journal of anaesthesia

authors： Hovell BC

更新日期：1977-09-01 00:00:00

abstract：:Sepsis is a constellation of clinical signs and symptoms resulting from excessive systemic host inflammatory response to infection. This inflammatory response is largely mediated by cytokines, which are released into the systemic circulation. Plasma concentrations of specific cytokines, TNF alpha, IL-1 beta, IL-6 and ...

journal_title：British journal of anaesthesia

authors： Blackwell TS,Christman JW

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Aortocaval compression (ACC) can result in haemodynamic disturbances and uteroplacental hypoperfusion in parturients. Its detection is difficult because in most patients, sympathetic compensation results in no signs or symptoms. However, profound hypotension may develop after sympathectomy during regional an...

journal_title：British journal of anaesthesia

authors： Lee SW,Khaw KS,Ngan Kee WD,Leung TY,Critchley LA

更新日期：2012-12-01 00:00:00

abstract：:When using endobronchial anaesthesia for the management of transthoracic endoscopic sympathectomy (TES), excessive insufflation of carbon dioxide into the pleural space may cause haemodynamic instability, hypoxaemia and tension pneumothorax. We prospectively studied an alternative technique using a tracheal tube, i.v....

journal_title：British journal of anaesthesia

authors： Olsfanger D,Jedeikin R,Fredman B,Shachor D

更新日期：1995-02-01 00:00:00

abstract：:We have investigated, in six healthy male volunteers, the effect of high thoracic extradural anaesthesia on the ventilatory pattern and hypercapnic ventilatory response. Ventilatory variables were determined using a respiratory inductive plethysmograph. Duration of inspiration, rib cage excursion and its contribution ...

journal_title：British journal of anaesthesia

authors： Kochi T,Sako S,Nishino T,Mizuguchi T

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:The properties of methadone suggest a potential advantage for epidural over i.v. administration for pain relief, but little supportive evidence exists. METHODS:To investigate the pharmacokinetic and the pharmacodynamic properties of epidural and i.v. methadone, four doses of methadone (0.1, 0.25, 0.5, and 0...

journal_title：British journal of anaesthesia

authors： Haroutiunian S,Kagan L,Yifrach-Damari I,Davidson E,Ratz Y,Hoffman A

更新日期：2014-01-01 00:00:00

abstract：:Successful tracheal intubation with the flexible fibreoptic bronchoscope requires a certain amount of skill which is acquired by practice. It has been suggested that the new Bullard laryngoscope may be mastered more easily. To determine if learning was superior with a flexible fibreoptic or the Bullard device, the eas...

journal_title：British journal of anaesthesia

authors： Dyson A,Harris J,Bhatia K

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The use of lipid emulsions to reduce cardiac toxicity of local anaesthetics (LAs) has shown success in experimental studies and some clinical cases, and thus has been implemented in clinical practice. However, lipid treatment is usually given after the occurrence of neurological or cardiovascular symptoms of...

journal_title：British journal of anaesthesia

authors： Aumeier C,Kasdorf B,Gruber M,Busse H,Wiese CH,Zink W,Graf BM,Zausig YA

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:This study compared the efficacy of topical anaesthesia with levobupivacaine 0.75% vs lidocaine 2% during cataract surgery by phacoemulsification. METHODS:A prospective, randomized, double-blind study comparing two agents for topical anaesthesia in cataract surgery. Two hundred and forty-six consecutive pat...

journal_title：British journal of anaesthesia

authors： Fernández SA,Dios E,Diz JC

更新日期：2009-02-01 00:00:00

abstract：:Muscle fasciculations and pain following the administration of suxamethonium were assessed in a group of patients who performed a series of stretch exercises approximately 1 h before operation. Comparison was made with a group who received suxamethonium but no pretreatment. Fasciculations were significantly reduced in...

journal_title：British journal of anaesthesia

authors： Magee DA,Robinson RJ

更新日期：1987-05-01 00:00:00

abstract：:A patient with Ebstein's anomaly undergoing anaesthesia for the operation of hysterectomy is reported. The considerations relating to the risk of an increased right-to-left intracardiac shunt are discussed. The patient was anaesthetized successfully with a combination of nitrous oxide, droperidol and fentanyl. ...

journal_title：British journal of anaesthesia

authors： Bengtsson IM,Magno R,Wickström I

更新日期：1977-05-01 00:00:00

abstract：:In a randomized, double-blind study, we have examined the stereoselective disposition and pharmacodynamic characteristics of ketamine in surgical patients after i.v. administration of S(+)-ketamine 1 mg/kg body weight (25 patients) or racemic ketamine 2 mg/kg body weight (25 patients). S(+)-Ketamine was not inverted t...

journal_title：British journal of anaesthesia

authors： Geisslinger G,Hering W,Thomann P,Knoll R,Kamp HD,Brune K

更新日期：1993-06-01 00:00:00

abstract：:Forty patients (age range 60-79 yr) undergoing transurethral surgery were allocated randomly to receive 0.5% plain bupivacaine 4 ml at the L2-3 (n = 20) or L4-5 (n = 20) space. The solution was injected over 30 s with the patient in the sitting position. The patient was kept sitting for 2 min, then placed supine and, ...

journal_title：British journal of anaesthesia

authors： Olsen KH,Nielsen TH,Kristoffersen E,Husegaard HC,Wernberg M,Dørup J

更新日期：1990-02-01 00:00:00

abstract：:Visceromotor responses and vasopressin release before and after colonic visceral distension were compared between male (n=5 (n=4 for vasopressin)) and female rats and between females during the oestrous cycle (proestrus n=6, oestrus n=5, metestrus n=5, diestrus n=6) at a controlled depth of anaesthesia. Pre-stimulatio...

journal_title：British journal of anaesthesia

authors： Holdcroft A,Sapsed-Byrne S,Ma D,Hammal D,Forsling ML

更新日期：2000-12-01 00:00:00