[Bone mineral density in school age children born preterm ].

Abstract:

BACKGROUND:The age at which children born preterm normalize their bone mineral density, is not well known. AIM:To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. PATIENTS AND METHODS:Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weight, present weight and height, bone age, calcium and phosphate intake at the first year of life and at the current age were assessed. Bone mineral density was measured by single photon X ray absorptiometry in the dominant forearm. A blood sample was obtained to measure insulin growth factor 1 (IGF-1). As a control group, 105 healthy age-paired infants born at term, were studied. RESULTS:Bone mineral density was significantly lower in infants born preterm than in their term counterparts (0.273 +/- 0.01 g/cm2 and 0.302 +/- 0.01 g/cm2 respectively, p < 0.001). There was a positive correlation between bone mineral density and IGF-1 (r = 0.49, p = 0.01). No correlation with the other measured parameters was observed. CONCLUSIONS:Infants that were born preterm have a lower bone mineral density at 5 to 7 years of age than their term controls. Bone mineral density correlates with IGF-1.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Milinarsky A,Fischer S,Giadrosich V,Hernández MI,Torres MT

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

1289-94

issue

11

eissn

0034-9887

issn

0717-6163

journal_volume

131

pub_type

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