Abstract:
:Motion of the posterior aortic root on echocardiography is related to left atrial volume changes. Early diastolic posterior motion of the aortic root reflects both LA emptying and filling and has been measured as the atrial emptying index. To study late diastolic motion of the aortic root, we measured the slope of posterior motion of the aortic root after left atrial systole (following the P wave of the ECG) in 25 subjects without heart disease (Group 1), in 15 patients with left ventricular hypertrophy due to pressure overload (Group 3) with mitral stenosis. The aortic root slope measured (mean +/- SEM) 58.0 +/- 1.9 mm./sec. in Group 1, 50.6 +/- 4.5 mm./sec. in Group 2 (NS vs 1) and 28.8 +/- 4.5 mm./sec. in Group 3, (p < 0.01 vs 1 or 2). In 16 patients (four in Group 1 and 12 in Group 2) studied at catheterization, an inverse correlation ( r = -0.74, p < 0.01) was found between the aortic root slope (over a range of 30 to 73 mm./sec.) and left ventricular late diastolic chamber stiffness measured with simultaneous left ventricular echo and high-fidelity pressure recordings. No correlation was found between this slope and either left atrial size, total aortic root excursion, left ventricular pressure pre "A" wave, height of the A wave, end-diastolic pressure, or the atrial contribution to left ventricular filling. Therefore, the aortic root slope in late diastole is decreased in mitral stenosis and in the absence of mitral stenosis, it appears to be related to late diastolic properties of the left ventricle.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Ambrose JA,Martinez EE,Meller J,Gorlin R,Pichard AD,Herman MV,Teichlolz LEdoi
10.1016/0002-8703(80)90654-7subject
Has Abstractpub_date
1980-10-01 00:00:00pages
433-40issue
4eissn
0002-8703issn
1097-6744pii
0002-8703(80)90654-7journal_volume
100pub_type
杂志文章abstract:BACKGROUND:Platelet inhibition is critical in reducing both short- and long-term atherothrombotic risks after acute myocardial infarction (MI), especially among patients managed with percutaneous coronary intervention (PCI). Currently available antiplatelet medications, including adenosine diphosphate (ADP) receptor in...
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更新日期:2007-06-01 00:00:00
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更新日期:2013-10-01 00:00:00
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更新日期:1991-03-01 00:00:00
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更新日期:2019-05-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1988-07-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-05-01 00:00:00
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更新日期:2013-03-01 00:00:00
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更新日期:2013-12-01 00:00:00
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更新日期:1989-11-01 00:00:00
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更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:1987-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2020-04-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.109946
更新日期:2001-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2003-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1992-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:1986-11-01 00:00:00