Inhibition of fetal methionine synthase by nitrous oxide.

abstract：:Twenty consecutive patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) were allocated at random to group 1 (n = 10, high inspired oxygen fraction (FIO2) after CPB), or group 2 (n = 10, moderate FIO2 after CPB). The effects of each FIO2 on arterial and mixed venous concentrations of endothelin-1 (ET-1...

journal_title：British journal of anaesthesia

authors： Reber A,Budmiger B,Wenk M,Haefeli WE,Wolff T,Bein T,Skarvan K

更新日期：2000-05-01 00:00:00

abstract：:The effects of diazepam, which acts at GABAA receptors to enhance the effects of GABA, and ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, on local rates of cerebral glucose utilization (ICMRglc) were examined in unrestrained rats. Four groups were studied: vehicle-injected controls; and ketamine...

journal_title：British journal of anaesthesia

authors： Eintrei C,Sokoloff L,Smith CB

更新日期：1999-04-01 00:00:00

abstract：:Thirteen of 31 Belgian Landrace pigs developed malignant hyperthermia (MH) after breathing halothane. A short period of exercise 1 h before the administration of the triggering agent increased the incidence of the syndrome to 100% in eight similar pigs. Clinical symptoms were more marked and developed more rapidly in ...

journal_title：British journal of anaesthesia

authors： van den Hende C,Lister D,Muylle E,Ooms L,Oyaert W

更新日期：1976-09-01 00:00:00

abstract：:Placental transfer of 14C-dimethyltubocurarine (14C-dmtc) was studied during Caesarean section. Liquid scintillation counting was used for determination of 14C activity from the maternal and foetal blood samples. Paper chromatography was used to confirm the stability of 14C-dmtc. In all cases 14C-dmtc was able to cros...

journal_title：British journal of anaesthesia

authors： Kivalo I,Saarikoski S

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Evidence-based international expert consensus regarding anaesthetic practice in hip/knee arthroplasty surgery is needed for improved healthcare outcomes. METHODS:The International Consensus on Anaesthesia-Related Outcomes after Surgery group (ICAROS) systematic review, including randomised controlled and ob...

journal_title：British journal of anaesthesia

authors： Memtsoudis SG,Cozowicz C,Bekeris J,Bekere D,Liu J,Soffin EM,Mariano ER,Johnson RL,Hargett MJ,Lee BH,Wendel P,Brouillette M,Go G,Kim SJ,Baaklini L,Wetmore D,Hong G,Goto R,Jivanelli B,Argyra E,Barrington MJ,Borgea

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:In 2016, the World Health Organization (WHO) strongly recommended the use of a high fraction of inspired oxygen (FiO2) in adult patients undergoing general anaesthesia to reduce the risk of surgical site infection (SSI). Since then, further trials have been published, trials included previously have come und...

journal_title：British journal of anaesthesia

authors： de Jonge S,Egger M,Latif A,Loke YK,Berenholtz S,Boermeester M,Allegranzi B,Solomkin J

更新日期：2019-03-01 00:00:00

abstract：:A method for the assessment and management of factors both causing and maintaining a primary metabolic alkalosis is presented. During a 2-year period 65 patients with metabolic alkalosis were treated with saline and potassium chloride infusions. In four patients the alkalosis was refractory and required additional the...

journal_title：British journal of anaesthesia

authors： Worthley LI

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:There is limited clinical experience with xenon in a large number of patients. We present intra- and postoperative haemodynamic and recovery data comparing xenon and total intravenous anaesthesia with propofol. METHODS:A total of 160 patients aged 18-60 years (ASA I and II) undergoing elective surgery took ...

journal_title：British journal of anaesthesia

authors： Coburn M,Kunitz O,Baumert JH,Hecker K,Haaf S,Zühlsdorff A,Beeker T,Rossaint R

更新日期：2005-02-01 00:00:00

abstract：:Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of a...

journal_title：British journal of anaesthesia

authors： Dutton RP

更新日期：2012-12-01 00:00:00

abstract：:For 6 months after renal transplant serum cholinesterase concentrations were measured in 10 patients. The value decreased in the first 15 days after operation, but was normal thereafter. Liver function tests were normal throughout the study; the cholinesterase changes were independent of immunosuppressive therapy. ...

journal_title：British journal of anaesthesia

authors： Ryan DW

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Assessments of labour pain focus on pain intensity, not on duration. We aimed to assess the importance labouring women apply to pain intensity and duration before labour and post-delivery. METHODS:Forty healthy women scheduled for labour induction were enrolled in this institutional review board-approved, p...

journal_title：British journal of anaesthesia

authors： Carvalho B,Hilton G,Wen L,Weiniger CF

更新日期：2014-09-01 00:00:00

abstract：:The analgesic effect of subanaesthetic concentrations of ether, trichloroethylene, methoxyflurane and halothane has been investigated previously using either clinical assessment or pain threshold measurements, but with conflicting results. The purpose of the present study was to evaluate the analgesic effect of isoflu...

journal_title：British journal of anaesthesia

authors： Petersen-Felix S,Arendt-Nielsen L,Bak P,Roth D,Fischer M,Bjerring P,Zbinden AM

更新日期：1995-07-01 00:00:00

abstract：:We have investigated the effects of propofol on beat-to-beat fluctuations in heart rate, arterial pressure (continuous arterial tonometry) and infrared finger plethysmography in 10 healthy male patients undergoing elective surgery. Administration of Diprivan (propofol 10 mg ml-1) 0.2 ml kg-1, followed by an infusion o...

journal_title：British journal of anaesthesia

authors： Robinson BJ,Buyck HC,Galletly DC

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:This study focuses on a recently developed robotic nerve block system and its impact on learning regional anaesthesia skills. We compared success rates, learning curves, performance times, and inter-subject performance variability of robot-assisted vs manual ultrasound (US)-guided nerve block needle guidance...

journal_title：British journal of anaesthesia

authors： Morse J,Terrasini N,Wehbe M,Philippona C,Zaouter C,Cyr S,Hemmerling TM

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. MET...

journal_title：British journal of anaesthesia

authors： Winkler BE,Schuetz W,Froeba G,Muth CM

更新日期：2012-12-01 00:00:00

abstract：:A retrospective study of serious non-fatal complications of extradural block in obstetric practice was carried out using a postal questionnaire. Two hundred and three obstetric units in the United Kingdom (responsible for 2,580,000 deliveries from 1982 to 1986 inclusive) responded. A total of 505,000 extradural blocks...

journal_title：British journal of anaesthesia

authors： Scott DB,Hibbard BM

更新日期：1990-05-01 00:00:00

abstract：:Single dose-response curves were determined for suxamethonium in neonates, infants and children during thiopentone-fentanyl-nitrous oxide anaesthesia. During onset of neuromuscular block, suxamethonium produced an increase in muscle tone which was greatest in neonates and infants. The dose-response curves for the thre...

journal_title：British journal of anaesthesia

authors： Meakin G,McKiernan EP,Morris P,Baker RD

更新日期：1989-06-01 00:00:00

abstract：:We have compared the efficacy of patient-controlled interscalene analgesia (PCIA) using ropivacaine with patient-controlled analgesia (PCA) using nicomorphine in 60 patients (n = 30 in each group), in a prospective, randomized study. In both groups, all patients received interscalene block with 0.75% ropivacaine befor...

journal_title：British journal of anaesthesia

authors： Borgeat A,Tewes E,Biasca N,Gerber C

更新日期：1998-10-01 00:00:00

abstract：:Acute perioperative changes in arterial pressure occur frequently, particularly in patients with cardiovascular disease or those receiving vasoactive medications, or in relation to certain cardiovascular surgical procedures. Both hypo- and hypertension are common in patients undergoing carotid surgery because of uniqu...

journal_title：British journal of anaesthesia

authors： Stoneham MD,Thompson JP

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:A pulmonary hypertensive crisis (PHC) can be a life-threatening condition. We established a PHC model by exposing rats with monocrotaline (MCT)-induced pulmonary hypertension to acute hypoxia, and investigated the effects of vasopressin, phenylephrine, and norepinephrine on the PHC. METHODS:Four weeks after...

journal_title：British journal of anaesthesia

authors： Sugawara Y,Mizuno Y,Oku S,Goto T

更新日期：2019-04-01 00:00:00

abstract：:Fast inactivation of sodium channel function is modified by anaesthetics. Its quantitative contribution to the overall anaesthetic effect is assessed by removing the fast inactivation mechanism enzymatically. Sodium channels from human brain cortex were incorporated into planar lipid bilayers. After incorporation, cha...

journal_title：British journal of anaesthesia

authors： Wartenberg HC,Urban BW,Duch DS

更新日期：1999-01-01 00:00:00

abstract：:Critical narrowing of the dependent airways was examined in anaesthetized dogs with closed chests. Two techniques were used, (a) "closing" volume (CV), measured from the expired nitrogen plateau and (b) tantalum bronchography, to measure the calibre of airways of 3-8 mm diameter in the upper (UZ), middle (MZ) and lowe...

journal_title：British journal of anaesthesia

authors： Jones JG,Graf PD,Lemen R

更新日期：1978-08-01 00:00:00

abstract：:Atropine and glycopyrrolate were compared in a mixture with neostigmine for reversal of neuromuscular blockade in patients undergoing open heart surgery. In patients not receiving beta-blocking drugs, glycopyrrolate was shown to possess advantages over atropine in terms of a lower initial increase in heart rate, bette...

journal_title：British journal of anaesthesia

authors： Salem MG,Richardson JC,Meadows GA,Lamplugh G,Lai KM

更新日期：1985-02-01 00:00:00

abstract：:Cardioventilatory coupling (CVC) is the temporal coherence of respiratory and cardiac rhythms. We have suggested that this coherence is the result of triggering of inspiratory onset by a preceding cardiovascular afferent. One implication of this triggering hypothesis is that coupling should only exist under conditions...

journal_title：British journal of anaesthesia

authors： Larsen PD,Trent EL,Galletly DC

更新日期：1999-04-01 00:00:00

abstract：:We report the anaesthetic management of a male neonate with congenital cyst adenoid malformation (CCAM) of the lung who underwent thoracotomy for resection of CCAM 24 h after birth and again at 24 days. The initial operation involved a 10-day admission to a paediatric intensive care unit (PICU) requiring ventilation, ...

journal_title：British journal of anaesthesia

authors： Guruswamy V,Roberts S,Arnold P,Potter F

更新日期：2005-08-01 00:00:00

abstract：:In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m., "high-level" or "low-level" extradural morphine. Thirty-five per cent in the i.m. group, 33% in the high-level group and 50% in the low-level group suffered urinary...

journal_title：British journal of anaesthesia

authors： Petersen TK,Husted SE,Rybro L,Schurizek BA,Wernberg M

更新日期：1982-11-01 00:00:00

abstract：:The Myotest is a new nerve stimulator which can give train-of-four, single twitch (1 and 10 s) and tetanic stimuli. Power is supplied by standard batteries, which allow 200 h effective use. The impulse is unipolar constant current, and the amplitude can be adjusted between 0 and 40 mA. These factors, plus the electron...

journal_title：British journal of anaesthesia

authors： Viby-Mogensen J,Hansen PH,Jørgensen BC,Ording H,Kann T,Fries B

更新日期：1980-05-01 00:00:00

abstract：:Although rare, spinal haematoma and abscess after central neuraxial blocks may cause severe permanent neurological injury. Optimal treatment and outcome remain unclear. In order to identify possible predisposing patient characteristics and describe the ensuing clinical course, we searched Medline, Embase, and the Coch...

journal_title：British journal of anaesthesia

authors： Bos EME,Haumann J,de Quelerij M,Vandertop WP,Kalkman CJ,Hollmann MW,Lirk P

更新日期：2018-04-01 00:00:00

abstract：:A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...

journal_title：British journal of anaesthesia

authors： Fry EN

更新日期：1975-06-01 00:00:00

abstract：:The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome. The results, which are expressed in accordance with the criteria of the European MH Group, defined five of the subjects as MHN and one patient as MHE. It is concluded tha...

journal_title：British journal of anaesthesia

authors： Krivosic-Horber R,Adnet P,Guevart E,Theunynck D,Lestavel P

更新日期：1987-12-01 00:00:00