Abstract:
:The effect of a prolonged course of oral acyclovir was evaluated in 55 pts with recurrent genital herpes (36 men and 19 women). The pts were voluntarily enrolled after an acute episode, with tissue culture viral isolation. All the pts received an initial course with 200 mg of acyclovir x 5 for 10 days. Then they were randomly assigned to two groups (double-blind), one received 400 mg t.d. for 6 months and the other placebo. Clinical, virological and immunological follow-up included: tissue culture viral isolation, HSV antibody detection, serum Igs levels, T and B cell count, T-cell subsets (OKT3, OKT4, OKT8), C3 and phagocytosis test. The drug was well tolerated with hardly any side effects. Recurrences diminished dramatically in acyclovir treated pts, in contrast with those receiving placebo who did not show modification in viral recurrences. The immunological study was normal in most pts and did not change significantly during the trial.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Velasco M,Saavedra T,Sepúlveda C,Suárez Msubject
Has Abstractpub_date
1991-08-01 00:00:00pages
876-80issue
8eissn
0034-9887issn
0717-6163journal_volume
119pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Basedow Graves disease (BGD) is the leading cause of hyperthyroidism. The characteristics of patients seen at a university hospital may differ from those described in the general population. AIM:To describe the clinical features of patients with BGD seen at a university hospital. MATERIAL AND METHODS:Revie...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000400003
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Microtia is a congenital defect characterized by disturbances in the size and form of the ear lobe. Anotia corresponds to the absence of the ear lobe. AIM:To study the prevalence of microtia and anotia at the Maternity of the University of Chile Clinical Hospital. MATERIAL AND METHODS:Analysis of the datab...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006001000012
更新日期:2006-10-01 00:00:00
abstract::The "Revista Medica de Chile" founded in 1872 is the second oldest medical journal in Latin America after the "Gaceta Medica de Mexico" (1864). Among medical journals in the world it is placed 24. It has been published monthly without interruption, except for the period January through December 1891, due to the revolu...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Few trials have studied the prevalence of sexual dysfunction (SD) and related risk factors in postmenopausal women using the DSM-IV criteria. AIM:To evaluate the prevalence of SD in menopausal women and the impact of risk factors. PATIENTS AND METHODS:Five hundred thirty four healthy women, 40 to 64 years ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::We report a 25 years old woman with a four years history of end stage renal disease on hemodialysis. During the last two years of follow up, multiple tender nodules appeared in the left clavicle and ribs. These were diagnosed as brown tumors, secondary to osteitis fibrosa cystica, in the context of a secondary hyperpa...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Glycine inhibits the formation of advanced glycation end products that may cause central and peripheral neuronal damage, affecting also the auditory nerve. AIM:To evaluate the effect of glycine on auditory nerve conduction and hearing level among patients with type 2 diabetes mellitus and auditory neuropath...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010001100006
更新日期:2010-10-01 00:00:00
abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract::Sepsis from an infected cardiac valve can lead to bacterial seeding and destruction of the arterial wall with formation of a mycotic aneurysm. The natural history of these lesions is the rupture. We report the case of a 20 year old female who was admitted to our institution with massive mitral regurgitation and emboli...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:The age at which children born preterm normalize their bone mineral density, is not well known. AIM:To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. PATIENTS AND METHODS:Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weigh...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:The classic diagnosis of Barret esophagus is based on the finding of three of more cm of distal esophagus covered by specialized columnar epithelium. However, at the present time, it is based on the presence of intestinal metaplasia in the junction of squamous-columnar mucosae. AIM:To assess the prevalence ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract::This is a translation into Spanish, done by Mario Uribe, M.D., F.A.C.S., and authorized by the Conference Organization, of the official statements signed by The Transplantation Society, The International Society of Nephrology and the representatives who participated at a WHO sponsored Conference held in Istambul, Turk...
journal_title:Revista medica de Chile
pub_type: 共识发展会议,杂志文章
doi:10.4067/S0034-98872009000800019
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Streptococcus agalactiae or group B streptococcus, GBS, is the leading cause of neonatal and maternal infections and an opportunistic pathogen in adults with underlying disease. In the last decade, a dramatic increase in the resistance of this microorganism to erythromycin and clindamycin has been observed. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000500003
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:The economic impact of irritable bowel syndrome (IBS) in Mexico in terms of excessive diagnostic testing can be considerably reduced if the recommendations of the Latin American Consensus (LATAM) for IBS are followed. AIM:To estimate the economic impact of IBS in terms of excessive diagnostic testing. MATE...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872008001100005
更新日期:2008-11-01 00:00:00
abstract::We analyze the effect of inspiratory muscle training (IMT) in patients with chronic obstructive pulmonary disease (COPD), with special emphasis on its effects on inspiratory muscle function and clinical outcomes. We reviewed only randomized, controlled studies that have either controlled both the load and the breathin...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Behçet's disease (BD) is a rare multisystemic inflammatory disease that is potentially disabling and may cause death. AIM:To describe the characteristics of BD patients from two Chilean centers. PATIENTS AND METHOD:Retrospective review of the clinical records of patients with BD attended in two rheumatolog...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009001000008
更新日期:2009-10-01 00:00:00
abstract::Considering that a high proportion of the Chilean general population smokes, the Chilean Society of Respiratory Diseases in collaboration with the Chilean Societies of Cardiology and, Endocrinology and Diabetes, formed an interdisciplinary group, who issued a set of recommendations for the treatment of the smoker, met...
journal_title:Revista medica de Chile
pub_type: 杂志文章,实务指引
doi:10.4067/s0034-98872017001101471
更新日期:2017-11-01 00:00:00
abstract::Jehovah Witnesses cite religious motives to refuse transfusions of whole blood or its components for themselves and their children, even when life is endangered. An ethical analysis of decision making in health problems is made, giving priority to the alternatives chosen by the patient. One of the elements that turns ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Hematopoietic precursors transplantation is a therapeutic alternative for leukemia, some metabolic diseases and some immune deficiency syndromes. In its allogeneic variety leukemia eradication is based in the conditioning prior to transplantation and the allograñ effect against leukemia. Umbilical cord blood is an alt...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000800009
更新日期:2009-08-01 00:00:00
abstract::We report a woman with insulin resistance associated with hyperandrogenism and acanthosis nigricans (HAIR-AN syndrome) treated during 30 days with the prolonged action opioid antagonist Naltrexone. During its administration, decreases in basal blood glucose and serum insulin, insulin and glucose response to a glucose ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::The preliminary results of a prospective and cooperative protocol for the treatment of soft tissue sarcomas of trunk and extremities, stages IB-IIIB are presented. Thirty one patients (17 males, 22 with a tumor larger than 5 cm) aged 16 to 68 years, were treated with one dose of epirubicin 70 mg/m2 i.v. and radiothera...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::The aim of this work is to analyze the usefulness of rheumatoid factor determination in synovial fluid. One hundred twenty nine patients (29 with rheumatoid arthritis), in whom rheumatoid factor was simultaneously determined in serum and synovial fluid, were retrospectively analyzed. Serum rheumatoid factor had a 48% ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Pulmonary hypertension is a clinical condition with a low prevalence, but carries high morbidity and mortality. Important advances in the understanding of this disease and in its therapy have occurred. A particular scenario is pulmonary hypertension in patients undergoing non-cardiac as well as cardiac surgery. The ai...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872010000400016
更新日期:2010-04-01 00:00:00
abstract::Medicine is progressively loosing its prestige and efficacy and needs to rebuild the moral values that maintain the tacit social contract subscribed between doctors and patients. This altruistic commitment to serve people has been devaluated by changes in health systems, by advances in knowledge and by social and econ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000500016
更新日期:2006-05-01 00:00:00
abstract::Two patients with traumatic pancreatic pseudocyst are presented. One patient was treated with percutaneous drainage and the other was operated on to perform a cystoenterostomy. Both patients recovered successfully. Diagnosis and treatment of this condition is discussed. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract::A lateral abdominal bruit is considered an important finding for the detection of renovascular hypertension. However, the precision and accuracy of new techniques such as angiography, Doppler ultrasound and studies with radioisotopes have changed its value and clinical interpretation. We report a 75 years old woman wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::In the last decades, there has been an increase in life expectancy in the world, with the consequent modification in the proportion of adults over 60 years. This is accompanied by an increase in pathologies for which aging is the main risk factor, such as dementia and hearing loss, which profoundly affect the quality ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872020000801128
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:In a rapidly changing culture like ours, with emphasis on productivity, there is a strong need to find the meaning of health care work using learning instances that privilege reflection and face to face contact with others. The Diploma in Health and Humanization (DSH), was developed as an interdisciplinary s...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000300008
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Felodipine is a calcium channel inhibitor with high vascular selectivity. AIM:To study the effectiveness of felodipine in the treatment of essential hypertension in subjects older than 64 years old. PATIENTS AND OUTCOME:Fifty subjects were studied. After a washout period of four weeks, subjects received a ...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Restless legs syndrome (RLS) affects 10% of the general population. AIM:To analyze a series of patients with a minimum follow-up period of four years, treated during an interval of 14 years. MATERIAL AND METHODS:Retrospective analysis of medical records of 200 patients assessed and followed by the authors ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016001200007
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Framingham risk score (FRS) has limitations and can underestimate risk. Carotid ultrasound to measure intima media thickness or plaques is recommended for cardiovascular risk assessment. AIM:To determine the prevalence of subclinical atherosclerosis in asymptomatic subjects classified as low and intermediat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000100005
更新日期:2016-01-01 00:00:00