Suprasellar tumors in children: a review of clinical manifestations and managements.

abstract：:Adjuvant systemic treatments have greatly improved the prognosis of women with early breast cancer. Combination chemotherapy and, for patients with oestrogen receptor-positive (ER+) tumours, endocrine treatment has been found to reduce the frequency of relapse and improve survival. New adjuvant strategies include the ...

journal_title：Cancer

authors： Coleman RE

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is available in terms of primary chemothera...

journal_title：Cancer

authors： Cocconi G,Di Blasio B,Boni C,Bisagni G,Ceci G,Rondini E,Bella M,Leonardi F,Savoldi L,Camisa R,Bruzzi P

更新日期：2002-07-15 00:00:00

abstract：:Six breast cancer patients were treated recently for renal insufficiency secondary to neoplasic involvement of the ureters. This complication usually occurs in long standing hormonal-dependent breast cancer with bone metastases. Diagnosis was performed by abdominal echography. Ureteral catheterization or percutaneous ...

journal_title：Cancer

authors： Recloux P,Weiser M,Piccart M,Sculier JP

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38 conjugate, had encouraging efficacy in the phase 1 clinical trial. This report further examines the pharmacokinetics and safety of multiple cycles of IMMU-132 at doses of 8 or 10 mg/kg in patien...

journal_title：Cancer

authors： Ocean AJ,Starodub AN,Bardia A,Vahdat LT,Isakoff SJ,Guarino M,Messersmith WA,Picozzi VJ,Mayer IA,Wegener WA,Maliakal P,Govindan SV,Sharkey RM,Goldenberg DM

更新日期：2017-10-01 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：:Cytopathologists recognize that certain Pap smear findings are suspicious for endometrial pathology in menopausal women. To study their prognostic importance in the directed cervical smear, six parameters were used to evaluate smears for evidence of an endometrial lesion: the presence of (1) histiocytes, (2) multinucl...

journal_title：Cancer

authors： Zucker PK,Kasdon EJ,Feldstein ML

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are a group of effector cells that act nonspecifically against tumor cells. The correlation between intratumoral NK cell infiltration and clinicopathologic features remains unclear. METHODS:The authors selected 146 patients with gastric carcinoma who underwent gastrectomy at Kagosh...

journal_title：Cancer

authors： Ishigami S,Natsugoe S,Tokuda K,Nakajo A,Che X,Iwashige H,Aridome K,Hokita S,Aikou T

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Intracranial primitive neuroectodermal tumors (PNETs) occur in the supratentorial and infratentorial regions of the brain. Although histologically similar, the natural history of the tumor at each site differs. The study goal was to determine whether there was evidence of a genetic difference between suprate...

journal_title：Cancer

authors： Russo C,Pellarin M,Tingby O,Bollen AW,Lamborn KR,Mohapatra G,Collins VP,Feuerstein BG

更新日期：1999-07-15 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for tumor growth, progression, and metastases. Microvessel density (MVD), a measure of tumor angiogenesis, has been found to have prognostic significance in many tumor types for predicting metastasis and survival. METHODS:Between 1979-1989, 56 cases of FIGO Clinical Stage I and II ...

journal_title：Cancer

authors： Kaku T,Hirakawa T,Kamura T,Amada S,Kinukawa N,Kobayashi H,Sakai K,Ariyoshi K,Sonoda K,Nakano H

更新日期：1998-10-01 00:00:00

abstract：:High calcitonin levels noted on a totally healthy 49-year-old man participating in a calcitonin control project led to a presumptive diagnosis of medullary carcinoma. Complete thyroid studies augmented by selective catheterization and quantitative calcitonin studies confirmed the clinical impression of medullary carci...

journal_title：Cancer

authors： White IL,Vimadalal SD,Catz B,Van de Velde R,LaGanga T

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:Screening for and the aggressive treatment of prostate carcinoma are controversial, but they are nevertheless being practiced in the U.S. Current clinical studies of the effectiveness of screening will take years to complete. Meanwhile, screening for prostate carcinoma is already having an effect on society....

journal_title：Cancer

authors： Brawley OW

更新日期：1997-11-01 00:00:00

abstract：:From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...

journal_title：Cancer

authors： Takita H,Regal AM,Antkowiak JG,Rao UN,Botsoglou NK,Lane WW

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Gastrin-releasing peptide (GRP) is an autocrine growth factor in patients with small cell lung carcinoma (SCLC). The authors developed a reverse transcriptase-polymerase chain reaction (RT-PCR) assay for the detection of SCLC cells in the peripheral blood and the pleural effusion using preproGRP mRNA as a ta...

journal_title：Cancer

authors： Saito T,Kobayashi M,Harada R,Uemura Y,Taguchi H

更新日期：2003-05-15 00:00:00

abstract：BACKGROUND:Ovarian tumors of borderline malignancy have a less aggressive behavior and tend to occur at a younger age than their invasive counterparts. The role and extent of fertility-sparing conservative treatments is under continuous evaluation. METHODS:The current study was a retrospective review of 82 patients wi...

journal_title：Cancer

authors： Gotlieb WH,Flikker S,Davidson B,Korach Y,Kopolovic J,Ben-Baruch G

更新日期：1998-01-01 00:00:00

abstract：:The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

journal_title：Cancer

authors： Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Interferon is approved for adjuvant treatment of patients with stage IIB/III melanoma. The identification of predictive markers that would permit selection of patients would be beneficial. Specific human leukocyte antigen (HLA) class I and II antigens have previously shown an association with response to the...

journal_title：Cancer

authors： Gogas H,Kirkwood JM,Falk CS,Dafni U,Sondak VK,Tsoutsos D,Stratigos A,Markopoulos C,Pectasides D,Spyropoulou-Vlachou M

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:Nonsmall cell lung carcinomas (NSCLCs) are associated with very dismal prognoses, and adjuvant chemotherapy, including irinotecan, taxanes, platin, and vinca alkaloid derivatives, offer patients only slight clinical benefits. Part of the chemoresistance of NSCLC results from the expression in NSCLC cells of ...

journal_title：Cancer

authors： Mathieu A,Remmelink M,D'Haene N,Penant S,Gaussin JF,Van Ginckel R,Darro F,Kiss R,Salmon I

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:The influence of HER-2/neu on prognosis of breast cancer is controversial. The authors investigated by immunohistochemistry in node-positive disease the influence of the pattern of immunostaining (membranous or cytoplasmic) on outcome and the prognostic significance of this marker in patients receiving or no...

journal_title：Cancer

authors： Têtu B,Brisson J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The altered and anomalous expression of carbohydrate antigens (CA) occur in patients with lung carcinomas. METHODS:To investigate the relationship between prognosis and immunohistochemical findings of CA in serum and pulmonary adenocarcinomas (PA), PA specimens surgically resected from 102 patients were stu...

journal_title：Cancer

authors： Kawai T,Suzuki M,Kase K,Ozeki Y

更新日期：1993-09-01 00:00:00

abstract：:Patients with small cell bronchogenic carcinoma, in a study utilizing laminar-air-flow-protected environments, oral prophylactic broad spectrum non-absorbable antibiotics (PNAA), and intensive combination chemotherapy, were examined to determine the effects of PNAA on serum biochemical values and on gastrointestinal a...

journal_title：Cancer

authors： Cohen MH,Creaven PJ,Fossieck BE,Johnston AV,Williams CL

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) tests are commonly used to assess human epidermal growth factor 2 (HER2) status of tumors in patients with breast cancer. This analysis evaluates the likely cost-effectiveness of expanded retesting to assess HER2 tumor status in women w...

journal_title：Cancer

authors： Garrison LP Jr,Lalla D,Brammer M,Babigumira JB,Wang B,Perez EA

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Chemotherapy-induced nausea and vomiting remain common, distressing side effects of chemotherapy. It has been reported that acupressure prevents chemotherapy-induced nausea in adults, but it has not been well studied in children. METHODS:In this multicenter, prospective, randomized, single-blind, sham-contr...

journal_title：Cancer

authors： Dupuis LL,Kelly KM,Krischer JP,Langevin AM,Tamura RN,Xu P,Chen L,Kolb EA,Ullrich NJ,Sahler OJZ,Hendershot E,Stratton A,Sung L,McLean TW

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:The authors assessed the prognostic significance of abnormal cyclin dependent kinase inhibitor (CDKI) expression in adenocarcinomas of the uterine cervix. METHODS:Population-based, archival material from patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I and II cervical adeno...

journal_title：Cancer

authors： Alfsen GC,Reed W,Sandstad B,Kristensen GB,Abeler VM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations. METHODS:We recently performed a screening study for bladder cancer using a urine-based tumor marker in 1502 subjects at high risk based on aged > or = 50 years, > or = 10-year smoking history, a...

journal_title：Cancer

authors： Elias K,Svatek RS,Gupta S,Ho R,Lotan Y

更新日期：2010-06-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to correlate pretreatment computed tomography and magnetic resonance imaging studies with outcomes for patients with squamous or basal cell carcinoma of the skin and clinical perineural invasion. METHODS:Between 1986 and 2002, 45 patients were treated with radiotherapy...

journal_title：Cancer

authors： Galloway TJ,Morris CG,Mancuso AA,Amdur RJ,Mendenhall WM

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:African-American (AA) and white patients with early-stage disease who were treated with breast conservation therapy (BCT) were examined to detect differences in clinicopathologic features and outcomes as a function of race. METHODS:Clinical data from the charts of 2164 white and 207 AA patients treated with...

journal_title：Cancer

authors： Moran MS,Yang Q,Harris LN,Jones B,Tuck DP,Haffty BG

更新日期：2008-11-01 00:00:00

abstract：:Antibodies to herpes simplex viral-induced antigens (HSVIA) were assayed by an indirect immunofluorescent technique in 93 regular cigarette smokers, 75 of whom also imbibed alcoholic beverages. Controls were 94 nonsmoking, nondrinking volunteers matched with the smoker for age and sex. IgA antibodies to HSVIA were det...

journal_title：Cancer

authors： Smith HG,Horowitz N,Silverman NA,Henson DE,Chretien PB

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:It is questionable whether enrollment on clinical trials offers any survival advantage at the population level over standard-of-care treatment. The objectives of this study were to describe the impact of trial enrollment on event-free survival and overall survival in pediatric acute myeloid leukemia (AML) us...

journal_title：Cancer

authors： Truong TH,Pole JD,Barber R,Dix D,Kulkarni KP,Martineau E,Randall A,Stammers D,Strahlendorf C,Strother D,Sung L

更新日期：2018-10-15 00:00:00

abstract：:Disagreement persists about the superiority of Reagan and Ng's method over that of Broders' for the histologic grading of squamous carcinoma of the cervix. Uncertainty about the predictive value and reproducibility of any of the grading methods prompted a comparison of factors previously suggested as indicating the bi...

journal_title：Cancer

authors： Zaino RJ,Ward S,Delgado G,Bundy B,Gore H,Fetter G,Ganjei P,Frauenhoffer E

更新日期：1992-04-01 00:00:00