Abstract:
:Partially purified hemoglobin A2 has been examined for the existence of glycosylated components by isoelectric focusing and by acid agar gel electrophoresis. Bands analogous to the glycohemoglobin derivatives of hemoglobin A, hemoglobin-A1.a.b.c, were readily detected. Evidence that these minor bands are in fact glycohemoglobins was obtained by showing that 14C-glucose bound to hemoglobin A2 moved with these minor bands. The amounts of glycohemoglobin derivatives of hemoglobin A2 were increased in the blood of diabetic patients.
journal_name
Bloodjournal_title
Bloodauthors
Tegos C,Beutler Esubject
Has Abstractpub_date
1980-09-01 00:00:00pages
571-2issue
3eissn
0006-4971issn
1528-0020journal_volume
56pub_type
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