[Umbilical cord hematopoietic precursors transplantation. Report of five patients].

Abstract:

:Hematopoietic precursors transplantation is a therapeutic alternative for leukemia, some metabolic diseases and some immune deficiency syndromes. In its allogeneic variety leukemia eradication is based in the conditioning prior to transplantation and the allograñ effect against leukemia. Umbilical cord blood is an alternative source of hematopoietic precursors when there are no HLA compatible relatives available. Between 2003 and 2007 we have performed five umbilical cord blood transplant in adult patients in a University hospital. All patients had malignant diseases. Conditioning protocols were ablative in all except in one patient and in all, more than one unit of umbilical cord blood was used. Hematopoietic engraftment was confirmed in all patients and the main complications registered were infectious and associated to immunosuppression.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Burotto P M,Bertín C-M P,Galindo A H,Garrido S M,Melgoza P G,Nervi N B,Ramírez V P,Ocqueteau T M,Besa de C P,García V V,Jara A V,Alvarez J E,Betancur B M,Rivera L M,Alvarez Z M

doi

/S0034-98872009000800009

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

1054-60

issue

8

eissn

0034-9887

issn

0717-6163

pii

S0034-98872009000800009

journal_volume

137

pub_type

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