Production and characterization of monoclonal antibodies against bovine luteinizing hormone.

abstract：:Investigating the expression of lipoteichoic acid (LTA) from Listeria monocytogenes, we found two distinct structural variants of LTA (LTA1 and LTA2) using NMR and MS technology. While both LTA consisted of a poly-glycerophosphate backbone (differing in length) bound via a disaccharide to a diacyl-glycerol moiety, one...

journal_title：Immunobiology

authors： Dehus O,Pfitzenmaier M,Stuebs G,Fischer N,Schwaeble W,Morath S,Hartung T,Geyer A,Hermann C

更新日期：2011-01-01 00:00:00

abstract：:Ribosomal 30S and 50S subunits as well as total proteins from the large subunit of E. coli ribosomes were found to be potent mitogens for both human adult and cord blood lymphocytes. On the other hand, the RNA fraction of the 50S subunit had only a weak stimulatory capacity suggesting that the protein moiety contains ...

journal_title：Immunobiology

authors： Sieber G,Rühl H

更新日期：1980-01-01 00:00:00

abstract：:The macrophage population of the gastro-intestinal tract of the rat was studied by using a set of three monoclonal antibodies (ED1, ED2 and ED3) directed against rat macrophages, an anti-Ia monoclonal antibody and by performing an acid phosphatase reaction. The lamina propria of the whole gastro-intestinal tract compr...

journal_title：Immunobiology

authors： Sminia T,Jeurissen SH

更新日期：1986-08-01 00:00:00

abstract：:We hypothesized that anti-citrullinated protein antibodies (ACPAs) could affect the expression of miRNAs in monocytes and contribute to the inflammatory responses in rheumatoid arthritis (RA). The expression profiles of 270 human miRNAs, co-cultured with ACPAs or human immunoglobulin G (IgG), were analyzed using real-...

journal_title：Immunobiology

authors： Lai NS,Yu HC,Yu CL,Koo M,Huang HB,Lu MC

更新日期：2015-12-01 00:00:00

abstract：:Polyclonally activated lymphoblasts, transferred to syngeneic recipient mice, elicited a host T-cell-mediated "response" in vivo. These T cells, which "responded" in vivo to syngeneic lymphoblasts (i.e. in vivo primed "responder" T-cell population), acquired the capacity to "stimulate" a "response" of syngeneic T cell...

journal_title：Immunobiology

authors： Reimann J,Diamantstein T

更新日期：1980-12-01 00:00:00

abstract：:IFN-γ produced during viral infections activates the IFN-γ receptor (IFNGR) complex for STAT1 transcriptional activity leading to expression of Interferon Regulatory Factors (IRF). Simultaneous activation of TBK/IKKε via TLR3 during viral infections activates the transcription factor IRF3. Together these transcription...

journal_title：Immunobiology

authors： Guinn ZP,Petro TM

更新日期：2019-07-01 00:00:00

abstract：:The aim of this study was to evaluate some immunological patterns involved in natural and acquired resistance against MHV3 using the original model of genetically modified lines of mice selected for high (HIII) and low (LIII) antibody responsiveness. As previously shown, a lower pre-existing anti-MHV antibody level wa...

journal_title：Immunobiology

authors： Vassão RC,Consales CA,Sant'Anna OA,Pereira CA

更新日期：2003-01-01 00:00:00

abstract：:Flavonoids are ubiquitous compounds present in plant extracts. They represent a major active component of the plant extract and are often known for their anti-inflammatory and anti-tumor effects. Previously, we demonstrated that Ligaria cuneifolia (R et P) Tiegh. (Loranthaceae) extracts inhibit proliferation of murine...

journal_title：Immunobiology

authors： Cerdá Zolezzi P,Fernández T,Aulicino P,Cavaliere V,Greczanik S,Caldas Lopes E,Wagner M,Ricco R,Gurni A,Hajos S,Alvarez E

更新日期：2005-01-01 00:00:00

abstract：:In the last decade new glucocorticoid (GC)-signalling mechanisms have emerged. The evolving field of non-genomic GC actions was precipitated from two major directions: (i) some rapid/acute clinical GC applications could not be explained based on the relatively slowly appearing genomic GC action and (ii) accumulating e...

journal_title：Immunobiology

authors： Boldizsar F,Talaber G,Szabo M,Bartis D,Palinkas L,Nemeth P,Berki T

更新日期：2010-07-01 00:00:00

abstract：:Anti-anaemic drug ferric-sorbitol citrate showed immunomodulatory effects, activating NF-kappaB in peritoneal macrophages, which consequently secrete tumour necrosis factor-alpha (TNF-alpha). TNF-alpha activates NF-kappaB in spleen cells. The aim of this study was to investigate the effect of iron polyisomaltosate, an...

journal_title：Immunobiology

authors： Poljak-Blazi M,Jaganjac M,Mustapic M,Pivac N,Muck-Seler D

更新日期：2009-01-01 00:00:00

abstract：:Lymphocytes from spleen, thymus and lymph nodes from individual young adult (3--4 months) and aged (26--30 months) NMRI mice were stimulated with the mitogens Con A, PHA and LPS. 24 hours later, the number of cell with increased RNA-content (G1 cells) was determined by cytofluorometry. In parallel the 3H-thymidine inc...

journal_title：Immunobiology

authors： Joncourt F,Bettens F,Kristensen F,de Weck AL

更新日期：1981-06-01 00:00:00

abstract：:The Hepatitis B virus (HBV) e antigen (HBeAg) is a secretory, non-structural protein, and associated with persistent infection of HBV. Previous studies indicate that HBeAg is able to regulate T cell-mediated responses, however, the interaction between HBeAg and the innate immune system is poorly understood. In this st...

journal_title：Immunobiology

authors： Leu CM,Lu YC,Peng WL,Chu HT,Hu CP

更新日期：2014-11-01 00:00:00

abstract：:Sialoadhesin (Sn) is a surface receptor expressed on resident macrophages with the ability to bind with sialic acids. During inflammation, an upregulation of Sn is observed. Upon binding of monoclonal antibodies to Sn, the receptor becomes internalized and this has been observed in multiple species. The latter charact...

journal_title：Immunobiology

authors： De Schryver M,Leemans A,Pintelon I,Cappoen D,Maes L,Caljon G,Cos P,Delputte PL

更新日期：2017-06-01 00:00:00

abstract：:CD147 is a broadly expressed cell surface molecule of the immunoglobulin superfamily whose expression is up-regulated upon T cell activation. Engagement of CD147 by CD147 monoclonal antibodies (mAbs) has been shown to induce homotypic aggregation of U937 cells. To study intracellular signal transduction induced by the...

journal_title：Immunobiology

authors： Khunkeawla P,Moonsom S,Staffler G,Kongtawelert P,Kasinrerk W

更新日期：2001-05-01 00:00:00

abstract：:Activated macrophages have various characteristics in common with exudate and resident macrophages, but the ability to inhibit intracellular proliferation of the protozoa Toxoplasma gondii, the expression of Ia antigen and the capacity to produce H2O2 varies among these cells. Assessment of these features of macrophag...

journal_title：Immunobiology

authors： Nibbering PH,Langermans JA,van de Gevel JS,van der Hulst MB,van Furth R

更新日期：1991-12-01 00:00:00

abstract：:Vitamin D [25(OH)D3] deficiency has been associated with asthma as in many inflammatory and autoimmune pathologies; however, there is still a lack of data about the effects of administration of vitamin D in immune regulation in young asthmatic patients. In this study, we investigated its inhibitory effect on the immun...

journal_title：Immunobiology

authors： Hamzaoui A,Berraïes A,Hamdi B,Kaabachi W,Ammar J,Hamzaoui K

更新日期：2014-11-01 00:00:00

abstract：:The homotypic cell aggregation of leukocytes is an unique adhesive event which is caused by cellular activation. Anti-CD44 monoclonal antibody (mAb) induces homotypic cell aggregation of hematopoietic cell lines expressing CD44, but the mechanism of homotypic cell aggregation is poorly understood. We used four mAbs ag...

journal_title：Immunobiology

authors： Cao L,Yoshino T,Nishiuchi R,Yamadori I,Akagi T

更新日期：1995-06-01 00:00:00

abstract：:The ability of RPMI 1640 enriched with FCS or AATSZ (L-alanine, BSA, human transferrin, zinc chloride, and sodium selenite) to support mitogen-induced activation (G0-G1 shift) and proliferation (G1-S shift) of thymocytes has been investigated. The two culture media were found to be equally supportive. In terms of viab...

journal_title：Immunobiology

authors： Kristensen F,Walker C,Müller J,de Weck AL

更新日期：1982-05-01 00:00:00

abstract：:The recent purification and cloning of T cell-derived growth factors, should lead to rapid progress in delineating their role in the generation of accessory cells and the regulation of their function. The techniques that have allowed detailed in vitro studies of the T-dependent mast cells, should be generally applicab...

journal_title：Immunobiology

authors： Schrader JW,Clark-Lewis I,Wong GH

更新日期：1984-12-01 00:00:00

abstract：:Mono Mac 6 is a human monocytic cell line with several features of mature blood monocytes such as CD 14 antigen expression, phagocytotic ability, and the functional ability to produce cytokines. This line is often used as an in vitro model to demonstrate the actions of monocytes. In our study, the production of cytoki...

journal_title：Immunobiology

authors： Neustock P,Brand JM,Kruse A,Kirchner H

更新日期：1993-07-01 00:00:00

abstract：:C1q binds to many non-self and altered-self-materials. These include microorganisms, immune complexes, apoptotic and necrotic cells and their breakdown products, and amyloids. C1q binding to amyloid fibrils found as extracellular deposits in tissues, and subsequent complement activation are involved in the pathology o...

journal_title：Immunobiology

authors： Sim RB,Kishore U,Villiers CL,Marche PN,Mitchell DA

更新日期：2007-01-01 00:00:00

abstract：:Germinal centers are the anatomic sites for the generation of high affinity immunoglobulin expressing plasma cells and memory B cells. The germinal center B cells that are precursors of these cells circulate between the light zone B cell population that interact with antigen laden follicular dendritic cells (FDC) and ...

journal_title：Immunobiology

authors： Donius LR,Weis JJ,Weis JH

更新日期：2014-06-01 00:00:00

abstract：:Reggie-1/flotillin-2 is a plasma membrane-associated cytoplasmic protein, which defines non-caveolar raft microdomains. Reggie-1/flotillin-2 is enriched in detergent insoluble (TX100) membrane fractions (DIG), co-localizes with activated GPI-linked proteins and the fyn-kinase in neurons and T cells, and thus apparentl...

journal_title：Immunobiology

authors： Solomon S,Masilamani M,Rajendran L,Bastmeyer M,Stuermer CA,Illges H

更新日期：2002-03-01 00:00:00

abstract：:Dendritic cells (DC) are efficient antigen presenting cells with the ability to activate naïve T cells. Murine DC represent a heterogeneous population that can be subdivided into distinct subsets, including the conventional DC (cDC) which are either CD4(-)CD8(-) (DN), CD4(+)CD8(-) (CD4+) or CD4(-)CD8(+) (CD8+) subsets...

journal_title：Immunobiology

authors： Proietto AI,O'Keeffe M,Gartlan K,Wright MD,Shortman K,Wu L,Lahoud MH

更新日期：2004-01-01 00:00:00

abstract：:A cyclophosphamide (CP)-induced tolerance system in mice that primarily consists of donor cell injection followed by CP-treatment was found useful for inducing a long-lasting allo- or xeno-tolerance to various solid organs. In the cells-followed-by-CP system, the sequential mechanisms of tolerance were clarified using...

journal_title：Immunobiology

authors： Mayumi H,Umesue M,Nomoto K

更新日期：1996-07-01 00:00:00

abstract：:Several papers have demonstrated the importance of substances from natural sources which can exert powerful anti-inflammatory effects. In this respect, hydroxytyrosol, one of the major elements of the phenolic components of olive oil, has been extensively studied for its anti-inflammatory activities and safety profile...

journal_title：Immunobiology

authors： Bonura A,Vlah S,Longo A,Bulati M,Melis MR,Cibella F,Colombo P

更新日期：2016-12-01 00:00:00

abstract：:Macrophages are major effector cells of the innate immune system, and appropriate regulation of macrophage function requires the integration of multiple signalling inputs derived from the recognition of host factors (e.g. interferon-gamma/IFNgamma) and pathogen products (e.g. toll-like receptor/TLR agonists). The prof...

journal_title：Immunobiology

authors： Schroder K,Sweet MJ,Hume DA

更新日期：2006-01-01 00:00:00

abstract：:Antibody-mediated elimination of foreign antigens contributes to immune protection from viral infection. We have generated phycoerythrin-conjugated HIV-1 Gag/p24 and influenza virus nucleoprotein tetramers for flow cytometric analysis of blood cell populations involved in antibody-mediated immunity. We show that in th...

journal_title：Immunobiology

authors： Reiche S,Bussmann BM,Dwai Y,Jassoy C

更新日期：2010-03-01 00:00:00

abstract：:The T effector lymphocytes of delayed type hypersensitivity reactions (TDH) are regulated by a complex T suppressor (Ts) cell circuit. Induction of TDH cells requires Ia+ adherent cells as antigen-presenting cells. Little is known about the antigen presentation of the induction of Ts cells. We describe an experimental...

journal_title：Immunobiology

authors： Knop J,Malorny U,Michels E,Sorg C

更新日期：1984-12-01 00:00:00

abstract：:L-alanine was shown earlier to play a significant role for the proliferation of lymphocytes in vitro. In the present work the effect of L-alanine and some other amino acids on thymocyte proliferation was studied in vivo by local administration into one thymus lobe of guinea pigs. Proliferating cells were pulse labelle...

journal_title：Immunobiology

authors： Hägglund B,Sandberg G

更新日期：1993-06-01 00:00:00